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An important problem of treating patients with endotoxemia is to find drugs to reduce the negative effects of endotoxin on the organism. We tested fucoidan (sulfated polysaccharide) from the brown alga Fucus evanescens as a potential drug in a mouse model of endotoxemia inducted by lipopolysaccharide (LPS). The survival time of mice injected with LPS increased under fucoidan treatment compared with the group of mice injected with LPS only. The preventive administration of fucoidan to mice with endotoxemia resulted in inhibition of increased levels of proinflammatory cytokines (TNFα and IL-6), as well as decreasing of the processes of hypercoagulability. The parenteral or per os administration of fucoidan resulted in decreasing the degree of microcirculatory disorders and secondary dystrophic-destructive changes in parenchymal organs of mice with endotoxemia. Taken together, these results demonstrate that fucoidan prevents endotoxin-induced damage in a mouse model of endotoxemia and increases the mice’s resistance to LPS.  相似文献   
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The effects of alkaline dust emitted from a cement plant for over 40 years on the anatomy of needles of Scots pine and lignin accumulation were analysed. Comparative analytical studies were conducted in stands similar as to their silvicultural indicators, climate and age in alkalised and in a relatively unpolluted area. Cross-section of needles were stained, photographed under microscope and measured. It was found that, due to the alkalisation of the environment, the total area of the needle cross-section, needle width and thickness and the area of mesophyll had decreased. At the same time, the vascular bundles and epidermis had increased. The greatest anatomical and biochemical differences between the needles from trees growing under optimum conditions and in the alkalised area were observed in the oldest needles. Visual analysis of cross-sections and biochemical analysis showed accumulation of lignin in older needles but more intensively in alkalised areas than in control.  相似文献   
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The dynamics of collembolan communities were investigated in a spruce forest and in a dry natural meadow (Moscow Region, Russia) from 1991 to 1998. The long-term dynamics of springtail communities were compared to understand the role of external and internal factors responsible for changes over time. The two springtail communities were similiar in species richness (54 and 52 species), species diversity, as well as their rank/dominance distribution patterns. There were two dominant species in the forest, Isotomiella minor (Schäff.) and Parisotoma notabilis (Schäff.), and three in the meadow, P. notabilis, Lepidocyrtus lignorum (Fabr.) and Protaphorura armata Gisin. Community organization was much more stable over time in the forest than in the meadow. Population densities of the two dominant species changed synchronously and correlated with mean monthly temperature in the forest. In the meadow, densities of only some dominant species (P. notabilis and L. lignorum) correlated with each other and with temperature. It is supposed that a constant organization of collembolan communities through time arises as a result of successional changes over long periods with relatively stable conditions allowing the gradual formation of complexes of dominant species.  相似文献   
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The influence of alkaline dust pollution (pH of water solution12.3–12.6) from a cement plant (Kunda, Estonia) and alkalizedgrowth substrate on lignin and mineral composition of the needles of 75–90-yr-old Norway spruce was studied on sample plots established at different distances from the emission source. Disbalanced content of nutrients and an increase in thelignin content were found under the high level of air pollution.The contents of K, Ca, S and B in needles were higher, while those of Mn and N were lower in heavily polluted plots. A strongcorrelation was found between lignin and K, N and B concentrations as well as Ca/K in needles and shoots. Stimulation of lignification of needles correlated with the pollution load. Reduction of needle growth was observed and a negative correlation was established between the lignin concentration in tissues and the length of needles under the impact of dust pollution.  相似文献   
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Carbonate concentrations in a chronosequence of paleosols buried under kurgans in the North Caucasus region at the end of the 4th century and the first half of the 5th century AD have been studied with the use of a set of morphological and isotopic methods. It is demonstrated that morphologically different phases of calcite—the collomorphic phase and the crystalline phase—in carbonate pedofeatures (calcareous pseudomycelium) and in the calcareous horizon have different elemental compositions and different isotopic compositions of carbon. Hence, these forms of calcite should have different origins. An addition of colloidal carbonates migrating in colloidal solutions from the lower soil horizons to the surface horizons during the periods of climatic aridization to the acicular calcite may be responsible for a sharp and irregular increase in the radiocarbon age of the newly formed carbonate pseudomycelium.  相似文献   
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The flux rates of carbon dioxide, methane, and nitrous oxide in the soils on autonomous, transitional, transitional-accumulative, and accumulative positions of a catena on the Oka River’s right bank (Moscow oblast) were assessed using the chamber method. The lowest rate of C-CO2 emission (18.8–29.8 mg/m2 per hour) was found for the gray forest soil in the autonomous position, and the highest rate (52.4–66.1 mg/m2 per hour) was found for the alluvial meadow soil of the accumulative landscape. In the summer, the uptake of methane from the atmosphere exceeded its release from the soil at all the points of the catena (9–38 μg/m2 per hour). The highest rate of the C-CH4 uptake was observed for the soil in the transitional position. In the fall, the soils in the autonomous, transitional, and transitional-accumulative positions served as a sink of C-CH4, and the soil of the accumulative position was a source of methane emission. The rate of the N-N2O emission from the catena soils increased when going from the autonomous position to the accumulative one (0.41–11.2 μg/m2 per hour). The spatial variation of the C-CO2, C-CH4, and N-N2O fluxes within the catena was 33, 172, and 138%, respectively. The upper (0- to 10-cm) soil layer made the major contribution to the emission of carbon dioxide. This soil layer was characterized by its C-CH4 uptake, and the emission of methane was typical for the deeper (0- to 20-cm) layer. The layers deeper than 10 and 20 cm emitted more N-N2O than the surface layer.  相似文献   
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It is known that brass is the construction material widely used when manufacturing agricultural equipment. An effective volatile inhibitor is offered to protect it from corrosion in the atmosphere of the livestock premises with 100% and close to it relative humidity of the air containing the stimulators of this process—CO2, NH3, H2S—in the concentrations that multiply exceed the background ones. A range of methods—weight corrosion tests and electrochemical measurements (potentiodynamic polarization, polarization resistance, fixed in the automatic mode)—define the conditions under which the inhibitors of the IFKHAN series multiply slow down the corrosion of brass. The general corrosion rate of L62 brass is decreased ten times in the presence of all studied inhibitors of this series in the atmosphere containing up to 20 mg/m3 of H2S and 100% relative humidity. It is most reasonable to use the IFKHAN-112 inhibitor with the ammonia content up to 30 mg/m3 in the maximum humid atmosphere.  相似文献   
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Eurasian Soil Science - We have evaluated the biological activity of brown semidesert soils (Eutric Cambisols (Loamic, Protocalcic)) of the Baer Knolls (Astrakhan oblast) formed under different...  相似文献   
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