Scientific decision-making in school     

Moorman T 《Science (New York, N.Y.)》1989,244(4900):11-12

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The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse          下载免费PDF全文

Aimée C. Colbath  Luke A. Wittenburg  Jenifer R. Gold  C. Wayne McIlwraith  Valerie J. Moorman 《Veterinary surgery : VS》2016,45(6):798-803

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Colloid oncotic pressure and total protein changes in horses during anesthesia fluid therapy     

P Boscan  Z Watson  TB Farver  EP Steffey 《Veterinary anaesthesia and analgesia》2005,32(4):16-16

It is unknown whether overlapping or sequential use of nonsteroidal anti‐inflammatory (NSAIDs) results in an increased risk for gastrointestinal (GI) ulceration. The purpose of this pilot study was to evaluate the GI effects of various combinations of an injectable NSAID followed by an oral NSAID, a scenario often employed clinically for management of the pre‐ and post‐operative canine patient. Six healthy Walker hounds received four treatment regimens in a randomized, cross‐over design with a 2 week washout period between each treatment week: carprofen (4 mg kg^–1, SQ) followed by placebo (PO, q24 × 4 days); placebo (SQ) followed by deracoxib (3–4 mg kg^–1, PO, q24 × 4 days); carprofen (4 mg kg^–1, SQ) followed by carprofen (4 mg kg^–1, PO, q24 × 4 days); carprofen (4 mg kg^–1, SQ) followed by deracoxib (3–4 mg kg^–1, PO, q24 ×4 days). Weekly bloodwork (CBC, biochemistry panel, fecal evaluation, fecal occult blood) and daily clinical scoring (TPR, vomiting, diarrhea, appetite) were obtained. GI endoscopy was performed on days –2, 1, 2, 5, and 11 days post treatment of each treatment period and lesions scored using a previously reported 6‐point scale. Data was analyzed using a mixed anova for repeated measures. There were no significant differences in clinical or clinicopathologic data between groups. Within the carprofen‐carprofen and carprofen‐deracoxib groups, lesions worsened by Day 5 (1 day after last oral dose) for the fundic and antral regions (p < 0.05). Fundic, antral and lesser curvature lesions improved by Day 5 in the carprofen‐placebo group and lesser curvature lesions improved in the placebo‐deracoxib group (p < 0.05). No significant within‐group differences were noted for the esophagus, cardia or duodenum. The small number of dogs precludes general conclusions about the safety of sequential NSAID use, but these results suggest that a larger scale study is warranted.  相似文献   

Toxoplasma gondii in an African crested porcupine (Hystrix cristata).     

Tara M Harrison  Jamee Black Moorman  Steven R Bolin  Nicole L Grosjean  Ailam Lim  Scott D Fitzgerald 《Journal of veterinary diagnostic investigation》2007,19(2):191-194

An adult female crested porcupine (Hystrix cristata) was evaluated for acute onset of neurologic signs including head tilt, circling, and ataxia. She was found dead in her holding area 2 days after initially exhibiting clinical signs. Necropsy was unremarkable. Histopathology of brain tissue revealed the presence of protozoal cysts associated with inflammation as the underlying cause of clinical signs and death. Immunohistochemical staining of brain tissue for Toxoplasma gondii was strongly positive. PCR on fresh brain confirmed T. gondii as the causative organism. An adult male in the same enclosure has demonstrated similar neurologic signs over the past 3 years and has failed to respond to various medical treatments. Clinical disease associated with T. gondii has not been previously reported in this porcupine species or any other Old World porcupines, although there are several reports of clinical toxoplasmosis involving New World porcupine species.  相似文献   

Assisted Reproduction in Female Rhinoceros and Elephants – Current Status and Future Perspective     

R Hermes  F Göritz  WJ Streich  TB Hildebrandt 《Reproduction in domestic animals》2007,42(S2):33-44

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Angular orientations derived from a portable media device to assess postural stability during quiet standing in the horse     

V. J. Moorman  M. R. King 《Equine Veterinary Education》2022,34(5):e198-e202

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Degradation and binding of atrazine in surface and subsurface soils   总被引：1，自引：0，他引：1  

Blume E  Bischoff M  Moorman TB  Turco RF 《Journal of agricultural and food chemistry》2004,52(24):7382-7388

Understanding the dissipation rates of chemicals in unsaturated and saturated zones of subsurface soils will help determine if reductions of concentrations to acceptable levels will occur. Chemical properties and microbial biomass and activity were determined for the surface (0-15 cm), lower root (50-105 cm), and vadose (175-220 cm) zones in a Huntington silty clay loam (Fluventic Hapludoll) collected from an agricultural field near Piketon, OH. The rates of sorption, mineralization, and transformation (formation of bound residues and metabolites) of atrazine were determined. Microbial activity was estimated from the mineralization of (14)C-benzoate. We observed decreased levels of nutrients (total organic carbon, N, and P) and microbial biomass with depth, while activity as measured with benzoate metabolism was higher in the vadose zone than in either the surface or the root zones. Sorption coefficients (K(f)) declined from 8.17 in the surface to 3.31 in the vadose zone. Sorption was positively correlated with organic C content. Rates of atrazine mineralization and bound residues formation were, respectively, 12-2.3-fold lower in the vadose than in the surface soil. Estimated half-lives of atrazine ranged from 77 to 101 days in the surface soil, but increased to over 900 days in the subsurface soils. The decreased dissipation of atrazine with increasing depth in the profile is the result of decreased microbial activity toward atrazine, measured either as total biomass or as populations of atrazine-degrading microorganisms. The combination of reduced dissipation and low sorption indicates that there is potential for atrazine movement in the subsurface soils.  相似文献   

Multilineage potential of adult human mesenchymal stem cells   总被引：7，自引：0，他引：7  

Pittenger MF  Mackay AM  Beck SC  Jaiswal RK  Douglas R  Mosca JD  Moorman MA  Simonetti DW  Craig S  Marshak DR 《Science (New York, N.Y.)》1999,284(5411):143-147

Human mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartilage, fat, tendon, muscle, and marrow stroma. Cells that have the characteristics of human mesenchymal stem cells were isolated from marrow aspirates of volunteer donors. These cells displayed a stable phenotype and remained as a monolayer in vitro. These adult stem cells could be induced to differentiate exclusively into the adipocytic, chondrocytic, or osteocytic lineages. Individual stem cells were identified that, when expanded to colonies, retained their multilineage potential.  相似文献   

Micromorphology and surface characteristics of lunar dust and breccia     

Cloud P  Margolis SV  Moorman M  Barker JM  Licari GR  Krinsley D  Barnes VE 《Science (New York, N.Y.)》1970,167(3918):776-778

Although nothing of direct biologic interest was observed in the sample studied, small shaped glass particles and glazed pits resemble objects which elsewhere have been described as fossils. These features, although nonbiological, do bear on processes of lunar weathering and outgassing. The glazed pits are impact features. Fusion of their surfaces released gases. Electron microscopy of the glasses, pits, and angular microfractured mineral grains indicates a prevalence of destructive weathering processes-thermal expansion and contraction, abrasion by by-passing particles, and, of course, impact. ous at room temperature.  相似文献   

Science and government. An international framework to promote access to data     

Arzberger P  Schroeder P  Beaulieu A  Bowker G  Casey K  Laaksonen L  Moorman D  Uhlir P  Wouters P 《Science (New York, N.Y.)》2004,303(5665):1777-1778

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