Effect of Prophylactic Intramuscular Administration of Polysulfated Glycosaminoglycan on Developmental and Traumatic Joint Injuries in Thoroughbred Foals     

Gary W. White  G. Fredrick Fregin  Jules R. Selden 《Journal of Equine Veterinary Science》2007

The objective of this study was to determine whether a prophylactic regimen of intramuscular polysulfated glycosaminoglycans (PSGAG), administered to growing Thoroughbred foals, would significantly reduce the incidence or severity of osteochondritis dissecans (OCD) or traumatic joint lesions that had been found in untreated foals (historical controls) from the same farm during the preceding 3 years. The number of PSGAG-treated foals with clinically significant joint lesions was 44.1% lower than the number of foals with OCD/joint injuries that had been found in the untreated historical controls. Surgical intervention of the treated foals declined 87.7% from the incidence on the farm during the preceding 3 years. Although the incidence of OCD lesions of the hock, stifle, and fetlocks in treated foals was not significantly different from that found in the matched controls, the lesions in the PSGAG-treated foals resolved without surgery. These results suggest that PSGAG has the potential to improve the clinical course of osteochondrosis (OC) and OCD. Additional studies are underway to determine whether a shorter or more targeted prophylactic regimen will provide a similar benefit.  相似文献   

Population structure and regeneration status of Vitellaria Paradoxa (C. F. Gaertner) under different land management regimes in Atacora department,Benin     

Koutchoukalo Aleza  Kperkouma Wala  Jules Bayala  Grace B. Villamor  Marra Dourma  Wouyo Atakpama  Koffi Akpagana 《Agroforestry Systems》2015,89(3):511-523

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The increasing risk of Lyme disease in Canada     

Catherine Bouchard  Erin Leonard  Jules Konan Koffi  Yann Pelcat  Andrew Peregrine  Neil Chilton  Kateryn Rochon  Tim Lysyk  L. Robbin Lindsay  Nicholas Hume Ogden 《The Canadian veterinary journal. La revue veterinaire canadienne》2015,56(7):693-699

There is an increasing risk of Lyme disease in Canada due to range expansion of the tick vector, Ixodes scapularis. The objectives of this article are to i) raise public awareness with the help of veterinarians on the emerging and expanding risk of Lyme disease across Canada, ii) review the key clinical features of Lyme disease in dogs, and iii) provide recommendations for veterinarians on the management of Lyme disease in dogs.  相似文献   

Update on the 35‐year expansion of the invasive root pathogen,Phytophthora lateralis,across a landscape of Port Orford cedar (Chamaecyparis lawsoniana)          下载免费PDF全文

E. S. Jules  C. M. Steenbock  A. L. Carroll 《Forest Pathology》2015,45(2):165-168

Port Orford cedar (Chamaecyparis lawsoniana) is endemic to northern California and southwestern Oregon and is considered a foundation species that plays critical roles in riparian areas and on nutrient‐poor soils. Since 1952, a non‐native, pathogenic oomycete (Phytophthora lateralis) has been spreading throughout the range of the cedar. Most spread occurs by vehicles carrying infested soil along gravel roads primarily used for timber harvest. In a previous study conducted in 1998 and 1999, Port Orford cedar and P. lateralis were censused in a 37‐km² study area and dendrochronology was used to reconstruct the history of pathogen invasion. That work, which represents the only detailed analysis of spread rates for P. lateralis, showed that the first successful invasion into the study area took place in 1977 and that 43% of the susceptible host sites (stream crossings) were infested by 1999. In the work presented here, all sites that were uninfested in 1999 were re‐censused in 2012, extending the historical reconstruction of P. lateralis spread to 35 years. Two new infestations were initiated between 1999 and 2012, suggesting that the rate of spread of P. lateralis has slowed greatly. Between 1980 and 1989, the average number of new site infestations was 1.8 infestations per year, while between 1990 and 1999 the average was 0.4 infestations per year and between 2000 and 2009 the average was 0.2 infestations per year. Several potential explanations for the reduced number of new infestations are discussed.  相似文献   

Editorial     

Jules Bayala  Niéyidouba Lamien  Innocent Butare  Sibiri Jean Ouédraogo  Oscar Eyog-Matig 《New Forests》2011,41(3):277-279

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Defining the poor by the rural communities of Burkina Faso: implications for the development of sustainable parkland management     

Mamounata Belem  Jules Bayala  Antoine Kalinganire 《Agroforestry Systems》2011,83(3):287-302

Parklands are mixtures of trees and shrubs that farmers select for certain functions. In the Sahel, parklands are cultivated together with staple food crops, such as millet and sorghum. Parkland trees are sources of foods, including fruits, fats, oils, leafy vegetables, nuts and condiments that complement food crops in the local diet. Despite their socio-economic and ecological role, many studies have shown that the parklands are degrading very rapidly. Therefore, there is a need to undertake restoration actions that are based on a clear understanding of the livelihood context, such as the wealth status of the farmers, in which these agroecosystems are evolving. Thus, we conducted a wealth survey with rural communities in two different farming systems of Burkina Faso that are the cereal-based system in the “Plateau Central” and the cotton-based system in the “Boucle du Mouhoun”. A total of twelve villages were sampled, six villages for each system. The Participatory Analysis of Poverty and Livelihood Dynamics (PAPoLD) method was used by rural farmers to rank farmer households of their communities according to their wealth status. The results revealed that 70% of households in the Plateau Central and 56% in the “Boucle du Mouhoun” managed to escape poverty, and became wealthy. However, 2% of households of the villages in the Plateau Central and 6% in “Boucle du Mouhoun” fell into poverty in the same period whereas 9 and 12% remained poor in these zones, respectively. The main causes associated with households getting out of poverty are subsidies for cotton, external revenues from relatives working in towns and gardening activities. Death of spouse, illness, high number of people in the household and indebtedness are the main causes that lead into poverty. The implications of these findings in designing appropriate policies and management options for a sustainable management of agroforestry parklands under different land use systems were finally discussed.  相似文献   

Activation of Drosophila Toll during fungal infection by a blood serine protease   总被引：3，自引：0，他引：3  

Ligoxygakis P  Pelte N  Hoffmann JA  Reichhart JM 《Science (New York, N.Y.)》2002,297(5578):114-116

Drosophila host defense to fungal and Gram-positive bacterial infection is mediated by the Spaetzle/Toll/cactus gene cassette. It has been proposed that Toll does not function as a pattern recognition receptor per se but is activated through a cleaved form of the cytokine Spaetzle. The upstream events linking infection to the cleavage of Spaetzle have long remained elusive. Here we report the identification of a central component of the fungal activation of Toll. We show that ethylmethane sulfonate-induced mutations in the persephone gene, which encodes a previously unknown serine protease, block induction of the Toll pathway by fungi and resistance to this type of infection.  相似文献   

Global food supply. Linking policy on climate and food   总被引：1，自引：0，他引：1  

Godfray HC  Pretty J  Thomas SM  Warham EJ  Beddington JR 《Science (New York, N.Y.)》2011,331(6020):1013-1014

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The potential for soil carbon sequestration in three tropical dryland farming systems of Africa and Latin America: A modelling approach     

P.K. Farage  J. Ard  L. Olsson  E.A. Rienzi  A.S. Ball  J.N. Pretty 《Soil & Tillage Research》2007,94(2):457-472

Historically, agriculturally induced CO₂ release from soils has contributed to rising levels in the atmosphere. However, by using appropriate management, soils can be turned into carbon sinks. Many of the dryland regions of the world are characterised by degraded soils, a high incidence of poverty and a low capacity to invest in agriculture. Two well-proven soil organic matter models (CENTURY 4.0 and RothC-26 3) were used two explore the effects of modifying agricultural practices to increase soil carbon stocks. The changes to land management were chosen to avoid any significant increase in energy input whilst using technologies that would be available without radically altering the current agricultural methodology. Case studies were selected from dryland farming systems in Nigeria, Sudan and Argentina. Modelling showed that it would be possible to make alterations within the structure of the current farming systems to convert these soils from carbon sources to net sinks. Annual rates of carbon sequestration in the range 0.08–0.17 Mg ha⁻¹ year⁻¹ averaged over the next 50 years could be obtained. The most effective practices were those that maximised the input of organic matter, particularly farmyard manure (up to 0.09 Mg ha⁻¹ year⁻¹), maintaining trees (up to 0.15 Mg ha⁻¹ year⁻¹) and adopting zero tillage (up to 0.04 Mg ha⁻¹ year⁻¹). Verification of these predictions will require experimental data collected from field studies.  相似文献   

Regional Contamination in Lakes from the Noril'sk Region in Siberia,Russia     

Blais  Jules M.  Duff  Katharine E.  Laing  Tamsin E.  Smol  John P. 《Water, air, and soil pollution》1999,110(3-4):389-404

Sediment and water chemistry data were collected from ten lakes within a 110 km radius of Noril'sk in Siberia, the largest smelting complex in the world. Metals showing the most pronounced increase in enrichment near the smelters were Cu, Ni, Co, Ba and Zn. Cu and Ni appear to be as or more enriched in lake sediments around Noril'sk compared with levels previously reported for other locations. Although SO4 concentrations were highly elevated in the areas closest to the smelting complex, lake water pH remained elevated due to high concentrations of base cations in the waters. Sediment mercury enrichment was high in sediments near the smelting complex, but not more so than in other parts of the Arctic, suggesting that Hg either is not a major smelting product at Noril'sk, or that Hg is transported greater distances than other metals due to its longer atmospheric residence time.  相似文献