Squamous gastric ulceration complicated by gastric stenosis in a foal     

P. Witt  L. de Kroon  N. Ankringa  M. Delany  L. W. L. van Bruggen  R. van den Boom  M. M. Sloet van Oldruitenborgh-Oosterbaan  E. W. Siegers 《Equine Veterinary Education》2022,34(9):e369-e374

A 2-month-old Warmblood colt presented with recurrent colic and regurgitation. Gastroscopy, performed on several occasions, and barium-contrast radiography revealed severe squamous gastric ulceration and stenosis at the level of the margo plicatus. Treatment with omeprazole reduced the extent and severity of the gastric ulcers but did not affect the stenosis. The foal was euthanised because of a poor prognosis, and post-mortem examination confirmed the clinical diagnosis. Severe squamous gastric ulceration, granulation tissue formation and cicatrisation of deep gastric lesions were considered to have caused the stenosis. Gastroduodenal outflow obstruction is a recognised disorder in foals, but stenosis at the level of the margo plicatus has not been reported in foals or adult horses. To the authors' knowledge, this is the first case of severe squamous gastric ulceration, complicated by stenosis at the level of the margo plicatus, in a foal. Although rare, gastric stenosis should be considered in foals suffering recurrent colic and regurgitation.  相似文献   

CHANGES IN ULTRASONOGRAPHIC APPEARANCE OF ADRENAL GLANDS IN DOGS WITH PITUITARY-DEPENDENT HYPERADRENOCORTICISM TREATED WITH TRILOSTANE     

Panagiotis  Mantis  DVM  Christopher R.  Lamb  MA  VetMB  Angela L.  Witt  DVM  Reto  Neiger  Dr Med Vet  PhD 《Veterinary radiology & ultrasound》2003,44(6):682-685

Trilostane, a 3beta-hydroxysteroid dehydrogenase inhibitor, has been used successfully over the last few years for the treatment of canine pituitary-dependent hyperadrenocorticism. In a prospective study of 19 dogs with pituitary-dependent hyperadrenocorticism, the adrenal glands were measured before and at least 6 months after initiation of trilostane therapy. Right adrenal gland length and caudal pole thickness and left adrenal gland caudal pole thickness increased significantly (p < or = 0.05); there was no significant change in left adrenal gland length. Enlargement of adrenal glands during trilostane therapy may occur as a result of suppression of the negative feedback mechanism affecting cortisol production.  相似文献   

Comment on "Molecular phylogenies link rates of evolution and speciation" (I)     

Witt CC  Brumfield RT 《Science (New York, N.Y.)》2004,303(5655):173; author reply 173

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Pyrrolizidine alkaloid-induced liver disease in horses: an early diagnosis     

V E Mendel  M R Witt  B S Gitchell  D N Gribble  Q R Rogers  H J Segall  H D Knight 《American journal of veterinary research》1988,49(4):572-578

Nine adult horses were fed alfalfa hay cubes containing approximately 10% Senecio vulgaris until all horses had consumed approximately the same amount of toxic components of S vulgaris, pyrrolizidine alkaloids (PA). The amount of PA consumed was determined by the amount that induced clinical signs of PA toxicosis in 3 horses. The 6 other horses were given similar amounts per kilogram of body weight. An initial decrease of feed intake was observed when horses' diets were changed from alfalfa cubes to alfalfa/Senecio cubes, and feed intake was decreased further over 89 to 98 days. From 50 to 159 days, body weight decreased in all horses. Liver disease was induced in all 9 horses after they ate an average of 233 +/- 9.2 mg of PA/kg of body weight. Eight horses died or were euthanatized. Treatment with branched chain amino acids had no effect on mortality, but appeared to reduce neurologic problems. Clinical signs of PA-induced liver disease included ataxia, head pressing, and decreased feed intake. Other clinical signs of toxicosis were observed individual horses, but did not develop in most horses. Megalocytic hepatopathy developed. Liver abnormalities proceeded as PA was consumed and were severe in 8 of 9 horses before clinical signs of toxicosis appeared. Sulfobromophthalein sodium clearance did not decrease until PA-induced liver disease was advanced. Bile acid (BA) concentrations increased to greater than or equal to 50 mumol/L, in the 8 horses that died. One horse had hepatopathy and increased BA concentration, but survived. In this horse, BA concentration peaked at 33 mumol/L and then decreased.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

The effect of erythritol on the growth of S19 and other attenuated strains of Brucella abortus   总被引：2，自引：0，他引：2  

J Keppie  K Witt  H Smith 《Research in veterinary science》1967,8(3):294-296

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Adrenocorticotropic hormone levels in dogs with pituitary-dependent hyperadrenocorticism following trilostane therapy     

Witt AL  Neiger R 《The Veterinary record》2004,154(13):399-400

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Laparoscopic-assisted cystotomy for urolith removal in geldings     

Röcken M  Stehle C  Mosel G  Rass J  Litzke LF 《Veterinary surgery : VS》2006,35(4):394-397

OBJECTIVE: To describe a technique for laparoscopic-assisted removal of cystic calculi in geldings and report outcome. STUDY DESIGN: Clinical report. ANIMALS: Four geldings with cystic calculi. METHODS: Laparoscopic-assisted cystotomy and urolith retrieval was performed in 4 anesthetized geldings positioned in dorsal recumbency. With a laparoscope portal located at the umbilicus, the abdomen was insufflated and then the surgical table was tilted (30 degrees head-down position) before an instrumental portal was created parallel and 2-3 cm medial to the left external inguinal ring. Laparoscopic grasping forceps were inserted to grasp the cranial aspect of the bladder and elevate it to the ventral abdominal wall. With the instrumental portal as mid-point, the parainguinal skin incision was longitudinally extended cranial and caudal (approximately 8-10 cm) to accommodate the size of the urolith. The apex of the bladder was exteriorized and sharply incised, the urolith extracted, and after cystotomy closure, the bladder was repositioned. The mini-laparotomy and trocar incisions were closed in layers. RESULTS: There were no intra- or post-operative complications. All horses had minor incisional swelling for 3-4 days. No signs of abdominal or incisional pain were observed. Hematuria and slight stranguria occurred until the 3rd or 4th day. Surgical time (skin incision to skin closure) was 35-40 minutes. On long-term follow-up (up to 12 months) no recurrence of clinical signs associated with cystic calculi occurred. CONCLUSION: Uroliths (6-8 cm diameter) can be removed by laparoscopic-assisted cystotomy in geldings. CLINICAL RELEVANCE: Laparoscopic-assisted cystotomy combines the advantages of the parainguinal laparocystotomy with laparoscopic technique for removal of cystic calculi while avoiding their disadvantages.  相似文献   

Exploratory trials on reinforcement of veld with legumes in the south‐eastern transvaal highveld     

D L Barnes  N F G Rethman  C C De Witt  G D Kotze 《African Journal of Range and Forage Science》2013,30(3):90-95

Abstract

The feasibility and potential of reinforcing veld with legumes in the south‐eastern Transvaal highveld was assessed in a number of trials during the period 1974–84. Experience was gained with regard to methods of establishment, adaptation of legumes to the local environment, responses to fertilization, especially with lime and superphosphate, and the reaction of legumes to fire and grazing. In all, 17 legumes were involved, including the genera Coronilla, Desmodium, Glycine, Lespedeza, Lotus, Macroptilium, Medicago, Neoto‐nonia, Trifolium and Vigna. Only Coronilla varia (crownvetch) showed a satisfactory degree of persistence. However, crownvetch is slow to establish, is intolerant of waterlogging and has a relatively high requirement for lime and phosphate. Considering these features, and the probability of undesirable changes in grass species composition in reinforced veld, it is recommended that intensification be achieved through development of improved pastures for use in conjunction with veld, rather than by means of veld reinforcement.  相似文献   

Soil microbial biomass and nitrogen supply in an irrigated lowland rice soil as affected by crop rotation and residue management   总被引：5，自引：0，他引：5  

C. Witt  Kenneth G. Cassman  Johannes C. G. Ottow  Ulrich Biker 《Biology and Fertility of Soils》1998,28(1):71-80

 Processes that govern the soil nitrogen (N) supply in irrigated lowland rice systems are poorly understood. The objectives of this paper were to investigate the effects of crop rotation and management on soil N dynamics, microbial biomass C (C_BIO) and microbial biomass N (N_BIO) in relation to rice N uptake and yield. A maize-rice (M-R) rotation was compared with a rice-rice (R-R) double-cropping system over a 2-year period with four cropping seasons. In the M-R system, maize (Zea mays L.) was grown in aerated soil during the dry season (DS) followed by rice (Oryza sativa L.) grown in flooded soil during the wet season (WS). In the R-R system, rice was grown in flooded soil in both the DS and WS. Three fertilizer N rates (0, 50 or 100 kg urea-N ha^–1 in WS) were assigned to subplots within the cropping system main plots. Early versus late crop residue incorporation following DS maize or rice were established as additional treatments in sub-subplots in the second year. In the R-R system, the time of residue incorporation had a large effect on NO₃ ^–-N accumulation during the fallow period and also on extractable NH₄ ⁺-N, rice N uptake and yield in the subsequent cropping period. In contrast, time of residue incorporation had little influence on extractable N in both the fallow and rice-cropping periods of the M-R system, and no detectable effects on rice N uptake or yield. In both cropping systems, C_BIO and N_BIO were not sensitive to residue incorporation despite differences of 2- to 3-fold increase in the amount of incorporated residue C and N, and were relatively insensitive to N fertilizer application. Extractable organic N was consistently greater after mid-tillering in M-R compared to the R-R system across N rate and residue incorporation treatments, and much of this organic N was α-amino N. We conclude that N mineralization-immobilization dynamics in lowland rice systems are sensitive to soil aeration as influenced by residue management in the fallow period and crop rotation, and that these factors have agronomically significant effects on rice N uptake and yield. Microbial biomass measurements, however, were a poor indicator of these dynamics. Received: 31 October 1997  相似文献   

Using systematic conservation planning to establish management priorities for freshwater salmon conservation,Matanuska‐Susitna Basin,AK, USA          下载免费PDF全文

Andrew Witt  Edd Hammill 《水产资源保护:海洋与淡水生态系统》2018,28(4):994-1003