排序方式： 共有6条查询结果，搜索用时 0 毫秒
1
1.
I.N.H. White R.D. Verschoyle M.H. Moradian J.M. Barnes 《Pesticide biochemistry and physiology》1976,6(5):491-500
The oral toxicity of 5-benzyl-3-furylmethyl-(1R, cis)-chrysanthemate (cismethrin) to female rats decreased as their environmental temperature was raised. Acute oral LD50 values increased from 157 mg/kg at 4°C to 197 mg/kg at 20°C and to > 1000 mg/kg at 30°C. Cismethrin was much more toxic given intravenously when the LD50 was 4.5 mg/kg. This value did not change at different environmental temperatures. Irrespective of the environmental temperature, or route of adminstration, following the respective LD50's cismethrin caused tremors in rats when brain levels of 0.5–1.0 μg/g were reached and, at death, brain concentrations were 3.9–5.1 μg/g. These results suggested that the accumulation of cismethrin by the brain could be used as a model for the nervous system as a whole. The isomeric 5-benzyl-3-furylmethyl-(1R, trans)-chrysanthemate (bioresmethrin) was about 50 times less toxic to rats than cismethrin. After an intravenous LD50, tremors started when brain concentrations were 4–5 μg/g. At death, brain levels were 25–35 μg/g. Plasma esterases were about equally active in hydrolysing cismethrin and bioresmethrin, whereas liver microsomal esterases hydrolyzed bioresmethrin over 10 times more rapidly than cismethrin. It is suggested that the lower toxicity of bioresmethrin is not only due to its faster metabolism but to an intrinsically lower toxicity at the critical site of action in the nervous system. 相似文献
2.
Alizadeh Fatemeh Moradian Fatemeh Farhadi Ayoub 《Tropical animal health and production》2020,52(6):3027-3034
Insulin-like growth factor-binding protein acid-labile subunit (IGFALS) encodes a protein which binds to IGF1 and IGFBP-3 to regulate the growth, differentiation, and other physiological processes. The aim of this study was the identification of allelic polymorphisms of the IGFALS gene using the PCR-RFLP technique and evaluation of their association with growth traits. For this end, 120 blood samples were randomly collected from each breed. Following amplification of an 1113-bp fragment of exon 1 and a part of intron 1 of the IGFLAS gene, genotyping was conducted by three restriction enzymes including HinfI, MscI, and PvuII. The results showed that only one allele was observed in IGFALS-PvuII site, while in IGFLAS-MscI site, three AA, AB, and BB genotypes with the frequencies of 17.5%, 32%, and 50.5% and 11%, 37.5%, and 51.5% were observed in Makouei and Ghezel sheep breeds, respectively. Additionally, in the IGFLAS-HinfI site, two AB and BB genotypes with the frequency of 34.2% and 65.8% were observed in Makouei sheep and AA, AB, and BB genotypes with the frequency of 9%, 21%, and 70% were observed in Ghezel sheep. So that, Makouei sheep with AB genotype had more chest girth (CG) compared with other genotypes. Furthermore, a significant association was observed between the genotypes of IGFLAS-HinfI with birth weight (BW) in Ghezel and BW, weaning weight (BW3), and CG in Makouei sheep. Haplotype analysis revealed an association between paternal haplotypes and BW in both Ghezel and Makouei breeds. So that, AAB and ABB haplotypes showed more BW than others in Makouei and Ghezel sheep, respectively.
相似文献3.
Mazeyar Parvinzadeh Gashti Siamak Moradian Abosaeed Rashidi Mohamad-Esmail Yazdanshenas 《Fibers and Polymers》2013,14(5):743-751
Poly(ethylene terephthalate) [PET] based nanocomposites containing three differently modified silica particles were prepared by melt compounding. The influence of type of nano-silica on dispersibility, thermal and dyeing properties of the resultant nanocomposite was investigated by various analytic techniques, namely, polarized optical microscopy (POM), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), reflectance spectroscopy (RS), and light fastness. Optical microscopy images illustrated that nano-silica particles tended to increase the number of spherulites in the PET matrix which were dependent on nano-silica type and content. Thermal studies of the resultant nanocomposites showed a slight decrease in the melting temperature compared to a pristine PET. Silica nanocomposites were finally dyed with a disperse dye and their reflectances were determined by the aid of reflectance spectrophotometer. Such reflectances were converted to the corresponding color coordinate values which are indicative of dyeability of such nanocomposites. 相似文献
4.
Single and combined infections of specific-pathogen-free chickens with infectious bursal disease virus and an intestinal isolate of reovirus 总被引：2，自引：0，他引：2
The susceptibility of 1-day-old and 7-day-old specific-pathogen-free chickens to infection with a virulent strain of infectious bursal disease virus (IBDV) or an intestinal isolate of avian reovirus, or a combination of the two, was investigated. Chickens infected with IBDV and reovirus had more severe pathological lesions than chickens infected with either virus alone, and prior infection with IBDV enhanced the pathogenicity of enteric reovirus. Virus recovery was attempted from bursa, spleen, thymus, liver, intestine, pancreas, cecal tonsils, heart, and tarso-metatarsal tendons. Viruses were recovered from all tissues sampled for either IBDV or reovirus isolation, and indications were that infection with IBDV before infection with reovirus led to longer persistence of reovirus in some tissues. Antibodies to IBDV or reovirus were measured by the virus neutralization test and enzyme-linked immunosorbent assay. Chickens infected with IBDV had lower (P less than 0.05) antibody responses to reovirus than chickens infected with reovirus alone. 相似文献
5.
Mohammadali Saadatnia Aliakbar Enayati Kambiz Pourtahmasi Mohammadhadi Moradian 《Wood material science & engineering》2016,11(4):201-208
Transversal variations of some ultrasound wave parameters (phase velocity, group velocity, attenuation coefficient and acoustic radiation) were measured from the pith to the bark of poplar tension wood discs in different orthotropic directions. Over 80 cubic specimens of 2 × 2 × 10 cm3 (radial, tangential and longitudinal, respectively) were prepared and tested acoustically. Samples containing tension woods were separated from normal ones using anatomical experiments. Results showed acoustical behaviour of normal and tension wood improved in longitudinal direction while the distance between pith and bark increased; also, wave parameter variations were less important in radial and tangential directions. In addition, phase velocity and acoustic radiation – which significantly varied – were the best parameters for quality assessment of poplar wood compared with group velocity and attenuation coefficients. Since samples near the bark were acoustically better than counterparts near the pith, they could be used in products requiring more strength, like lumber. Finally, acoustic radiation and phase velocity were correlated more strongly with density than group velocity and attenuation. 相似文献
6.
Effects of dietary bovine lactoferrin on growth,haemato‐biochemical parameters,immune functions and tolerance to air exposure stress in the African cichlid Sciaenochromis fryeri 
下载免费PDF全文
下载免费PDF全文 The effects of dietary bovine lactoferrin (LF) on the growth, haemato‐biochemical parameters, non‐specific serum immunity and stress responses were investigated in the African cichlid, Sciaenochromis fryeri. Four isocaloric diets containing 0 (control), 200, 400 and 800 mg LF kg?1 diet were formulated and fed to juvenile fish for 8 weeks. The treatments had no effects on the survival rate, growth performance or haematological parameters. Nor were the serum levels of total protein, albumin and globulin significantly influenced. Serum iron levels and total iron binding capacity (TIBC), however, changed vigorously as the result of dietary LF. Dietary LF led to significant reductions in serum levels of alanine transaminase and alkaline phosphatase. The highest lysozyme and bactericidal activities were observed in the fish fed the diets with 200 and 800 mg/kg of LF, respectively, while no changes were observed in their ACH50 levels. Recovery rates were measured after 10 min of air exposure stress. The rate was about twice higher (36% vs 20%) in fish fed on 400 mg LF than in those fed the control diet. Results revealed that adding 400 mg/kg LF could be beneficial as an iron discriminator, for liver function as well as an immune and stress resistance promoter. 相似文献
1