Evaluation of the influence of atipamezole on the postoperative analgesic effect of buprenorphine in cats undergoing a surgical ovariohysterectomy          下载免费PDF全文

Leon N Warne  Thierry Beths  Jennifer E Carter  Ted Whittem  Sébastien H Bauquier 《Veterinary anaesthesia and analgesia》2016,43(4):424-428

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Adrenomedullin (AM) and adrenomedullin binding protein (AM-BP) in the bovine mammary gland and milk: Effects of stage of lactation and experimental intramammary E. coli infection     

Elsasser TH  Capuco AV  Caperna TJ  Martínez A  Cuttitta F  Kahl S 《Domestic animal endocrinology》2007,32(2):138-154

Adrenomedullin (AM) has been characterized as an endogenous tissue survival factor and modulator of many inflammatory processes. Because of the increased susceptibility of the mammary gland to infection during the time surrounding parturition in the cow, we investigated how milk and tissue content of AM and its binding protein (AM-BP) might be affected by the stage of lactation and the udder health status. Milk and mammary biopsy samples were obtained from Holstein cows 21 days prior to and at various times after calving to represent the dry period and early and mid-stages of lactation. Additional cows received an intramammary challenge with Escherichia coli for immunohistochemical characterization of AM and AM-BP. Milk AM concentrations were relatively constant across the stages of lactation while AM-BP increased two-fold (P<0.04) between early and mid-lactation. Milk AM (P<0.04) and AM-BP (P<0.03) increased as somatic cell counts (SCCs) increased within a given stage of lactation. Tissue content of both (AM and AM-BP) were significantly affected by stage of lactation, lowest in the dry period and progressively increasing to peak at mid-lactation as well as increasing in association with higher levels of SCCs. Following E. coli challenge, AM increased in epithelial cells surrounding mammary alveoli presenting high levels of SCCs. The data suggest that AM and AM-BP are cooperatively regulated in the mammary gland during lactation; changes in localized tissue AM and AM-BP content reflect a dynamic regulation of these tissue factors in the bovine mammary gland consistent with their protective effects within inflamed tissue.  相似文献   

Symmetrical alopecia, scaling and hepatitis in a rabbit   总被引：2，自引：1，他引：1  

Florizoone K  van der Luer R  van den Ingh T 《Veterinary dermatology》2007,18(3):161-164

A 5-year-old rabbit with inappetence, symmetrical alopecia and skin lesions was examined. No mites or Malassezia were found in skin scrapings and tape impressions and dermatophyte culture was negative. Trial therapy with ivermectin did not reduce skin lesion severity, and euthanasia was performed because of anorexia after 1 month. Histopathology of the skin showed hyperkeratosis, lymphocytic exocytosis, cell-poor interface dermatitis (lymphocytic infiltration and apoptotic cells in basal layer of epidermis), absence of sebaceous glands and lymphocytic mural folliculitis comparable to sebaceous adenitis and thymoma-associated exfoliative dermatitis previously described in rabbits. The liver exhibited an interface hepatitis, comparable to autoimmune hepatitis in man. The occurrence of morphological similarities to exfoliative dermatitis and sebaceous adenitis in rabbits, in association with an autoimmune hepatitis, has not been described before.  相似文献   

Spatiotemporal Distribution of Two Euschistus spp. Stink Bugs (Hemiptera: Pentatomidae) in Southeastern Farmscapes     

Erin E Grabarczyk  Russell F Mizell  III  Jeremy K Greene  Gary A Herzog  P Glynn Tillman  Ted E Cottrell 《Journal of insect science (Online)》2022,22(1)

Stink bugs (Hemiptera: Pentatomidae) are ubiquitous, cryptic, phytophagous pests that are found in many crops. In agroecosystems, individuals disperse from adjacent noncrop hosts and tend to aggregate or cluster within fields. In this study, we characterized the distribution of Euschistus servus (Say) and Euschistus tristigmus (Say) (Hemiptera: Pentatomidae) over 2 yr at three southeastern United States farmscapes. Stink bugs were captured in pheromone-baited traps, and Spatial Analysis by Distance Indices (SADIE) used to identify the location of significant aggregations by habitat type and season. Euschistus servus adults were more likely to be captured in pecan orchards, cotton, other crops, or unmanaged habitats than in woodland habitats. Significant aggregations of E. servus were detected in a variety of habitats including pecan, corn, cotton, peanut, and tobacco, as well as fallow and hay fields, pastures, and hedgerows. Fewer adult E. tristigmus were captured than E. servus adults, and E. tristigmus adults were typically trapped and aggregated in woodland habitats. The resulting data provide an important understanding regarding the seasonal movement and relative abundance levels of stink bug populations, which are critical to the development of integrated pest management strategies.  相似文献   

Validating the use of Cs measurements to estimate rates of soil redistribution by wind     

R. Scott Van Pelt  Ted M. Zobeck  Jerry C. Ritchie  Thomas E. Gill 《CATENA》2007,70(3):455-464

Wind erosion has degraded over one-half billion hectares of land worldwide. ¹³⁷Cesium (¹³⁷Cs) has been used as a tracer to study long-term rates of soil redistribution by water and, to a lesser extent, by wind. Early studies assumed that the decline in ¹³⁷Cs activity for a potentially eroded soil relative to that for an uneroded soil was linearly proportional to soil loss. More recently, models have emerged that consider the effects of soil cultivation and the particle surface area-dependent partitioning of ¹³⁷Cs on soils. We investigated the partitioning of ¹³⁷Cs in wind-eroded sediments and with soil surface samples sieved into contiguous ranges of particle sizes. We also compared the ¹³⁷Cs activities and stratification of several adjacent soils with known wind erosion and deposition histories. Finally, we tested ¹³⁷Cs-based soil loss models with measured data from sites with documented histories. ¹³⁷Cs activities and mean particle diameters of aeolian samples agreed well with the ¹³⁷Cs activities and respective mean diameters of the sieved surface soil samples. Good agreement between model estimations and measured data indicated that ¹³⁷Cs models developed to estimate soil redistribution by water were also applicable to soil redistribution by wind provided that the models contained an appropriate particle size correction parameter.  相似文献   

Improving the management of commercial giant mottled eel Anguilla marmorata aquaculture in Taiwan for improved productivity: a bioeconomic analysis     

Cheng-Ting Huang  Jun-Ting Chiou  Hieu Truong Khac  Yao-Jen Hsiao  Shin-Chang Chen 《Fisheries Science》2016,82(1):95-111

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Use of a three-drill-tract technique for arthrodesis of the distal tarsal joints in horses with distal tarsal osteoarthritis: 54 cases (1990-1999)     

Dechant JE  Baxter GM  Southwood LL  Crawford WH  Jackman BR  Stashak TS  Trotter GW  Hendrickson DA 《Journal of the American Veterinary Medical Association》2003,223(12):1800-1805

OBJECTIVE: To assess the long-term clinical outcome of horses with distal tarsal osteoarthritis (OA) in which a 3-drill-tract technique was used to induce arthrodesis of the affected joints, identify any preoperative or operative factors associated with outcome, and describe any complications associated with the technique. DESIGN: Retrospective study. ANIMALS: 54 horses. PROCEDURE: Medical records were reviewed for information on signalment, use, history, physical and lameness examination findings, surgical technique, and postoperative care. Radiographs were examined, and severity of OA was graded. Follow-up information was obtained through telephone interviews with owners at least 13 months after the procedure. RESULTS: 32 (59%) horses had a successful outcome, 6 (11%) improved but were not sound after surgery, and 16 (30%) did not improve following surgery. Outcome was negatively associated with the previous use of intra-articular injections. Few postoperative complications were evident. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that distal tarsal OA in horses can be successfully treated by means of distal tarsal arthrodesis with a 3-drill-tract technique. Horses with advanced distal tarsal OA are likely to have poorer outcomes, and the procedure will likely be of minimal benefit in horses with concomitant causes of hind limb lameness prior to surgery and in horses with preexisting proximal intertarsal joint disease.  相似文献   

Technical variability and required sample size of helminth egg isolation procedures     

Mes TH 《Veterinary parasitology》2003,115(4):311-320

Measurements of parasite load are often very variable. This implies that little confidence can be attached to single measurements of parasite numbers and egg concentrations, and that many measurements are required for the detection of differences between groups of hosts or parasites. For studies that aim to detect these differences, it is important to increase the precision (closeness of repeated measures to each other) of parasite numbers, because it determines the number of samples that is needed to find significant differences among groups. In this study, sample sizes required to detect group differences were estimated using nematode egg counts of faecal samples of dairy cattle. They were found to be much lower for a centrifugation technique than for the widely used McMaster technique in replicate samples, in spite of a generally similar mean FEC. For example, the sample size required to detect FEC differences between groups of 10, 50, and 250 eggs per gram (EPG) were 46, 25, and 27 for the McMaster technique and 8, 5, and 12 for the SSF method, respectively. Interestingly, sample sizes required for faeces with a relatively high egg concentration (approximately 1000 EPG) were also considerably lower than for the McMaster technique in spite of a higher mean EPG of the latter method. This implies that technical variation can be reduced considerably by simple methods of egg isolation. Given that the range of egg concentration is similar for a number of nematodes of livestock and human helminths, a reduction of technical error will aid studies with many group comparisons such as vaccination strategies against parasites with typically low FECs and studies of the genetics of host resistance. It may also lead to improved guidelines for measures related to public health.  相似文献   

In vitro anion transport alterations and apoptosis induced by phenylbutazone in the right dorsal colon of ponies     

Richter RA  Freeman DE  Wallig M  Whittem T  Baker GJ 《American journal of veterinary research》2002,63(7):934-941

OBJECTIVES: To study the functional and structural responses of the right dorsal colon (RDC) of ponies to phenylbutazone (PBZ) in vitro at a concentration that could be achieved in vivo. ANIMALS: 8 adult ponies. PROCEDURE: Short circuit current and conductance were measured in mucosa from the RDC. Tissues incubated with and without HCO3- were exposed to PBZ, bumetanide, or indomethacin. Bidirectional Cl- fluxes were determined. After a baseline flux period, prostaglandin E2 (PGE2) was added to the serosal surfaces and a second flux period followed. Light and transmission electron microscopy were performed. RESULTS: Baseline short circuit current was diminished significantly by PBZ and indomethacin, and increased significantly after addictions of PGE2. After PGE2 was added, Cl- secretion increased significantly in tissues in HCO3- -free solutions and solutions with anti-inflammatory drugs, compared with corresponding baseline measurements and with control tissues exposed to PGE2. Bumetanide did not affect baseline short circuit current and Cl- fluxes. The predominant histologic change was apoptosis of surface epithelial cells treated with PBZ and to a lesser extent in those treated with indomethacin. CONCLUSIONS AND CLINICAL RELEVANCE: Prostaglandin-induced Cl- secretion appeared to involve a transporter that might also secrete HCO3-. Both PBZ and indomethacin altered ion transport in RDC and caused apoptosis; PBZ can damage mucosa through a mechanism that could be important in vivo. The clinically harmful effect of PBZ on equine RDC in vivo could be mediated through its effects on Cl- and HCO3- secretion.  相似文献   

Effect of tumor infiltrating lymphocytes on the expression of MHC molecules in canine transmissible venereal tumor cells     

Hsiao YW  Liao KW  Hung SW  Chu RM 《Veterinary immunology and immunopathology》2002,87(1-2):19-27

Canine transmissible venereal tumor (CTVT) can be allo-transplanted across major histocompatibility complex barriers. The expression of MHC molecules is usually low in the progression (P) stage and then greatly increases during tumor regression (R). We investigated the effects of tumor infiltrating lymphocytes (TIL) on the expression of MHC molecules of CTVT cells. Isolated, viable CTVT cells were inoculated at each of 12 sites (1 x 10(8) CTVT cells per site) on the back of six, mixed-breed dogs. Tumor masses were collected every 2-3 weeks and prepared for histopathologic, immunocytochemistry, flow cytometry and immunoblotting studies. The level of MHC expression on tumor cells from different stages of growth was measured. Initially, expression of MHC I and II molecules in P phase CTVT was low. Twelve weeks post-inoculation (PI), expression increased dramatically and it continued to increase during R phase. Tumor growth slowed after 12 weeks PI and tumors entered R phase around 17 weeks PI. We hypothesize that CTVT evades host immunosurveillance and grows progressively for 12 weeks, when it becomes vulnerable and subject to the host's anti-tumor immune responses. We further demonstrated that R phase, but not P phase, TIL were closely associated with the over-expression of MHC I and II molecules by CTVT cells. The number and proportion of TIL were higher in R phase tumors. Supernatants, from R phase co-cultures (CTVT+TIL) and TIL only, promoted MHC I and II expression on P phase CTVT cells. After culturing alone for 1 month, expression of MHC classes I and II molecules in R phase CTVT cells decreased to the level of P phase CTVT cells. However, the above-mentioned supernatants restored their expression of MHC I and II molecules. In contrast, supernatants from P phase TIL or CTVT cells increased expression slightly or had no effect. Therefore, TIL, not CTVT cells, produce the effective substance (s) to promote the expression of MHC molecules by the tumor cells. Heat treated supernatant was unable to promote the expression of MHC I and II molecules by CTVT cells. In conclusion, TIL isolated from R phase CTVT secreted a heat-sensitive, soluble substance(s) that triggered over-expression of MHC I and II after 12 weeks PI. This caused the tumor to enter R phase and helped stop CTVT growth. Our findings will facilitate the understanding and further investigation of the mechanisms that initiate host immune surveillance against tumors.  相似文献