Roy Mervyn Watts     

PJ Mylrea 《Australian veterinary journal》2001,79(11):778-778

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Haematological and biochemical investigations of diseased koalas (Phascolarctos cinereus)     

PJ CANFIELD  ME O'NEILL†  EF SMITH† 《Australian veterinary journal》1989,66(9):269-272

Haematological and biochemical investigations were performed on 14 koalas with uncomplicated cystitis, 8 with complicated cystitis, 8 with conjunctivitis, 8 with lymphosarcoma, and 14 with miscellaneous diseases. Changes were limited and inconsistent in individual koalas with uncomplicated cystitis and conjunctivitis. In contrast, individual koalas with complicated cystitis were more likely to have anaemia, leukocytosis due to neutrophilia, hypoproteinaemia due to hypoalbuminaemia, and azotaemia due to elevated urea concentration. Although these changes were non-specific they did allow assessment of prognosis for survival and response to treatment. Koalas with lymphosarcoma were invariably anaemic, leukaemic, azotaemic and hypoalbuminaemic. Elevated enzymes (aspartate transaminase [AST]. lactate dehydrogenase [LD] and gamma glutamyl transferase [GGT]) were more common in koalas with lymphosarcoma. Koalas affected by miscellaneous conditions showed variable changes but once again anaemia, leukocytosis, azotaemia, elevated AST and LD, and hypoalbuminaemia were not uncommon. On the basis of these findings a minimal profile is suggested for the investigation of sick koalas and would include haematocrit, total and differential leukocyte counts, urea, total protein and albumin concentrations and AST, GGT and LD activities.  相似文献   

The effect of moxidectin against benzimidazole- and levamisole-resistant nematodes of sheep in Western Australia     

RB BESIER  J. LYON  PJ KIERAN 《Australian veterinary journal》1993,70(11):422-423

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Genotypic diversity of Pasteurella multocida isolates from pigs and poultry in Australia          下载免费PDF全文

C Turni  R Singh  PJ Blackall 《Australian veterinary journal》2018,96(10):390-394

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Effect of a one-off sporidesmin challenge on the milk production of dairy cows     

ZM Matthews  MG Collett  JC Marshall  AC Partridge  PJ Derrick  PJB Edwards 《New Zealand veterinary journal》2018,66(5):261-266

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Arthroscopic Removal of Large Extensor Process Fragments in 18 Friesian Horses: Long‐Term Clinical Outcome and Radiological Follow‐Up of the Distal Interphalangeal Joint          下载免费PDF全文

Ellen Compagnie  Frerik ter Braake  Natascha de Heer  Willem Back 《Veterinary surgery : VS》2016,45(4):536-541

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Profile of Steroid Receptors and Increased Aromatase Immunoexpression in Canine Inflammatory Mammary Cancer as a Potential Therapeutic Target          下载免费PDF全文

PJ De Andrés  S Cáceres  M Clemente  MD Pérez‐Alenza  JC Illera  L Peña 《Reproduction in domestic animals》2016,51(2):269-275

Canine inflammatory mammary cancer (IMC) has been proposed as a model for the study of human inflammatory breast cancer (IBC). The aims of this study were to compare the immunohistochemical expression of aromatase (Arom) and several hormone receptors [estrogen receptor α (ERα), estrogen receptor β (ERβ), progesterone receptor (PR) and androgen receptor (AR)], in 21 IMC cases vs 19 non‐IMC; and to study the possible effect of letrozole on canine IMC and human inflammatory breast cancer (IBC) in vitro using IPC‐366 and SUM‐149 cell lines. Significant elevations of the means of Arom Total Score (TS), ERβ TS and PR TS were found in the IMC group (p = 0.025, p = 0.038 and p = 0.037, respectively). Secondary IMC tumours expressed higher levels of Arom than primary IMC (p = 0.029). Non‐IMC PR‐ tumours contained higher levels of Arom than non‐IMC PR+ tumours (p = 0.007). After the addition of letrozole, the number of IMC and IBC cells dropped drastically. The overexpression of Arom found and the results obtained in vitro further support canine IMC as a model for the study of IBC and future approaches to the treatment of dogs with mammary cancer, and especially IMC, using Arom inhibitors.  相似文献   

The effect of induced forelimb lameness on thoracolumbar kinematics during treadmill locomotion     

Gómez Alvarez CB  Wennerstrand J  Bobbert MF  Lamers L  Johnston C  Back W  van Weeren PR 《Equine veterinary journal》2007,39(3):197-201

REASONS FOR PERFORMING STUDY: Lameness has often been suggested to result in altered movement of the back, but there are no detailed studies describing such a relationship in quantitative terms. OBJECTIVES: To quantify the effect of induced subtle forelimb lameness on thoracolumbar kinematics in the horse. METHODS: Kinematics of 6 riding horses was measured at walk and at trot on a treadmill before and after the induction of reversible forelimb lameness grade 2 (AAEP scale 1-5). Ground reaction forces (GRF) for individual limbs were calculated from kinematics. RESULTS: The horses significantly unloaded the painful limb by 11.5% at trot, while unloading at walk was not significant. The overall flexion-extension range of back motion decreased on average by 0.2 degrees at walk and increased by 3.3 degrees at trot (P<0.05). Changes in angular motion patterns of vertebral joints were noted only at trot, with an increase in flexion of 0.9 degrees at T10 (i.e. angle between T6, T10 and T13) during the stance phase of the sound diagonal and an increase in extension of the thoracolumbar area during stance of the lame diagonal (0.7degrees at T13, 0.8 degres at T17, 0.5 degres at L1, 0.4 degrees at L3 and 0.3 degrees at L5) (P<0.05). Lameness further caused a lateral bending of the cranial thoracic vertebral column towards the lame side (1.3 degrees at T10 and 0.9 degrees at T13) (P<0.05) during stance of the lame diagonal. CONCLUSIONS: Both range of motion and vertebral angular motion patterns are affected by subtle forelimb lameness. At walk, the effect is minimal, at trot the horses increased the vertebral range of motion and changed the pattern of thoracolumbar motion in the sagittal and horizontal planes, presumably in an attempt to move the centre of gravity away from the lame side and reduce the force on the affected limb. POTENTIAL RELEVANCE: Subtle forelimb lameness affects thoracolumbar kinematics. Future studies should aim at elucidating whether the altered movement patterns lead to back and/or neck dysfunction in the case of chronic lameness.  相似文献   

Population dynamics of the potato cyst nematode,Globodera pallida,in relation to temperature,potato cultivar and nematicide application     

A. M. Kaczmarek  M. Back  V. C. Blok 《Plant pathology》2019,68(5):962-976

The impact of increasing temperatures on the population dynamics of the soil-dwelling nematode Globodera pallida, a persistent and economically important pest of potatoes, was investigated. The reproductive factor (final population⁄initial population) and length of life cycle were found to be temperature sensitive. Pot experiments performed over 4 months allowed comparison of the effect on development of G. pallida of two temperature regimes: an average temperature comparable to current field conditions (14.3 °C) and an average temperature above current field conditions (17.3 °C). A larger second generation of juveniles was observed at 17.3 °C compared to 14.3 °C. Multiplication of G. pallida at field sites in Shropshire and East Lothian (average soil temperatures of 15.5 and 14.1 °C, respectively, during potato cropping) was also examined. A quantitative PCR assay and visual examination of roots were used to monitor the dynamics of the G. pallida populations in both field sites at 4-weekly intervals. Four cultivars, Desirée, Cara, Maris Piper and Estima, were grown with and without nematicide treatments. Nematicide treatments suppressed population increases at both sites. Females were observed on the roots of cvs Cara and Desirée at the end of the growing season in Shropshire, but not at East Lothian, and are likely to represent a second generation.  相似文献   

辣椒倍半萜植保素代谢的分子生态学研究   总被引：1，自引：0，他引：1  

何水林林文雄  陈如凯白镜焕申东贤  金吉雄 《农业生物技术学报》1999,7(4):1

为建立克隆辣椒倍半萜环化酶基因的cDNA文库,我们尝试了用紫外线（UV）处理离体辣椒叶片,考察UV对辣椒倍半萜环化酶活性的影响,结果表明UV能诱导辣椒叶片表达倍半萜环化酶活性;不同抗性水平的辣椒品种倍半萜环化酶活性对紫外线的反应有差异,紫外线处理后,抗病品种cm334在24 h 出现酶活性高峰,而感病品种subiche在36～42 h出现酶活性高峰; 在紫外线处理后0～24 h cm334的酶活性高于subiche。UV对辣椒倍半萜环化酶活性的诱导作用与UV的作用方式、剂量及辣椒植株的生育期有关, 紫外线交联处理45 s诱导10叶期的倍半萜环化酶活性最高;5支15 W紫外灯相距20 cm照射15 min低于1支相同的紫外灯处理;在相同的UV作用下,开花前辣椒叶片倍半萜环化酶活性显著高于开花以后的辣椒叶片。另一方面,紫外线处理是辣椒叶片中的鲨烯合成酶活性受到一定程度的拟制。  相似文献