Pathology of genetically engineered mice, Ward JM, Maranpot JR, Sundberg JP, Frederickson RM     

DA Pass 《Australian veterinary journal》2001,79(3):198-198

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8 MEASUREMENT OF ARTICULAR CARTILAGE STIFFNESS IN THE FEMOROPATELLAR, TARSOCRURAL AND METATARSOPHALANGEAL JOINTS OF HORSES AS A PREDICTOR OF CARTILAGE PATHOLOGY.     

E  Garcia-Seco  DA Wilson  K Kuroki  J Cook  J Kreeger  KG Keegan 《Veterinary surgery : VS》2003,32(6):600-600

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Flow cytometric analysis of T cell response in mice infected with Cowdria ruminantium.     

J L Du Plessis  C Gray  M F Van Strijp 《The Onderstepoort journal of veterinary research》1992,59(4):337-338

A 3-fold increase in the numbers of Lyt-2+ T cells in the circulating blood of mice infected and re-infected with the Welgevonden stock of Cowdria ruminantium, as determined by flow cytometry, is supportive evidence that immunity in heartwater is cell-mediated. The rise in Lyt-2+ cells only after re-infection of the mice is further evidence that the development of immunity in heartwater is dependent on the unhindered and adequate replication of C. ruminantium.  相似文献   

Borax toxicity     

Brockman RP  Audette RJ  Gray M 《The Canadian veterinary journal. La revue veterinaire canadienne》1985,26(4):147

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The influence of cell type on the production of filaments by herpes simplex virus type 2.     

I W Smith  J F Peutherer  O G Gray 《Comparative immunology, microbiology and infectious diseases》1979,2(2-3):191-199

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An improved ferritin assay for canine sera     

Andrews GA  Smith JE  Gray M  Chavey PS  Weeks BR 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1992,21(2):57-60

An improved serum ferritin assay for canine serum has been developed. It uses two monoclonal antibodies in a sandwich arrangement. Serum ferritin can be determined on undiluted canine sera with this assay. The recovery of ferritin added to canine serum ranged from 98 to 106%, the within-assay coefficient of variability was 3.3 to 4.5%, and the assay-to-assay variability was 9.8 to 10.2%. Serum ferritin from 61 apparently healthy dogs had a geometric mean of 252 ng/ml, with a range of 80 ng/ml to 800 ng/ml.  相似文献   

The relationship between the pharmacokinetics of intravenous cismethrin and bioresmethrin and their mammalian toxicity     

A.J. Gray  T.A. Connors  H. Hoellinger 《Pesticide biochemistry and physiology》1980,13(3):281-293

The distribution and excretion of [¹⁴C]alcohol-labeled cismethrin and bioresmethrin was determined after intravenous administration to rats. Initially the label distribution of both isomers was similar, but differences occurred at later times mainly due to the retention of 5-benzyl-3-furylcarboxylic acid, a metabolite of bioresmethrin, in high concentration in the blood. Retention of this metabolite accounted for the slower excretion of bioresmethrin label compared to cismethrin. After administration of either isomer, parent pyrethroid was rapidly cleared from the blood and liver, and both isomers rapidly entered the central nervous system reaching peak concentrations within 2–5 min. Brain cismethrin concentrations exceeding 3.5 nmol/g were associated only with animals showing tremors. These levels of cismethrin are maintained for up to 30 min but bioresmethrin was depleted more rapidly possibly due to brain metabolism. It is concluded that the low toxicity of bioresmethrin is possibly due to the inability of this isomer to interact with the site of action in the central nervous system and not, as previously suggested, primarily because of more rapid metabolism in the liver.  相似文献   

绵羊卵泡发育过程中关键信号通路研究进展     

陈欣  达赖  付绍印  祁云霞  王标  何小龙  马跃军  方勤圆  张林  贾明蕊  董鹏  刘永斌 《中国畜牧兽医》2021,48(3):963-974

卵泡从原始卵泡发育为成熟卵泡，直至排卵、黄体发育等过程都受到精密的调控，产生大量的优势卵泡是绵羊产多羔及实现快速扩繁的关键因素。研究发现，相关信号通路和转录因子通过影响绵羊卵泡中卵母细胞、颗粒细胞的生长，进而调控卵泡的发育成熟，对这些信号通路进行深入了解，有助于探索卵泡发育的调控机制，早日实现绵羊高效繁育。Notch是卵泡发育过程中发挥重要作用的高度保守信号通路，PI3K/AKT/mTOR信号通路各成员都是广泛存在于细胞内的信号转导分子，在卵泡发育早期发挥了主要作用，还有间隙连接（gap junction，GJ）和跨带突触（transzonal projections，TZPs）等物理连接方式，在细胞间的交流通讯起到重要作用。作者详细介绍了Notch信号通路、PI3K/AKT/mTOR信号通路、间隙连接及跨带突触的结构功能在绵羊卵泡发育中的调控作用，为进一步探明绵羊卵泡发育的调控机制提供参考。  相似文献   

以全产业链思维优化甘肃省“粮改饲”生产力布局     

笪晓军  王兴琪  刘永康  马璐  王凤萍 《中国饲料》2021,1(6):143-146

用全产业链思维优化“粮改饲”生产力布局具有重要的现实意义和理论价值。本文以甘肃省为例,总结甘肃省“粮改饲”工作已取得的工作成效和不足,论述了“粮改饲”构建全产业链的必要性,初步探讨了甘肃省“粮改饲”全产业链模式和布局优化,并提出完善相关支持政策、培育壮大龙头企业、高度重视品牌建设和创新科技带动引领4条对策建议。 [关键词]全产业链|粮改饲|生产力布局|甘肃省  相似文献   

Approaches to pathogen-mediated resistance breeding against plum pox potyvirus in stone-fruit trees1     

A. DA CMARA MACHADO  E. KNAPP  H. PÜHRINGER  G. SEIFERT  V. HANZER  H. WEISS  H. KATINGER  M. LAIMER DA CMARA MACHADO 《EPPO Bulletin》1994,24(3):697-704

In a programme for developing systems which allow the transfer of foreign genes into apricot cultivars, we have tested cotyledons of immature embryos, somatic embryos and leaf discs. Apricot plants have been transformed, and then regenerated, with Agrobacterium tumefaciens strain LBA 4404 containing various binary plasmids: pBinGUSint, carrying the marker gene β-glucuronidase (GUS), and pBinPPVm, carrying the coat-protein gene of plum pox potyvirus (PPV). The marker gene GUS was used for visual evaluation of the efficiency of the transformation system. The coat-protein gene was used in the hope of introducing coat protein-mediated resistance to one of the most important stone-fruit pathogens in Europe and the Mediterranean area.  相似文献