Lymphangiosarcoma in 12 dogs: a case series (1998–2013)          下载免费PDF全文

K. M. Curran  C. H. C. Halsey  D. R. Worley 《Veterinary and comparative oncology》2016,14(2):181-190

Lymphangiosarcoma (LAS) is an uncommon malignant neoplasia arising from lymphatic endothelium; little information exists regarding therapy. Single institutional retrospective review for canine LAS histopathology diagnoses over a 15‐year period yielded 12 dogs. Ten dogs were presented for a mass and/or swelling at cervical, trunk or limb regions. Prior to diagnosis, 10 dogs received empiric wound therapy. Cytology performed in 10 consisted of mild inflammation. Survival ranged from 60, 168 and 876 days for three dogs with palliation; 90 days with prednisone in one; 182 days with chemotherapy in one; 240, 267, 487, 630 and 941 days for five receiving surgery; and 574 days for one receiving surgery, radiation and chemotherapy. One dog is alive with recurrence at 243 days following surgery and carboplatin chemotherapy. Clinical improvement existed in LAS dogs receiving multimodal therapies. Early tissue biopsies are recommended for progressive oedematous lesions of unknown origin.  相似文献   

Impact of El Nino and logging on canopy tree recruitment in borneo     

Curran LM  Caniago I  Paoli GD  Astianti D  Kusneti M  Leighton M  Nirarita CE  Haeruman H 《Science (New York, N.Y.)》1999,286(5447):2184-2188

Dipterocarpaceae, the dominant family of Bornean canopy trees, display the unusual reproductive strategy of strict interspecific mast-fruiting. During 1986-99, more than 50 dipterocarp species dispersed seed only within a 1- to 2-month period every 3 to 4 years during El Nino-Southern Oscillation events. Synchronous seed production occurred across extensive areas and was essential for satiating seed predators. Logging of dipterocarps reduced the extent and intensity of these reproductive episodes and exacerbated local El Nino conditions. Viable seed and seedling establishment have declined as a result of climate, logging, and predators. Since 1991, dipterocarps have experienced recruitment failure within a national park, now surrounded by logged forest.  相似文献   

Effect of cereal type and exogenous enzyme supplementation in pig diets on odour and ammonia emissions     

B.P. Garry  M. Fogarty  T.P. Curran  J.V. O''Doherty   《Livestock Science》2007,109(1-3):212-215

A 2 × 2 factorial experiment was conducted to investigate the interaction between cereal type (wheat vs. barley) and exogenous enzyme supplementation (with or without) on odour concentration and ammonia emissions in grower–finisher pigs. The enzyme supplement used contained Endo-1, 3 (4)-β-glucanase (EC 3.2.1.6) and Endo-1, 4-β-xylanase (E.C 3.2.1.8). The diets were formulated to contain similar levels of digestible energy and lysine. The experimental treatments were as follows: (1) wheat-based diet, (2) wheat-based diet containing a β-glucanase and β-xylanase mixed enzyme supplement, (3) barley-based diet and (4) barley-based diet containing a β-glucanase and β-xylanase mixed enzyme supplement. The diets were offered to the pigs for 4 weeks and this was repeated 4 times (n = 4). Odour and ammonia emissions were measured on days 9, 11, 14, 16, 21 and 23 of each experimental period. Odour samples were collected in 20-litre Nalophan bags and analysed for odour concentration using an ECOMA Yes/No Olfactometer. Ammonia concentrations were measured using Dräger tubes. There was a cereal × enzyme interaction in odour emission rates (P < 0.05) and in ammonia emissions (P < 0.01). The addition of an enzyme supplement increased odour emissions and had no effect on ammonia emissions in the barley-based diet. The enzyme supplementation had no effect on odour but decreased ammonia emissions in the wheat based diet.  相似文献   

Chicken anemia agent: an electron microscopic study   总被引：4，自引：0，他引：4  

M S McNulty  W L Curran  D Todd  D P Mackie 《Avian diseases》1990,34(3):736-743

Particles of chicken anemia agent (CAA) negatively stained with uranyl acetate were found to be 26.5 nm in diameter. The surface detail evident on the particles indicated that the virus capsid was composed of 32 structural subunits arranged as in a class P = 3 icosahedron with a triangulation number of 3. Using mouse monoclonal antibodies to CAA and a gold-labeled goat anti-mouse IgG, CAA-specific structures were observed by thin-section electron microscopy in infected MDCC-MSB1 cells and in thymic lymphocytes from experimentally infected chicks. These consisted of electron-dense, granular, non-membrane-bound nuclear inclusions, which were often ring-shaped, and cytoplasmic accumulations of microtubules. Aggregates of virus-like particles were sometimes observed in the nuclei of infected MDCC-MSB1 cells. The nucleolar involvement that is characteristic of the morphogenesis of parvoviruses was not observed with CAA.  相似文献   

Use of middle infrared radiation to estimate the leaf area index of a boreal forest     

Boyd DS  Wicks TE  Curran PJ 《Tree physiology》2000,20(11):755-760

The leaf area index (LAI) of boreal forest can be estimated using reflected radiation recorded by satellite sensors. Measurements of visible and near infrared radiation are commonly used in the normalized difference vegetation index (NDVI) to estimate LAI. However, research, mainly in tropical forest, has demonstrated that LAI is related more closely to radiation of middle infrared wavelengths than of visible wavelengths. This paper derives a vegetation index, VI3, based on radiation from vegetation recorded at near and middle infrared wavelengths. For a boreal forest canopy, the relationship between VI3 and LAI was observed to be much stronger than that between NDVI and LAI. In addition, the LAI estimated using VI3 accounted for about 76% of the variation in field estimates of LAI, compared with about 46% when using the NDVI. We conclude that information provided by middle infrared radiation should be considered when estimating the leaf area index of boreal forest.  相似文献   

Vertical movements of bigeye tuna (Thunnus obesus) associated with islands, buoys, and seamounts near the main Hawaiian Islands from archival tagging data   总被引：5，自引：0，他引：5  

Michael K. Musyl  Richard W. Brill  Christofer H. Boggs  Daniel S. Curran  Thomas K. Kazama  Michael P. Seki 《Fisheries Oceanography》2003,12(3):152-169

To learn more about the movement patterns of bigeye tuna (Thunnus obesus), we deployed archival tags on 87 fish ranging in fork length from 50 to 154 cm. Thirteen fish were recaptured, from which 11 archival tags were returned, representing in aggregate 943 days‐at‐liberty. We successfully retrieved data from 10 tags, representing 474 days in aggregate. The largest fish recaptured was 44.5 kg [131 cm fork length (FL)] and the smallest 2.8 kg (52 cm). The deepest descent recorded was 817 m, the coldest temperature visited 4.7°C, and minimum oxygen level reached ～1 mL L^?1. Fish spent little time at depths where water temperatures were below 7°C and oxygen levels less than ～2 mL L^?1. Five fish were recaptured near the offshore weather buoy where they were tagged. Based on vertical movement patterns, it appeared that all stayed immediately associated with the buoy for up to 34 days. During this time they remained primarily in the uniform temperature surface layer (i.e. above 100 m). In contrast, fish not associated with a floating object showed the W‐shaped vertical movement patterns during the day characteristic of bigeye tuna (i.e. descending to ～300–500 m and then returning regularly to the surface layer). Four fish were tagged and subsequently recaptured near Cross Seamount up to 76 days later. These fish exhibited vertical movement patterns similar to, but less regular than, those of fish not associated with any structure. Bigeye tuna appear to follow the diel vertical movements of the deep sound scattering layer (SSL) organisms and thus to exploit them effectively as a prey resource. Average night‐time depth was correlated with lunar illumination, a behaviour which mimics movements of the SSL.  相似文献   

Fluorous mixture synthesis: a fluorous-tagging strategy for the synthesis and separation of mixtures of organic compounds     

Luo Z  Zhang Q  Oderaotoshi Y  Curran DP 《Science (New York, N.Y.)》2001,291(5509):1766-1769

The solution-phase synthesis of organic compounds as mixtures rather than in individual pure form offers efficiency advantages that are negated by the difficulty in separating and identifying the components of the final mixture. Here, a strategy for mixture synthesis that addresses these separation and identification problems is presented. A series of organic substrates was tagged with a series of fluorous tags of increasing fluorine content. The compounds were then mixed, and multistep reactions were conducted to make enantiomers or analogs of the natural product mappicine. The resulting tagged products were then demixed by fluorous chromatography (eluting in order of increasing fluorine content) to provide the individual pure components of the mixture, which were detagged to release the final products.  相似文献   

Ice core evidence for Antarctic sea ice decline since the 1950s     

Curran MA  van Ommen TD  Morgan VI  Phillips KL  Palmer AS 《Science (New York, N.Y.)》2003,302(5648):1203-1206

The instrumental record of Antarctic sea ice in recent decades does not reveal a clear signature of warming despite observational evidence from coastal Antarctica. Here we report a significant correlation (P < 0.002) between methanesulphonic acid (MSA) concentrations from a Law Dome ice core and 22 years of satellite-derived sea ice extent (SIE) for the 80 degrees E to 140 degrees E sector. Applying this instrumental calibration to longer term MSA data (1841 to 1995 A.D.) suggests that there has been a 20% decline in SIE since about 1950. The decline is not uniform, showing large cyclical variations, with periods of about 11 years, that confuse trend detection over the relatively short satellite era.  相似文献   

Monitoring the U.S. AIDS epidemic     

R Berkelman  J Curran  W Darrow  T Dondero  M Morgan 《Science (New York, N.Y.)》1989,245(4921):908-910

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Comparison of methods for diagnosis of rotavirus infection of calves.     

M S McNulty  G M Allan  W L Curran  J B McFerran 《The Veterinary record》1976,98(23):463-464

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