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1.
The aim of this study was to investigate the effects of treatment with medroxyprogesterone acetate (MPA) on canine adenohypophyseal function. Five Beagle bitches were treated with MPA (10mg/kg, every 4 weeks) and their adenohypophyseal function was assessed in a combined adenohypophyseal function test. Four hypophysiotropic hormones (CRH, GHRH, GnRH, and TRH) were administered before and 2, 5, 8, and 11 months after the start of MPA treatment, and blood samples for determination of the plasma concentrations of ACTH, cortisol, GH, IGF-1, LH, FSH, prolactin, alpha-MSH, and TSH were collected at -15, 0, 5, 10, 20, 30, and 45 min after suprapituitary stimulation. MPA successfully prevented the occurrence of estrus, ovulation, and a subsequent luteal phase. MPA treatment did not affect basal and GnRH-induced plasma LH concentrations. The basal plasma FSH concentration was significantly higher at 2 months after the start of MPA treatment than before or at 5, 8, and 11 months after the start of treatment. The maximal FSH increment and the AUC for FSH after suprapituitary stimulation were significantly higher before treatment than at 5, 8, and 11 months of MPA treatment. Differences in mean basal plasma GH concentrations before and during treatment were not significant, but MPA treatment resulted in significantly elevated basal plasma IGF-1 concentrations at 8 and 11 months. MPA treatment did not affect basal and stimulated plasma ACTH concentrations, with the exception of a decreased AUC for ACTH at 11 months. In contrast, the maximal cortisol increment and the AUC for cortisol after suprapituitary stimulation were significantly lower during MPA treatment than prior to treatment. MPA treatment did not affect basal plasma concentrations of prolactin, TSH, and alpha-MSH, with the exception of slightly increased basal plasma TSH concentrations at 8 months of treatment. MPA treatment did not affect TRH-induced plasma concentrations of prolactin and TSH. In conclusion, the effects of chronic MPA treatment on adenohypophyseal function included increased FSH secretion, unaffected LH secretion, activation of the mammary GH-induced IGF-I secretion, slightly activated TSH secretion, suppression of the hypothalamic-pituitary-adrenocortical axis, and unaffected secretion of prolactin and alpha-MSH.  相似文献   
2.
深松耕作对土壤水分物理特性及作物生长的影响   总被引:18,自引:0,他引:18  
通过对两种土壤深松耕作及传统耕作的对比试验研究,表明深松耕作可有效打破犁底层,使土壤容重降低0.1t/m3,孔隙度增大3.6%~4.0%,110cm上体内可多蓄纳雨水15.2~17.5mm。对粘壤上深松耕作可提高土壤的入渗能力,而对粉砂壤土则没有提高。同传统耕作相比,深松耕作可明显提高夏玉米的根长、根深及根量,为有效利用土壤水分及养分创造了条件.可使夏玉米产量提高5.7%~11.3%。  相似文献   
3.
做好农村供水工程水质检测工作对保障农村供水水质安全至关重要,但它同时也是农村供水的薄弱环节,针对如何建立农村供水工程的水质检测模式开展研究与探讨。明确了农村供水工程水质检测的目标任务,分析了当前农村供水工程水质检测的现状与存在问题,从水质检测指标的选择、水质检测项目与频率的确定、水质检测设备的配备、水质检测人员的配置和监管、水质检测反馈机制的构建等几个方面提出了构建农村供水工程水质检测模式的建议,以期帮助提高农村供水工程的水质检测能力,保障农村供水水质安全。  相似文献   
4.
Horses need to be sedated before they are investigated by transcranial magnetic stimulation because of the mild discomfort induced by the evoked muscle contraction and the noise of stimulation. This paper describes the influence of a combination of detomidine (10 microg/kg bodyweight) and a low dose of buprenorphine (2.4 microg/kg) on the onset latency and peak-to-peak amplitude of magnetic motor-evoked potentials in normal horses. There were no significant differences between measurements of these parameters made before the horses were sedated and measurements made 10 and 30 minutes after the drugs were administered.  相似文献   
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第四章 工程修复或现代化改造  项目的制定4.1 方案的论证和制定下一个阶段 ,要根据历史背景资料及已做出的诊断评估 ,确定修复或现代化改造项目可能包括的工程范围。其方案从来就不是唯一的 ,而是要在对项目的自然条件、投资情况、目标优先顺序、组织机构改造及用户响应情况进行分析之后 ,制定出多个颇有差别的方案 ,然后通过认真比较、筛选 ,最终选择出一个方案。例如埃及灌溉工程改进 (IIP)的现代化改造程序 :在埃及水管理研究所 (EgyptWaterManagementResearchIn stitute)撰写的一份特别报…  相似文献   
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<正> 排水暗管管材经历了不断发展、更新及完善的过程。在五十年代以前,粘土管和砼管是各国所使用的最主要的排水管材。目前,国外粘土管的质量已达到较高的程度。六十年代以来,随着塑料工业的发展,暗管排水材料又增加了塑料排水管这一新品种,尤其是波纹塑料排水管的出现及铺设安装的机械  相似文献   
9.
Kentville 研究中心最近对肉用禽使用系列抗菌素生长促进剂重新进行了实验评价,其结果如下。生长促进剂这一术语是指在全价饲粮中添加少量的某些抗菌素对青年畜禽的促进生长的作用。1949年发表了关于抗菌素生长促进作用的科学论文,该论文论述了氯四环素对鸡的促生长作用。此后,许多抗菌素相继被作为生长促进剂。然而由于近年来商品鸡群在遗传基因,管理上有了很大变化,所以加拿大 Kentville 研究中心对使用抗菌素作为肉禽的生长促进剂重新进行了实验评价。  相似文献   
10.
Transcranial magnetic stimulation and measurement of the magnetic motor-evoked potentials (MMEPs) in the thoracic and pelvic limbs of four recumbent horses and one recumbent donkey were used to assess the integrity of the descending motor pathways, in order to confirm or exclude a descending motor tract lesion as the cause of the recumbency. In two of the animals abnormal MMEPs were recorded; in one of the horses a lesion along the cervical spinal cord due to a fracture of the fifth cervical vertebra was diagnosed and confirmed by radiography and postmortem examination; in another horse, damage to the peripheral nerves of the left forelimb was diagnosed and confirmed postmortem when a large abscess was found to have been compressing the peripheral nerves at the level of the last cervical vertebra. In the three other animals, normal MMEPs were recorded, and laminitis, rhabdomyolysis and physitis were diagnosed as the causes of the recumbency.  相似文献   
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