The relationships of birth weight, preweaning gain and postweaning gain with the bovine major histocompatibility system     

M J Stear  T S Pokorny  N E Muggli  R T Stone 《Journal of animal science》1989,67(3):641-649

A total of 739 cattle from nine breeds maintained at the Roman L. Hruska U.S. Meat Animal Research Center, Clay Center, Nebraska were tested for 42 class I antigens of the bovine major histocompatibility system (BoLA). Each antigen appears to be the product of a distinct co-dominant allele of the BoLA-A locus. The number of antigens present in each breed ranged from a minimum of 10 in Hereford to a maximum of 21 in Charolais cattle. There were large differences among breeds in the frequencies of antigens. The effect of each antigen on birth weight, preweaning weight gain and postweaning weight gain was estimated in a gene substitution model. Each breed was analyzed separately. There were significant effects of some BoLA antigens on birth weight, preweaning weight gain and postweaning weight gain, which is consistent with previous reports showing associations between the major histocompatibility system and growth parameters in mice, rats and pigs. However, further research is necessary to confirm these findings and to determine the biological mechanisms underlying these associations.  相似文献   

Lupus-Type "Anticoagulant" in a Dog With Hemolysis and Thrombosis   总被引：1，自引：1，他引：0  

Michael S. Stone  Ian B. Johnstone  Marjory Brooks  Trent K. Bollinger  Susan M. Cotter 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(1):57-61

A circulating anticoagulant was detected in a 2-year-old Chesapeake Bay Retriever with hemolytic anemia, nephrotic syndrome, thrombocytopenia, polyarthropathy, and pulmonary thromboembolism. A persistent prolongation of the activated partial thromboplastin time (aPTT) was detected, and it did not correct with repeated administration of fresh frozen plasma. The aPTT was still prolonged, with a 1:1 mixture of patient's plasma and normal dog plasma in vitro, suggesting the presence of a circulating inhibitor. Results of assays to characterize the inhibitor were compatible with those described for the lupus anticoagulant in human patients with systemic lupus erythematosus. Paradoxically, patients having the lupus anticoagulant are at increased risk for thrombosis. Pulmonary thromboembolism has been described as a frequent complication of immune-mediated hemolytic anemia in the dog, and the presence of a circulating anticoagulant should be considered as a potential mechanism.  相似文献   

Struggles toward rationality: the history of statistics and the rise of statistical thinking,1820-1900     

Stone M 《Science (New York, N.Y.)》1987,235(4793):1262-1263

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Releases in israel ofAphelinus perpallidus,a recently introduced parasite of the pecan blackmargined aphid,Monellia caryella     

F Man Sour  M. K. Harris  J. D. Stone  R. Bueno 《Phytoparasitica》1988,16(2):171-174

Six shipments totaling 3452 mummies of the blackmargined aphid,Monellia caryella (Fitch), parasitized withAphelinus perpallidus Gahan, were obtained by air freight during the years 1982-1985 from Texas A&M Research Center, El Paso, Texas. About two-thirds of the mummies did not yield parasites. A colony ofA. perpallidus was established in the laboratory. Under laboratory conditions the percentage of emerged parasites was higher than that in the imported mummies, and the parasite had very limited impact on the aphid population. Field releases of the parasite were made but no establishment ofA. perpallidus was observed through the years.  相似文献   

Effects of transportation on the tonic immobility fear reactions of broilers     

P. J. Cashman  Christine J. Nicol  R. B. Jones 《British poultry science》1989,30(2):211-221

1. The fear levels of broilers arriving from slaughter at 4 commercial processing plants were assessed using tonic immobility (TI) tests. The relative effects of selected variables were also examined.

2. Neither the position of the birds on the lorry, nor their sex, nor the ambient temperature nor the identity of the experimeter exerted any significant effects on tonic immobility reactions.

3. Although the longest and shortest immobility responses followed transportation in the fixed crates and metal modules respectively, system comparisons may be confounded by variations in the birds’ genetic and/or experiential backgrounds.

4. Both journey duration and waiting time before transport bore an unambiguous and positive linear relationship with mean TI duration. The duration of transit was the major factor determining fear levels following both commercial and simulated journeys.  相似文献   

Marked neutropenia in five tumor-bearing cats one week following single-agent vincristine sulfate chemotherapy     

Hahn KA KA  Fletcher CM  Legendre AM 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1996,25(4):121-123

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Rustic site draws a crowd to monitor global warming     

Stone R 《Science (New York, N.Y.)》1994,266(5184):360-361

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Program gives some States a head start in bid for grants     

Stone R 《Science (New York, N.Y.)》1994,263(5151):1218-1219

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Stability of porcine colostral immunoglobulins IgA, IgA2, and IgM to proteolytic enzymes.     

S S Stone  M Phillips  L J Kemeny 《American journal of veterinary research》1979,40(5):607-612

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The greening of ;green science' means new jobs     

Stone R 《Science (New York, N.Y.)》1992,257(5077):1730-1731

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