Bovine spongiform encephalopathy in Northern Ireland: epidemiological observations 1988-1990.     

G O Denny  J W Wilesmith  R A Clements  W D Hueston 《The Veterinary record》1992,130(6):113-116

This study describes the epidemiological features of bovine spongiform encephalopathy (BSE) in Northern Ireland where the first case occurred in November 1988. They were very similar to those observed in Great Britain except that the annual incidence of BSE in 1990 in Northern Ireland, 2.3 confirmed cases per 10,000 adult cows, was approximately one 10th of that in Great Britain. The findings were also consistent with the current hypothesis that affected cattle had been exposed to a scrapie-like agent via cattle feedstuffs containing ruminant-derived protein. However, a preliminary investigation of the potential sources of infection for cattle in Northern Ireland did not provide any conclusive evidence.  相似文献   

Canine total hip replacement using a cementless threaded cup and stem: a review of 55 cases          下载免费PDF全文

H. R. Denny  T. W. Maddox  E. J. Comerford 《The Journal of small animal practice》2018,59(6):350-356

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Effect of nutrition during calfhood and peripubertal period on serum metabolic hormones, gonadotropins and testosterone concentrations, and on sexual development in bulls     

Brito LF  Barth AD  Rawlings NC  Wilde RE  Crews DH  Mir PS  Kastelic JP 《Domestic animal endocrinology》2007,33(1):1-18

The objective of the present study was to characterize the effects of nutrition on circulating concentrations of metabolic hormones, gonadotropins, and testosterone during sexual development in bulls. Nutrition regulated the hypothalamus-pituitary-testes axis through effects on the GnRH pulse generator in the hypothalamus and through direct effects on the testes. Pituitary function (gonadotropin secretion after GnRH challenge) was not affected by nutrition. However, nutrition affected LH pulse frequency and basal LH concentration during the early gonadotropin rise (10-26 weeks of age). There were close temporal associations between changes in insulin-like growth factor-I (IGF-I) concentrations and changes in LH pulse frequency, suggesting a role for IGF-I in regulating the early gonadotropin rise in bulls. The peripubertal increase in testosterone concentration was delayed in bulls with lesser serum IGF-I concentrations (low nutrition), suggesting a role for IGF-I in regulating Leydig cell function. Serum IGF-I concentrations accounted for 72 and 67% of the variation in scrotal circumference and paired-testes volume, respectively (at any given age), indicating that IGF-I may regulate testicular growth. Bulls with a more sustained elevated LH pulse frequency during the early gonadotropin rise (high nutrition) had greater testicular mass at 70 weeks of age relative to the control group (medium nutrition), despite no differences in metabolic hormone concentrations after 26 weeks of age. Therefore, gonadotropin-independent mechanism regulating testicular growth might be dependent on previous gonadotropin milieu.  相似文献   

The surgical treatment of fractures of the olecranon in the horse.     

H R Denny 《Equine veterinary journal》1976,8(1):20-25

Methods of treating fractures of the olecranon in the horse are reviewed. A further 4 cases are recorded in which the fracture was treated by open reduction and fixation with a heavy duty Venable's plate placed on the caudal aspect of the ulna. Three cases had an oblique fracture through the semilunar notch; this was complicated in one by a fracture of the lateral half of the radial head which resulted in subluxation of the radio-humeral joint. The fracture of the radial head was treated by open reduction and fixation with a lag screw. The fourth case had an oblique fracture of the olecranon just proximal to the semilunar notch, complicated by a fracture of the anconeal process which was removed. The fractures healed within 10 weeks and the plates were removed in all 4 cases. During follow-up periods ranging from 10 to 26 months, all 4 animals became sound.  相似文献   

Radial carpal bone fractures in 15 dogs     

Li A  Bennett D  Gibbs C  Carmichael S  Gibson N  Owen M  Butterworth SJ  Denny HR 《The Journal of small animal practice》2000,41(2):74-79

Between 1977 and 1992, 15 adult dogs were presented to the Universities of Bristol, Glasgow, Liverpool and London with fractures of the radial carpal bone which had occurred without a known episode of violent trauma. Eleven of the dogs were boxers and the other breeds affected were a Pharaoh hound, rottweiler, springer spaniel and a greyhound. The condition was bilateral in three cases. Eleven dogs were treated surgically by cast immobilisation (four cases), fragment removal (one case), lag screw fixation (three cases), pan-carpal arthrodesis (one case) and lag screw reduction followed by pan-carpal arthrodesis (two cases). The remaining four dogs were treated conservatively with rest and tactical use of non-steroidal anti-inflammatory drugs. Follow-up periods ranged from two months to 11 years. Varying degrees of lameness, which tended to be exacerbated by exercise, persisted in all cases. The radial carpal bone appears to have at least three separate centres of ossification which eventually fuse; their planes of fusion correspond approximately to the two main fracture lines. These areas of fusion could be weak points within the radial carpal bone.  相似文献   

Factors affecting urine reagent strip blood results in dogs and nonhuman primates and interpretation of urinalysis in preclinical toxicology studies: a Multi‐Institution Contract Research Organization and BioPharmaceutical Company Perspective          下载免费PDF全文

Adam D. Aulbach  Eric Schultze  Niraj K. Tripathi  Robert L. Hall  Michael R. Logan  Denny J. Meyer 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2015,44(2):229-233

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Influence of pH on the toxicity of aluminium and other inorganic contaminants to East Coast striped bass     

Denny R. Buckler  Paul M. Mehrle  Laverne Cleveland  F. James Dwyer 《Water, air, and soil pollution》1987,35(1-2):97-106

The toxicity of Al and a mixture of inorganic contaminants to young striped bass Morone saxatilis in soft fresh water was demonstrated to be age- and pH-dependent. Toxicity of the contaminants was increased with decreases of pH of the test waters. The interaction between low pH from acid deposition and inorganic contaminants should be considered as a possible factor contributing to the decline in abundance of east coast striped bass.  相似文献   

FITC: Something New or More of the Same?     

Denny BC 《Science (New York, N.Y.)》1979,203(4384):961

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The high-technology fix     

Denny BC 《Science (New York, N.Y.)》1982,217(4562):781

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SECTION G (BOTANICAL SCIENCES) AND RELATED ORGANIZATIONS     

Trelease SF  Eames AJ  Foster AS  Denny FE  Martin GW  Whitney WA  Horr WH 《Science (New York, N.Y.)》1930,71(1832):156-159

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