排序方式： 共有16条查询结果，搜索用时 15 毫秒
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Andrzej Pedryc Szabolcs Ruthner Rita Hermán Boris Krska Attila Hegedűs Júlia Halász 《Scientia Horticulturae》2009
Eight polymorphic simple sequence repeat (SSR) markers located in the G1 linkage group of apricot (Prunus armeniaca L.) were previously developed and evaluated in a small set of cultivars. Those primers were used for studying variability in 77 apricot cultivars belonging to five different geographical groups, such as Chinese, Asian (Irano-Caucasian and Central Asian), North American, Mediterranean and Western European as well as Middle European cultivars. Six of the markers were polymorphic and revealed a total of 71 alleles ranging from 5 (aprigms11) to 20 (aprigms1) alleles per locus with a mean value of 11.83 alleles per locus. In conclusion, the SSR loci located in the G1 linkage group show a level of polymorphism which is similar to loci dispersed throughout the entire genome. The total number of alleles and the number of unique alleles were the highest in Chinese apricots and the lowest in Middle European cultivars. Heterozygosity also showed a decrease from Asia and China to Middle Europe. No association could have been observed between any SSR markers tested and plum pox virus (PPV) resistant phenotype of cultivars. PPV resistant cultivars did not form a separate clade on the dendrogram obtained by UPGMA cluster analysis. Middle European and Chinese cultivars formed separate clusters while other genotypes formed smaller multiple sub-groups or scattered among different clusters. Our results support previous hypotheses on the origin of PPV resistance in North American apricots. The allele data was also presented in a form that allowed the easy observation of allele frequencies in each geographical group at each locus. Using this data field, differences and similarities between cultivar groups can be easily assessed. The analysis demonstrated the links between the North American and Mediterranean apricot germplasm and confirmed that the Chinese and Eastern European cultivars are distantly related. 相似文献
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Seasonal changes in testis volume, testosterone (T) productivity (GnRH test) and semen characteristics of Mangalica boars were studied. The biggest testis volume was measured in autumn and the smallest in winter. Significant differences were demonstrated between autumn-winter (P = 0.012) and autumn-spring (P = 0.015) in testis volume. The highest basic T concentration (Tb) was observed in autumn and the lowest in summer. The provoked T concentration (Tincr) was significantly higher in autumn than in spring (P = 0.0007). A strong correlation was observed between T concentrations and testis volume in spring. The highest ejaculate volume was measured in winter while the lowest in autumn. Significant differences were found in semen concentration as well as in the total number of spermatozoa per ejaculate between seasons. The highest number of abnormal sperm cells was observed in spring while the lowest in summer. It can be concluded that the ejaculate of the Mangalica breed tends to be of lower volume and higher sperm concentration as compared to most pig breeds. Seasonal differences could be observed in testicular measurements, testosterone production capacity and sperm morphological features; however, sperm motility remained constantly high during the study. 相似文献
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Shakya R Reid LJ Reczek CR Cole F Egli D Lin CS deRooij DG Hirsch S Ravi K Hicks JB Szabolcs M Jasin M Baer R Ludwig T 《Science (New York, N.Y.)》2011,334(6055):525-528
Germline mutations of the breast cancer 1 (BRCA1) gene are a major cause of familial breast and ovarian cancer. The BRCA1 protein displays E3 ubiquitin ligase activity, and this enzymatic function is thought to be required for tumor suppression. To test this hypothesis, we generated mice that express an enzymatically defective Brca1. We found that this mutant Brca1 prevents tumor formation to the same degree as does wild-type Brca1 in three different genetically engineered mouse (GEM) models of cancer. In contrast, a mutation that ablates phosphoprotein recognition by the BRCA C terminus (BRCT) domains of BRCA1 elicits tumors in each of the three GEM models. Thus, BRCT phosphoprotein recognition, but not the E3 ligase activity, is required for BRCA1 tumor suppression. 相似文献
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Máté Havasi Tamás Oláh Zoltán Felföldi Szabolcs Nagy Miklós Bercsényi 《Aquaculture International》2013,21(4):861-867
Passing times of two different types of feeds were determined in cases of wels (Silurus glanis) by measuring the body weight at three different temperatures. Fingerlings, 38.03 ± 8.04 g, were fed by an artificial dry feed (commercial catfish feed) or forage fish. The treatments were carried out (11 fish/aquaria) in 3 replicates. Fish were individually tagged by pit tags. Temperatures applied were the following: 15, 20 and 24 °C. The appetite of fish highly depended on temperature. At 15 °C, only 42.4 % of the experimental fish accepted the granulated feed, while this ratio was 90.9 % in the forage fish fed group. At higher temperatures, 100 % of the experimental fish accepted feed in both feeding groups. The daily mean value of consumed feed at 15 °C was 3.20 % of body weight in the case of forage fish and 1.36 % in the case of dry feed. At 24 °C, this ratio was 10.68 % of body weight in cases of forage fish and 4.46 % in cases of artificial feed. At low temperature (15 °C), the quantity of consumed feed met the measurement’s error threshold, which made the determination of passing time uncertain. At 20 °C, the evacuation started 20 h after feeding and lasted for 18 h, while at 24 °C, it started 11 h after feeding and lasted for another 16 h. 相似文献
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Andrea Balázs Magdolna Tóth Balázs Blazics Éva Héthelyi Szabolcs Szarka Emese Ficsor Gitta Ficzek Éva Lemberkovics Anna Blázovics 《Fitoterapia》2012
Three red-fleshed apple cultivars (Malus ‘Geneva’: GFV-03, Hungarian hybrid: GFV-04, Malus pumila Niedwetzkyana: GFV-05) were investigated for their chemical composition by sHS–SPME–GC–MS and HPLC–DAD–MS/MS analytical techniques. 相似文献
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Mari Friman Leila Kakko Camelia Constantin Heli Simojoki Maria A. Andersson Szabolcs Nagy Heidi Salonen Magnus Andersson 《Reproduction in domestic animals》2019,54(9):1279-1283
Bacillus anthracis infecting cattle is usually identified based on the typical symptom: sudden death. Bacillus anthracis causing atypical symptoms may remain undiagnosed and represent a potential occupational health hazard for, that is veterinarians and producers, butchers and tanners. In the year 2004, one case of sudden death in a dairy farm in southern Finland was diagnosed as bovine anthrax. Four years later 2008, an atypical case of anthrax was diagnosed in the same holding. The bull was taken to the Production Animal Hospital of the Faculty of Veterinary Medicine, University of Helsinki because of fever, loss of appetite and a symmetrically swollen scrotal sac. Penicillin treatment cured the fever but not the swollen scrotum. Before the intended therapeutic castration, a punctuate consisting of 10 ml fluid collected into a syringe from the scrotal sac was cultivated on blood agar at 37°C. After 24 hr, an almost pure culture of a completely non‐hemolytic Bacillus cereus‐like bacteria was obtained. The strain was identified as B. anthracis using Ba‐specific primers by the Finnish Food Safety Authority (RUOKAVIRASTO). After the diagnosis, the bull was euthanized and destroyed, the personnel were treated with prophylactic antibiotics and the clinic was disinfected. In this particular case, treatment with water, Virkon S and lime seemed to be effective to eliminate endospores and vegetative cells since no relapses of anthrax have occurred in 10 years. This case is the last reported anthrax case in Finland. 相似文献
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Szabadics J Varga C Molnár G Oláh S Barzó P Tamás G 《Science (New York, N.Y.)》2006,311(5758):233-235
Axons in the cerebral cortex receive synaptic input at the axon initial segment almost exclusively from gamma-aminobutyric acid-releasing (GABAergic) axo-axonic cells (AACs). The axon has the lowest threshold for action potential generation in neurons; thus, AACs are considered to be strategically placed inhibitory neurons controlling neuronal output. However, we found that AACs can depolarize pyramidal cells and can initiate stereotyped series of synaptic events in rat and human cortical networks because of a depolarized reversal potential for axonal relative to perisomatic GABAergic inputs. Excitation and signal propagation initiated by AACs is supported by the absence of the potassium chloride cotransporter 2 in the axon. 相似文献
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Szabó-Hevér Ágnes Lehoczki-Krsjak Szabolcs Varga Mónika Purnhauser László Pauk János Lantos Csaba Mesterházy Ákos 《Euphytica》2014,200(1):9-26
The genetic background of Fusarium head blight (FHB) resistance in the moderately resistant wheat variety Frontana was investigated in the GK Mini Manó/Frontana DH population (n = 168). The plant material was evaluated across seven epidemic environments for FHB, Fusarium-damaged kernel (FDK) and deoxynivalenol (DON) contents caused by two Fusarium species (F. culmorum and F. graminearum). The effects of phenotypic traits such as plant height and heading date were also considered in the experiments. In the population, 527 polymorph markers (DArT, SSR) within a distance of 1,381 cM distance were mapped. The quantitative trait locus/loci (QTL) on chromosomes 4A and 4B demonstrated a significant linkage only with FHB, while QTL on chromosomes 3A, 4B, 7A and 7B were linked to DON accumulation alone. Regions determining all the investigated Fusarium resistance traits were identified on chromosomes 1B, 2D, 3B, 5A, 5B and 6B. The markers in these regions are of the greatest significance from the aspect of resistance breeding. Our results indicate that the genetic background of resistance against FHB, FDK and DON accumulation can differ, and all these traits should be taken under consideration during resistance tests. Moreover, this is the first report on the mapping of Frontana-derived QTL that influence DON accumulation, which is important since the level of DON contamination determines the actions of the food and feed industries. Selection should therefore also focus on this trait by using molecular markers linked to DON content. 相似文献
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