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Sawada Y Yanai T Nakagawa H Tsukamoto Y Tamagawa Y Yokoi S Yanagi M Toya T Sugizaki H Kato Y Shirakura H Watanabe T Yajima Y Kodama S Masui A 《Pest management science》2003,59(1):49-57
Nineteen analogues were synthesized by modifying the tert-butylhydrazine moieties of N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide and N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methylchromane-6-carbohydrazide (chromafenozide), and the synthesized analogues were evaluated for their insecticidal activity against Spodoptera litura F. While all of the synthesized analogues had insecticidal activity inferior to those of the lead compounds, several of the analogues nonetheless showed high insecticidal activity. Chromafenozide has shown very high selectivity toward lepidopteran species. 相似文献
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Tomoko Maeda Tetsu Hashimoto Masashi Minoda Shin‐ichiro Tamagawa Naofumi Morita 《Cereal Chemistry》2003,80(6):722-727
Thermostable mutant α‐amylases (21B, M111, and M77) with various degrees of thermostability were purified from Bacillus amyloliquefaciens F and used as improvers for breadmaking. Test baking with the mutant enzymes was conducted using the long fermentation sponge‐dough method. Addition of an appropriate amount of mutant α‐amylases to the ingredients distinctly increased the specific volume of the bread and improved the softness of breadcrumb as compared with the addition of Novamyl (NM), an exo‐type α‐amylase. M77 was the most effective in retarding the staleness of breadcrumb. The softness of breadcrumb during storage, however, was not correlated with the thermostability. All mutant α‐amylases weakened the mixing property of the dough, whereas they strengthened the property of fermented dough. Especially, M77 and NM had different effects on the dough properties, but their bread qualities were similar to each other. The strong tolerance of M77 dough to the long baking process might be due to the production of hydrolyzed starches, oligosaccharides in the range of maltopentaose to maltohexaose, as compared with NM. Therefore, in the light of present findings, these mutant α‐amylases are possible substitutes for NM as bread improvers. 相似文献
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Flocculation and dispersion of colloidal particles of nine inorganic paddy soils were studied mainly based on turbidity measurements of the suspensions of soils which were previously incubated at 28°C under in vitro waterlogged conditions. After 1-week of incubation, the turbidity of the soils except for 1) two soils containing larger amounts of sodium salts and 2) one soil containing larger amounts of Fe and Al oxides, significantly decreased, and colloidal particles flocculated with 1) a decrease in soil Eh and 2) an increase in electric conductivity (EC). During the 3- to 4-week period of waterlogging, the turbidity of the three soils significantly increased with the 1) decrease in EC and 2) increase in pH of the soils although the Eh remained low. Infrared (IR) absorption analysis showed that the suspended colloidal particles consisted of layer silicates from respective soil clays. Oxidation of suspensions of waterlogged soils by air-bubbling led to an increase in turbidity with the 1) increase in Eh, and 2) decrease in pH, EC, and water-soluble Fe2+ concentration. It was suggested that the stability of the soil colloidal suspensions was affected by soil reduction with alterations in ionic species and their concentrations at clay surfaces and in soil solutions. 相似文献
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In humans, chronic ethanol consumption leads to a characteristic set of changes to the metabolism of lipids in the liver that
is referred to as an "alcoholic fatty liver (AFL)". In severe cases, these metabolic changes result in the enlargement and
fibrillization of the liver and are considered risk factors for cirrhosis and liver cancer. Clock-mutant mice have been shown to display abnormal lipid metabolism and alcohol preferences. To further understand the potential
interactions between ethanol consumption, lipid metabolism, and the circadian clock, we investigated the effect of chronic
ethanol intake on the lipid metabolism of Clock-mutant mice. We found that ethanol treatment produced a number of changes in the liver of Clock-mutant mice without impacting the wild-type controls. First, we found that 8 weeks of exposure to ethanol in the drinking
water increased the weight of the liver in Clock-mutant mice. Ethanol treatment also increased triglyceride content of liver in Clock-mutant and wild-type mice. This increase was larger in the mutant mice. Finally, ethanol treatment altered the expression
of a number of genes related to lipid metabolism in the Clock-mutant mice. Interestingly, this treatment did not impact circadian clock gene expression in the liver of either genotype.
Thus, ethanol produces a number of changes in the liver of Clock-mutant mice that are not seen in the wild-type mice. These changes are consistent with the possibility that disturbance of
circadian rhythmicity associated with the Clock mutation could be a risk factor for the development of an alcoholic fatty liver. 相似文献
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