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1.
Glickman LT Glickman NW Schellenberg DB Raghavan M Lee TL 《Journal of the American Veterinary Medical Association》2000,216(1):40-45
OBJECTIVE: To compare incidence of and breed-related risk factors for gastric dilatation-volvulus (GDV) among 11 dog breeds (Akita, Bloodhound, Collie, Great Dane, Irish Setter, Irish Wolfhound, Newfoundland, Rottweiler, Saint Bernard, Standard Poodle, and Weimaraner). DESIGN: Prospective cohort study. ANIMALS: 1,914 dogs. PROCEDURE: Owners of dogs that did not have a history of GDV were recruited at dog shows, and the dog's length and height and depth and width of the thorax and abdomen were measured. Information concerning the dogs' medical history, genetic background, personality, and diet was obtained from owners, and owners were contacted by mail and telephone at approximately 1-year intervals to determine whether dogs had developed GDV or died. Incidence of GDV based on the number of dog-years at risk was calculated for each breed, and breed-related risk factors were identified. RESULTS AND CLINICAL RELEVANCE: Incidence of GDV for the 7 large (23 to 45 kg [50 to 99 lb]) and 4 giant (> 45 kg [> 99 lb]) breeds was 23 and 26 cases/1,000 dog-years at risk, respectively. Of the 105 dogs that developed GDV, 30 (28.6%) died. Incidence of GDV increased with increasing age. Cumulative incidence of GDV was 5.7% for all breeds. The only breed-specific characteristic significantly associated with a decreased incidence of GDV was an owner-perceived personality trait of happiness. 相似文献
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Richter Jana Baltruschat Helmut Kabrodt Kathrin Schellenberg Ingo 《植物病害和植物保护杂志》2011,118(3-4):109-118
Journal of Plant Diseases and Protection - The importance of herbal plants is evident in the prevalent use as flavoring ingredients in food. However, meeting the growing demand for organic grown... 相似文献
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Wang Hai Ta Na Jin Ke Ji Baoming Schellenberg Michael P. Wei Zhijun Wang Zhen 《Journal of Soils and Sediments》2020,20(3):1344-1356
Journal of Soils and Sediments - Fungi play an essential role in regulating the functioning of terrestrial ecosystems and are sensitive to climate change factors. Climate change incidents, such as... 相似文献
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Validation of an enzyme‐linked immunosorbent assay (ELISA) for the measurement of canine S100A12
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Schellenberg S Mettler M Gentilini F Portmann R Glaus TM Reusch CE 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2008,22(2):273-281
BACKGROUND: Hypertension and proteinuria are commonly recognized in dogs with spontaneous hypercortisolism. There is, however, little information regarding the effect of exogenous glucocorticoids on blood pressure (BP) and proteinuria and whether these changes are reversible. HYPOTHESIS: Hydrocortisone administration increases systemic BP and urinary protein excretion, and these effects are reversible after hydrocortisone withdrawal. Animals: Six control dogs and 6 dogs treated with hydrocortisone. METHODS: BP, urine protein : creatinine ratio (UPC), microalbuminuria (MALB), urine albumin : creatinine ratio (UAC), and urine gel electrophoresis were evaluated before, during, and after administration of hydrocortisone (8 mg/kg PO q12h for 12 weeks) or placebo. RESULTS: BP and UPC increased substantially during hydrocortisone administration from 123 mmHg (range 114-136 mmHg) and 0.17 (0.15-0.28) to a maximum of 143 mmHg (128-148 mmHg) and 0.38 (0.18-1.78), respectively, on day 28. MALB developed in 4 dogs and UAC significantly increased in all dogs during hydrocortisone administration with the maximum on day 84. Both increases in BP and proteinuria were reversible and completely resolved within 1 month after stopping hydrocortisone administration. SDS-AGE revealed the proteinuria to be primarily albuminuria with a pronounced increase during hydrocortisone treatment. Furthermore, a protein of 25-30 kDa was found in male dogs, identified by mass spectrometry to be arginine esterase, the major secretory prostatic protein. CONCLUSIONS AND CLINICAL IMPORTANCE: Long-term hydrocortisone treatment results in significant but only mild increases in systemic BP and urinary protein excretion, which are both reversible within 1 month after discontinuation of hydrocortisone. 相似文献
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Tschuor F Zini E Schellenberg S Wenger M Kaufmann K Furrer D Lutz TA Reusch CE 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2011,25(1):83-89
Background: Cats with diabetes mellitus frequently achieve clinical remission, suggesting residual β‐cell function. Responsiveness of β‐cells to arginine persists the longest during diabetes progression, making the intravenous arginine stimulation test (IVAST) a useful tool to assess residual insulin and glucagon secretion. Hypothesis: Diabetic cats with and without remission will have different arginine‐induced insulin or glucagon response. Animals: Seventeen cats with diabetes, 7 healthy cats. Methods: Blood samples collected on admission and during subsequent IVAST. Glucose, insulin, and glucagon were measured. Response to IVAST was assessed by calculating the insulin and glucagon area under the curve (AUC) and the AUC glucagon‐to‐insulin ratio. Diabetic cats were treated with insulin and were followed for 18 weeks. Remission was defined as normoglycemia and disappearance of clinical signs of diabetes for ≥4 weeks, without requiring insulin. Results: Seven diabetic cats (41%) achieved remission. On admission, blood glucose concentration was significantly lower in cats with remission (median, 389 mg/dL; range, 342–536 mg/dL) than in those without remission (median, 506 mg/dL; range, 266–738 mg/dL). After IVAST, diabetic cats with remission had higher AUC glucagon‐to‐insulin ratios (median, 61; range, 34–852) than did cats without remission (median, 26; range, 20–498); glucose, insulin, and glucagon AUCs were not different. Diabetic cats had lower insulin AUC than did healthy cats but comparable glucagon AUC. Conclusions and Clinical Importance: Diabetic cats with and without remission have similar arginine‐stimulated insulin secretion on admission. Although cats with remission had lower blood glucose concentrations and higher AUC glucagon‐to‐insulin ratios, large overlap between groups prevents use of these parameters in clinical practice. 相似文献
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Contribution of Medicago sativa to the productivity and nutritive value of forage in semi‐arid grassland pastures
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R. Klabi T. H. Bell C. Hamel A. Iwaasa M. P. Schellenberg M. St‐Arnaud 《Grass and Forage Science》2018,73(1):159-173
The inclusion of legumes in semi‐arid native grasslands may promote the productivity and nutritive value of forage. This study was designed to assess the effect of legumes (the introduced legume Medicago sativa or the native legume Dalea purpurea) and soil P fertility (addition of 0, 50, or 200 P2O5 kg/ha at seeding) on the dry matter and nutrient content of native grasses mixtures, compared with the commonly used introduced forage grass Bromus biebersteinii grown with M. sativa. Plant harvests were performed in September 2008, July 2009 and September 2009. Plants nutrient content, δ15N value and dry matter were analysed. Results show that the M. sativa enhanced the N and P concentrations of native grass mixtures early in the summer, as well as the N concentration in Bouteloua gracilis in late summer of the driest year, 2009. The higher AM fungal diversity promoted by M. sativa was positively correlated with the dry matter and nitrogen uptake of M. sativa and with the P concentration of native grasses, in early summer. Overall, this study shows that M. sativa promoted beneficial AM fungal taxa and improved forage production in the semi‐arid prairies. 相似文献
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Daniel Goitom Asfaha Christophe R. Quétel Freddy Thomas Micha Horacek Bernhard Wimmer Gerhard Heiss Christian Dekant Peter Deters-Itzelsberger Stefan Hoelzl Susanne Rummel Christophe Brach-Papa Marleen Van Bocxstaele Eric Jamin Malcolm Baxter Katharina Heinrich Simon Kelly Daniela Bertoldi Luana Bontempo Federica Camin Roberto Larcher Matteo Perini Andreas Rossmann Antje Schellenberg Claus Schlicht Heinz Froeschl Jurian Hoogewerff Henriette Ueckermann 《Journal of Cereal Science》2011
The aim of this work (from the FP6 project TRACE) was to develop methods based on the use of geochemical markers for the authentication of the geographical origin of cereal samples in Europe (cf. EC regulations 2081/92 and 1898/06). For the first time, the potential usefulness of combining n(87Sr)/n(86Sr) and δ13C, δ15N, δ18O and δ34S isotopic signatures, alone or with key element concentrations ([Na], [K], [Ca], [Cu] and [Rb], progressively identified out of 31 sets of results), was investigated through multiple step multivariate statistics for more than 500 cereal samples collected over 2 years from 17 sampling sites across Europe representing an extensive range of geographical and environmental characteristics. 相似文献