The development of the normal Schirmer tear test results during the dog's first year of life     

Manuella Oliveira Borges de Sampaio  Bret A. Moore  Nathália Mendonça de Seabra  Mariza Bortolini  Thayane Cristina Vieira  Camilla Bolmann Martins  Ana Leticia Groszewicz de Souza  Camila Marinelli Martins  Fabiano Montiani-Ferreira 《Veterinary ophthalmology》2023,26(3):184-190

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An investigation into an outbreak of pancytopenia in cats in the United Kingdom     

Barbara Glanemann  Karen Humm  Camilla Pegram  Daniel L. Chan 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(1):117-125

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The Effect of Levothyroxine Treatment on Resting Energy Expenditure of Hypothyroid Dogs     

Deborah S. Greco  Rod A.W. Rosychuk  Gregory K. Ogilvie  Lynn M. Harpold  Camilla H. Van  Liew 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1998,12(1):7-10

Thirty adult, client-owned dogs were diagnosed with hypothyroidism based on history, physical examination findings, hematologic and biochemical abnormalities, thyrotropin (TSH) response testing, endogenous canine thyrotropin (cTSH) concentration, or both, and total serum thryoxine concentration. All dogs received levothyroxine (L-thyroxine) at an initial dose of 22 μg/kg PO sid in either a tablet (13 dogs) or chewable form (17 dogs). Energy expenditure of each dog during apparent rest was estimated with an open-flow indirect calorimetry system by determining the rates of carbon dioxide production and oxygen consumption. Energy expenditure of apparent rest (EE) was lower in untreated hypothyroid dogs compared with reference values for EE. After treatment with L-thyroxine, EE of the hypothyroid dogs was significantly ( P < .05) higher than pretreatment values.  相似文献   

Fungal decomposition of sapwood and heartwood of European aspen,Populus tremula L.     

Camilla Wikstrm 《Forest Pathology》1975,5(6):349-356

In contrast to the woodrotting fungi which can only attack Populus tremula after felling, Phellinus tremulae successfully invades the central part of the living tree. Possible causes for this difference were investigated. It was found that sterile wood samples were decomposed more rapidly by saprophytic fungi than by parasitic fungi. With both types of fungi, heartwood was more resistant to decay than sapwood. It is postulated that living sapwood inhibits infection by most woodrotting fungi, but that P. tremulae can successfully overcome this barrier. This postulate cannot be confirmed by experiments using sterilized wood samples.  相似文献   

Allocation of mass in trees subject to nitrogen and magnesium limitation     

Wikström F  Ericsson T 《Tree physiology》1995,15(5):339-344

It has previously been shown that lack of magnesium, potassium or manganese depresses allocation of new mass to roots in trees, and that these elements often occur in low amounts in declining forest stands. A model for tree growth and nutrient uptake was used to examine the effect of allocation pattern of new plant mass on growth and development in soils with low nutrient concentrations. Growth parameters and empirical allocation functions from steady-state experiments with birch (Betula pendula Roth.) and Norway spruce (Picea abies (L.) Karst.) limited by N or Mg were used in the simulations. The simulation results show that plant nutrient concentration is sensitive to decreases in soil Mg concentration and is not counteracted by an increased allocation of plant mass to roots. A 50% reduction in the optimal soil Mg concentration decreased the plant Mg concentration to the threshold of survival, whereas a 50% reduction of soil N had much less effect. Birch was more sensitive to low soil Mg concentration than Norway spruce. We conclude that, in the discussion of forest decline, it may be important to consider the decreased allocation of mass to roots when Mg (or K or Mn) is in short supply.  相似文献   

Isolation and determination of alpha-dicarbonyl compounds by RP-HPLC-DAD in green and roasted coffee     

Daglia M  Papetti A  Aceti C  Sordelli B  Spini V  Gazzani G 《Journal of agricultural and food chemistry》2007,55(22):8877-8882

Glyoxal, methylglyoxal, and diacetyl formed as Maillard reaction products in heat-treated food were determined in coffee extracts (coffee brews) obtained from green beans and beans with different degrees of roast. The compounds have been reported to be mutagenic in vitro and genotoxic in experimental animals in a number of papers. More recently, alpha-dicarbonyl compounds have been implicated in the glycation process. Our data show that small amounts of glyoxal and methylglyoxal occur naturally in green coffee beans. Their concentrations increase in the early phases of the roasting process and then decline. Conversely, diacetyl is not found in green beans and forms later in the roasting process. Therefore, light and medium roasted coffees had the highest glyoxal and methylglyoxal content, whereas dark roasted coffee contained smaller amounts of glyoxal, methylglyoxal, and diacetyl. For the determination of coffee alpha-dicarbonyl compounds, a reversed-phase high performance liquid chromatography with a diode array detector (RP-HPLC-DAD) method was devised that involved the elimination of interfering compounds, such as chlorogenic acids, by solid phase extraction (SPE) and their derivatization with 1,2-diaminobenzene to give quinoxaline derivatives. Checks of SPE and derivatization conditions to verify recovery and yield, respectively, resulted in rates of 100%. The results of the validation procedure showed that the proposed method is selective, precise, accurate, and sensitive.  相似文献   

Characterization of commercial kava-kava herbal drug and herbal drug preparations by means of nuclear magnetic resonance spectroscopy   总被引：1，自引：0，他引：1  

Bilia AR  Bergonzi MC  Lazari D  Vincieri FF 《Journal of agricultural and food chemistry》2002,50(18):5016-5025

The efficiency of one- and two-dimensional NMR experiments in characterizing the content of the constituents of both herbal drugs and herbal drug preparations is demonstrated for kava-kava. These experiments directly detect active constituents represented by kavalactones in both a finely powdered herbal drug and a commercial extract. In addition, NMR spectroscopy can detect all other compounds present in the extract. As previously evidenced, NMR experiments can represent a generally applicable technique for rapid screening and are a complement to the classical analytical techniques such as high-performance thin-layer chromatography, high-performance liquid chromatography, capillary gas chromatography, and electrophoresis. These experiments can be considered a very simple and fast analytical method to obtain a fingerprint of the herbal drugs and their preparations, and to quantify the content of the active principles of the extract.  相似文献   

Use of a substrate/alliinase combination to generate antifungal activity in situ   总被引：5，自引：0，他引：5  

Fry FH  Okarter N  Baynton-Smith C  Kershaw MJ  Talbot NJ  Jacob C 《Journal of agricultural and food chemistry》2005,53(3):574-580

Allicin, an active ingredient of garlic, possesses a range of antimicrobial properties. Unfortunately, certain properties of the compound, such as chemical instability and low miscibility with water, have hampered its practical use in the past. Here, we show that it is possible to use a binary system consisting of the plant enzyme alliinase and its substrate alliin to generate allicin, and hence antifungal activity, in situ. During application, the two inactive components generate compounds that inhibit growth and infection-related development of the rice blast fungus Magnaporthe grisea. It is therefore possible to "trigger" biological activity in a controlled, yet effective manner. Apart from circumventing many of the drawbacks of allicin, this binary system has additional important advantages, such as low toxicity of its individual components and selective activation. Importantly, alliinase is also able to use different substrates, therefore paving the way to a range of novel, binary antimicrobial systems with custom-made chemical and biochemical properties.  相似文献   

Prevention of translational frameshifting by the modified nucleoside 1-methylguanosine   总被引：15，自引：0，他引：15  

G R Bj?rk  P M Wikstr?m  A S Bystr?m 《Science (New York, N.Y.)》1989,244(4907):986-989

The methylated nucleoside 1-methylguanosine (m1G) is present next to the 3' end of the anticodon (position 37) in all transfer RNAs (tRNAs) that read codons starting with C except in those tRNAs that read CAN codons. All of the three proline tRNA species, which read CCN codons in Salmonella typhimurium, have been sequenced and shown to contain m1G in position 37. A mutant of S. typhimurium that lacks m1G in its tRNA when grown at temperatures above 37 degrees C, has now been isolated. The mutation (trmD3) responsible for this methylation deficiency is in the structural gene (trmD) for the tRNA(m1G37)methyltransferase. Therefore, the three proline tRNAs in the trmD3 mutant have an unmodified guanosine at position 37. Furthermore, the trmD3 mutation also causes at least one of the tRNAPro species to frequently shift frame when C's are present successively in the message. Thus, m1G appears to prevent frameshifting. The data from eubacteria apply to both eukaryotes and archaebacteria.  相似文献   

木业企业如何为抑制气候变化做贡献     

Camilla Hair  管宁 《国际木业》2011,(6):24

英国第一个气候周(Climate Week)组织者称,采取主动应对气候变化的行动(pro-climate action)会有助于企业和生意的发展。各行各业都在积极采取行动支持抑制气候变化的努力。气候周是一个新的机会来展示最得意的成绩。方式多样,可以是开会,发表新的研究成果或只是宣传更有利于环境的实用的经营之道。气候周也是企业在对未来有重要意义的问题上取得领先地位的良机。木业企业如何为抑制气候变化做贡  相似文献