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Two isochinoline alkaloids, glaucine and oxoglaucine were investigated for their suggested anti-inflammatory influence concerning nitric oxide and cytokine production. Mouse peritoneal macrophages were stimulated with different Toll-like receptor (TLR) ligands such as LPS for TLR4, zymosan for TLR2 and CpG for TLR9. The alkaloids inhibited TNF-α and IL-6 production induced by these ligands. In regard to IL-12 suppressive effect was registered in the case of CpG stimulation. Glaucine succeeded to enhance LPS and zymosan-induced IL-10 production. The reduction of pro-inflammatory cytokines and increase of anti-inflammatory IL-10 are indicative for their use in different acute and chronic inflammatory diseases. 相似文献
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Petya Koeva Christova Aneta B. Lyubenova Kaloyan V. Kostov Slavtcho B. Slavov 《Forest Pathology》2019,49(3)
Two Phytophthora pseudosyringae isolates were recovered from aquatic ecosystems in Bulgaria during a two‐year investigation of Phytophthora distribution in water sources in the country. Isolate RVit2016/6d was derived from Boyana Lake at the Vitosha Mountain, whereas isolate RTr2016/32d was obtained from Erma River at the Ruy Mountain. Both isolates belong to P. pseudosyringae species according to their morphological and physiological characteristics, as well as to the DNA sequence analysis of the internal transcribed spacer (ITS) region. The pathogenicity of the isolates to wild cranberry plants (Vaccinium vitis‐idea) was studied by detached leaves experiments and in planta. Both P. pseudosyringae isolates were able to cause leaf necrosis and death of plants within 3 months. The ability of the pathogens to infect cranberry leaves at different temperatures was also investigated. The significance of P. pseudosyringae species and its potential threat for forest ecosystems is discussed. To our knowledge, this is the first report of P. pseudosyringae isolation in Bulgaria. 相似文献
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Christova Petya K. Dincheva Ivaiyla N. Slavov Slavtcho B. Dobreva Ana M. Yordanova Zhenia P. Dimkova Stela D. Zaprianova Nadejda G. Atanassova Bistra Y. Sobiczewski Piotr Iakimova Elena T. 《植物病害和植物保护杂志》2021,128(6):1531-1545
Journal of Plant Diseases and Protection - The growth response of three phytopathogens to inhibitory activity of essential oils (EOs), derived from three monarda (Monarda didyma L.) genotypes, was... 相似文献
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Ganka Chaneva Petya Parvanova Nikolina Tzvetkova Alexandra Uzunova 《Water, air, and soil pollution》2010,208(1-4):287-293
The effects of cadmium (Cd) and/or paraquat (PQ) toxicity on photosynthesis in maize leaves were examined by measurement of gas exchange and chlorophyll content in hydroponically cultured plants. It was found that growth rate was distinctly influenced only by 100 µM Cd treatment. Chlorophyll a and chlorophyll b decreased along with the increase of Cd concentration, while PQ spraying, alone and combined with Cd, increased chlorophyll a content on the third and seventh experimental days. Generally, carotenoid content increased in response to Cd and PQ and reached the highest levels at 100 µM Cd. Rate of photosynthesis in maize decreased after Cd treatment. CO2 assimilation was approximately 60% reduced at 50 µM Cd and 70% reduced in the presence of 100 µM Cd. PQ toxicity was partly overcome after the third day of exposure. Transpiration and stomatal conductance in maize leaves decreased on the third day along with Cd concentration and PQ spraying, except for the 25-µM Cd-treated plants. On the tenth day, the 25-µM Cd-treated plants and those from PQ-treated variants showed an increase of transpiration and stomatal conductance. Maize exhibited an ability to accumulate Cd in high quantities, especially in the roots—over 4,500 mg Cd/kg dry weight. 相似文献
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Journal of Plant Diseases and Protection - Co-existence of four Phytophthora species in a small river in Bulgaria was established—P. plurivora, P. gonapodyides, P. chlamydospora and P.... 相似文献
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