Plant Poisoning in Animals          下载免费PDF全文

Herman J. Boermans 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(2):189-190

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Successful treatment of a horse with chronic, severe flexural deformity of the distal interphalangeal joint: A case report     

Stacey Tarr DVM  Doug Butler PhD  CJF  FWCF  Robert K. Shideler DVM  ACT 《Journal of Equine Veterinary Science》1993,13(12):711-714

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Potential hazards     

Herman WA 《Science (New York, N.Y.)》1978,200(4342):643-645

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Investigation of Interspecies Interactions within Marine Micromonosporaceae Using an Improved Co-Culture Approach     

Navid Adnani  Emmanuel Vazquez-Rivera  Srikar N. Adibhatla  Gregory A. Ellis  Doug R. Braun  Tim S. Bugni 《Marine drugs》2015,13(10):6082-6098

With respect to bacterial natural products, a significant outcome of the genomic era was that the biosynthetic potential in many microorganisms surpassed the number of compounds isolated under standard laboratory growth conditions, particularly among certain members in the phylum Actinobacteria. Our group, as well as others, investigated interspecies interactions, via co-culture, as a technique to coax bacteria to produce novel natural products. While co-culture provides new opportunities, challenges exist and questions surrounding these methods remain unanswered. In marine bacteria, for example, how prevalent are interspecies interactions and how commonly do interactions result in novel natural products? In an attempt to begin to answer basic questions surrounding co-culture of marine microorganisms, we have tested both antibiotic activity-based and LC/MS-based methods to evaluate Micromonosporaceae secondary metabolite production in co-culture. Overall, our investigation of 65 Micromonosporaceae led to the identification of 12 Micromonosporaceae across three genera that produced unique metabolites in co-culture. Our results suggest that interspecies interactions were prevalent between marine Micromonosporaceae and marine mycolic acid-containing bacteria. Furthermore, our approach highlights a sensitive and rapid method for investigating interspecies interactions in search of novel antibiotics, secondary metabolites, and genes.  相似文献   

Unravelling the impacts of disturbance type and regeneration on movement of threatened species     

Finnegan  Laura  Viejou  Rebecca  MacNearney  Doug  Pigeon  Karine E.  Stenhouse  Gordon B. 《Landscape Ecology》2021,36(9):2619-2635

Landscape Ecology - Anthropogenic disturbance alters animal movements. Large mammals require vast areas to meet their needs, and they encounter anthropogenic disturbances frequently during daily...  相似文献   

The incredible fungal genus —Drechslera — and its phytotoxic ophiobolins     

Gary Strobel  Doug Kenfield  Fumio Sugawara 《Phytoparasitica》1988,16(2):145-152

ManyDrechslera species that haveCochliobolus sp. as a perfect stage produce a related group of ophiobolins, sesterterpenoids (C-25’s), which are phytotoxic to a wide range of plants. One of the most toxic ophiobolins is 6-epiophiobolin A and it is produced by all of theDrechslera species thus far studied. On the other hand, some novel ophiobolins have been found inD. oryzae: ophiobolin J, 6-epiophiobolin I, and 8-deoxyophiobolin J. Potentially, genetic crosses made between these fungi could yield novel organisms, producing novel combinations of the ophiobolins, and thus new pathotypes. Ophiobolins are being used in tissue culture systems to screen plants for sensitivity to these toxins. Paper presented at the Bat-Sheva Seminar on Host - Fungus Interaction, Jerusalem, Israel (March 14–25,1988).  相似文献   

Molecular modifications of benzylphenol and benzyl-1,3-benzodioxole types of insect chemosterilants     

Gyrgy Matolcsy  Ren Feyereisen  Herman Van Mellaert  gnes Pl  Lszl Varjas  Ivn Blai  Pter Kulcsr 《Pest management science》1986,17(1):13-24

Rationally planned structural modifications were carried out on benzylphenols and benzyl-1,3-benzodioxoles described as fly chemosterilants and as anti-juvenile hormones. The introduction of a prop-2-ynyloxy group at various sites of the molecule resulted in compounds with a moderate inhibitory action on cytochrome P-450 mono-oxygenases, as measured by aldrin epoxidation. One compound, 5-(4-methoxybenzyl)-6-prop-2-ynyloxy-1,3-benzodioxole, revealed chemosterilant activity on Phormia regina, but its activity was less than that of the parent compounds. 2,4-Di-tert-butyl-6-[4-(3-methoxy-3-methylbutoxy)benzyl]phenol, which possessed a juvenoid structure, revealed no juvenile hormone (JH) activity but showed a high sterilant effect against Dysdercus cingulatus. In contrast to the parent substances, none of the tested compounds showed a detectable anti-JH effect in the Galleria assay. 8-Methoxy-2,3-methylenedioxydibenz[b,e]oxepine, a hitherto undescribed fused heterocyclic ring system, was devoid of activity, indicating the importance of free rotation and/or molecular flexibility. In spite of the moderate activities of these compounds, the manifold biological potential of the quinone-methide mechanism justifies further research on these lines.  相似文献   

Panophthalmitis associated with diplococcic septicemia in a rhesus monkey     

P H Herman  J G Fox 《Journal of the American Veterinary Medical Association》1971,159(5):560-562

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Field evaluation of moxidectin/praziquantel oral gel in horses     

Grubbs ST  Amodie D  Rulli D  Wulster-Radcliffe M  Reinemeyer C  Yazwinski T  Tucker C  Hutchens D  Smith L  Patterson D 《Veterinary therapeutics : research in applied veterinary medicine》2003,4(3):249-256

The safety and efficacy of 2% moxidectin/12.5% praziquantel oral gel administered at a rate of 0.4 mg moxidectin and 2.5 mg praziquantel/kg was studied in client-owned horses under field use conditions. Four hundred horses (300 treated with moxidectin/praziquantel oral gel and 100 treated with vehicle) were enrolled, feces were collected, and eggs were counted. Investigators as well as horse owners were masked to treatment assignment. No adverse reactions to treatment were observed in any horses. Moxidectin/praziquantel gel reduced Anoplocephala spp by more than 99% and provided a significant (P <.05) reduction (> 98%) in the strongyle egg count of treated horses.  相似文献   

Good communication skills key to success          下载免费PDF全文

Hare D 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(8):621-622

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