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This study was conducted to record the ideal source and level of alkali treatment to treat jatropha meal (JM) and to determine the effect of inclusion of variously processed JM (pJM) on nutrient intake, digestibility, blood metabolites and hormonal status in goats. The JM was treated with 10 g/kg sodium chloride and 5 g/kg calcium hydroxide. The content of phorbol ester and hemagglutination (HA) activity of JM and pJM were assessed. A feeding trial for 90 days was conducted in short-haired multipurpose goats (n?=?15; five per group). The experimental animals were offered oat (Avena sativa) straw ad libitum throughout the experimental period of 90 days. Each group was assigned to one of the three diets, viz. R1—soybean meal, R2—sodium chloride (10 g/kg dry matter, DM), and R3—calcium hydroxide (5 g/kg DM), with pJM substituting 250 g/kg DM of crude protein (CP) of control (R1). At the end of the feeding period, digestion trial of 7 days was conducted. Blood samples were collected at the end of the experimental period to assess the blood metabolites and hormonal status. The phorbol ester and HA activity were reduced considerably in pJM. The intake of DM, organic matter, CP, and nitrogen-free extract were comparable among all the groups. However, the intake of ether extract was significantly higher in pJM-fed groups. The hemoglobin, packed cell volume, serum urea, triiodothyronine and testosterone contents decreased in R2 and R3 as compared to R1. Concentration of glucose and activity of serum glutamic pyruvic transaminase and lactate dehydrogenase increased (P?<?0.01) in goats fed pJM. It was concluded that phorbol ester content and HA activity markedly decreased by processing JM with sodium chloride and calcium hydroxide. However, they were not reduced to the levels of safe feeding, as reflected in unusual values of blood metabolites among the experimental animals.  相似文献   
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A field experiment was conducted to study the effect of silicon (diatomaceous earth, DE) fertilization on growth, yield, and nutrient uptake of rice during the kharif season of 2012 and 2013 in the new alluvial zone of West Bengal, India. Results showed that application of silicon significantly increased grain and straw yield as well as yield-attributing parameters such as plant height (cm), number of tillers m?2, number of panicle m?2, and 1000-grain weight (g) of rice. The greatest grain and straw yields were observed in the treatment T6 (DE at 600 kg ha?1 in combination with standard fertilizer practice (SFP). The concentration and uptake of silicon, nitrogen (N), phosphorus (P), and potassium (K) in grain and straw were also greater under this treatment compared to others. It was concluded that application of DE at 600 kg ha?1 along with SFP resulted increased grain, straw, and uptake of NPK.  相似文献   
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Cucumis setosus Cogn. is a rare, endemic, wild gathered or semi-domesticated vegetable restricted to Maharashtra state and border districts of adjoining states in India. Herbarium and literature survey shows that it is poorly collected and inadequately studied. Morphological characters, basic chromosome number and crossability barriers indicate that Cucumis setosus is a valid species, distinct from C. sativus and endemic to western India. Its morphology, basic cytology, crossability relationship with other Cucumis species, taxonomy, distribution, ecology, conservation, economic importance and viability under cultivation are discussed. Besides, a key to distinguish it from C. sativus var. hardwickii (wild and feral form of C. sativus) and other species having sympatric distribution in the area is also presented. Absence of bitter principle in the fruits makes it a potential germplasm for melon and cucumber improvement as well as direct domestication as a future crop.  相似文献   
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Asian cultivated rice shows allelic variation in sodium transporter, OsHKT1;5, correlating with shoot sodium exclusion (salinity tolerance). These changes map to intra/extracellularly-oriented loops that occur between four transmembrane-P loop-transmembrane (MPM) motifs in OsHKT1;5. HKT1;5 sequences from more recently evolved Oryza species (O. sativa/O. officinalis complex species) contain two expansions that involve two intracellularly oriented loops/helical regions between MPM domains, potentially governing transport characteristics, while more ancestral HKT1;5 sequences have shorter intracellular loops. We compared homology models for homoeologous OcHKT1;5-K and OcHKT1;5-L from halophytic O. coarctata to identify complementary amino acid residues in OcHKT1;5-L that potentially enhance affinity for Na+. Using haplotyping, we showed that Asian cultivated rice accessions only have a fraction of HKT1;5 diversity available in progenitor wild rice species (O. nivara and O. rufipogon). Progenitor HKT1;5 haplotypes can thus be used as novel potential donors for enhancing cultivated rice salinity tolerance. Within Asian rice accessions, 10 non-synonymous HKT1;5 haplotypic groups occur. More HKT1;5 haplotypic diversities occur in cultivated indica gene pool compared to japonica. Predominant Haplotypes 2 and 10 occur in mutually exclusive japonica and indica groups, corresponding to haplotypes in O. sativa salt-sensitive and salt-tolerant landraces, respectively. This distinct haplotype partitioning may have originated in separate ancestral gene pools of indica and japonica, or from different haplotypes selected during domestication. Predominance of specific HKT1;5 haplotypes within the 3 000 rice dataset may relate to eco-physiological fitness in specific geo-climatic and/or edaphic contexts.  相似文献   
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Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive hormone production and unrestrained cell proliferation; the mechanisms linking these events are unknown. We identify two recurrent somatic mutations in and near the selectivity filter of the potassium (K(+)) channel KCNJ5 that are present in 8 of 22 human APAs studied. Both produce increased sodium (Na(+)) conductance and cell depolarization, which in adrenal glomerulosa cells produces calcium (Ca(2+)) entry, the signal for aldosterone production and cell proliferation. Similarly, we identify an inherited KCNJ5 mutation that produces increased Na(+) conductance in a Mendelian form of severe aldosteronism and massive bilateral adrenal hyperplasia. These findings explain pathogenesis in a subset of patients with severe hypertension and implicate loss of K(+) channel selectivity in constitutive cell proliferation and hormone production.  相似文献   
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Coronary artery disease (CAD) is the leading cause of death worldwide and is commonly caused by a constellation of risk factors called the metabolic syndrome. We characterized a family with autosomal dominant early CAD, features of the metabolic syndrome (hyperlipidemia, hypertension, and diabetes), and osteoporosis. These traits showed genetic linkage to a short segment of chromosome 12p, in which we identified a missense mutation in LRP6, which encodes a co-receptor in the Wnt signaling pathway. The mutation, which substitutes cysteine for arginine at a highly conserved residue of an epidermal growth factor-like domain, impairs Wnt signaling in vitro. These results link a single gene defect in Wnt signaling to CAD and multiple cardiovascular risk factors.  相似文献   
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Knowledge about soil organic carbon (SOC) stock and its allocation into different pools is important for global food and environmental security. Accordingly, an attempt is made in the present study to investigate into the dynamics of SOC pools i.e. total soil organic carbon (TOC), oxidisable organic carbon (OC) and its different fractions viz. very labile (CVL), labile (CL), less labile (CLL) and non-labile (CNL) in soils under a 26 years old long-term experiment with rice (Oryza sativa L) – wheat (Triticum aestivum L) cropping system on Inceptisols under humid agro-climatic region of India with different soil management practices (control, 100% recommended dose of NPK, and 50% recommended dose of NPK + 50% N through farmyard manure (FYM). Of the several pools analyzed, a higher proportion of C was found in labile pool followed by very labile, non-labile, and less labile ones constituting about 46, 26.5, 20 and 7.3% of the total organic C at surface soil. The NPK+FYM treatment was found to have higher SOC pools, lability index (LI), recalcitrance indices and stratification ratio as compared to others. Results indicated that balanced fertilization with inorganic and organics is important for maintaining overall sustainability of the rice-wheat system.  相似文献   
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Pedotransfer functions are classes of models used to estimate soil water holding characteristics based on commonly measured soil composition data as well as other soil characteristics. These models are important on their own but are particularly useful in modeling agricultural crop yields where only soil composition is known. In this article, an additive, multivariate spatial process model is introduced that offers the flexibility to capture the complex structure typical of the relationship between soil composition and water holding characteristics, thus defining a new form of pedotransfer function. Further, the uncertainty in the soil water characteristics is quantified in a manner to simulate ensembles of soil water profiles. Using this capability, a small study is conducted with the CERES maize crop model to examine the sources of variation in the yields of maize. Here it is shown that the interannual variability of weather is a more significant source of variation in crop yield than the uncertainty in the pedotransfer function for two specific soil textures.  相似文献   
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