Changes in landscape naturalness derived from a historical land register—a case study from NE Germany     

Florian Jansen  Stefan Zerbe  Michael Succow 《Landscape Ecology》2009,24(2):185-198

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Pancreatic Polypeptide and Insulin-Secreting Tumor in a Dog With Duodenal Ulcers and Hypertrophic Gastritis     

Carole A. Zerbe DVM  MS    Timothy R. Boosinger DVM  PhD    J. H. Grabau DVM    J. M. Pletcher DVM  Thomas M. O''Dorisio MD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1989,3(3):178-182

A 7-year-old spayed female Cocker Spaniel was hospitalized with a history of chronic vomiting, anorexia, and weight loss. Laboratory abnormalities included leukocytosis, metabolic alkalosis, hypoglycemia, hypoproteinemia, and hyperinsulinemia. Gastroscopy and ultrasonography revealed multiple gastric masses and a possible pancreatic mass, respectively. Examination of tissues obtained at necropsy showed a pancreatic adenocarcinoma with hepatic metastasis, gastric hypertrophy, and multiple duodenal ulcers. Immunocytochemical staining of the neoplasia was positive for pancreatic polypeptide (PP) and insulin and negative for gastrin, calcitonin, adrenocorticotropic hormone (ACTH), serotonin, L-enkephalin, chromagranin, glucagon, and somatostatin. Subsequent serum gastrin and PP assays showed a fasting hypergastrinemia with a normal response of gastrin to provocative testing and extremely increased PP values. The high PP values may have resulted in the vomiting and gastrointestinal ulceration. A PP-secreting tumor has not previously been reported in the dog.  相似文献   

Multihormonal pancreatic endocrine tumor in a dog with duodenal ulcers and hypertrophic gastropathy     

T R Boosinger  C A Zerbe  J H Grabau  J M Pletcher 《Veterinary pathology》1988,25(3):237-239

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Disinfection of animal enclosures, pasture and soil     

W Stellmacher  J Zerbe 《Monatshefte für Veterin?rmedizin》1971,26(23):881-885

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Isolation and cryopreservation of functionally competent equine leucocytes     

Zerbe H  Castilho LF  Engelke F  Mattos RC  Schuberth HJ  Klug E  Leibold W 《Journal of veterinary medicine. A, Physiology, pathology, clinical medicine》2003,50(4):179-184

Sufficient numbers of functionally competent polymorphonuclear neutrophil granulocytes (PMN) seem to be of major importance during the course of equine endometritis. In this study, we wanted to establish a method for cryopreservation of functionally competent neutrophils for an intended local endometritis therapy in mares. The separation of leucocytes by hypotonic lysis of whole blood from clinically healthy mares was superior to the separation by dextrose sedimentation. After suspension of the cells in the cryoprotective solution [equine plasma with 5% (v/v) dimethyl sulphoxide (DMSO)], the leucocytes were frozen in liquid nitrogen. A temperature gradient with low cooling velocity (1 degree C/min between 4 and -70 degrees C) resulted in highest numbers of viable cells after thawing. Thawed PMN had a high phagocytic capacity for opsonized streptococci. Their ability to generate reactive oxygen species (ROS) after stimulation with a phorbol ester was even higher than that of freshly isolated PMN and was preserved up to 6 h after thawing. The results of this study indicate that cryopreservation of PMN may provide viable and functionally competent neutrophils for therapeutic use in mares susceptible to endometritis.  相似文献   

"Emergency splitting" of the teat canal--a therapeutic procedure in case of concurrent occurrence of acute thelitis and severe mastitis     

Korff B  Ahlers D  Zerbe H 《DTW. Deutsche tier?rztliche Wochenschrift》2003,110(7):290-294

In case of concurrent acute thelitis and severe mastitis, an immediate surgery of the stenosis ("emergency splitting") might be justified in order to improve milkability as a prerequisite for the removal of pathological milk secretion and therapy, successful mastitis therapy. The aim of this study was to compare the milkability and the clinical cure rate of mastitis between Group A (n = 19, cows with stenosis, thelitis and mastitis) and Group B (n = 19, cows with stenosis, with or without clinical mastitis, but without acute thelitis) following surgery of the papillary duct using a cutting instrument (Danish cannula model with a double cutting edge). In most cases, milkability was restored at the end of the treatment in both groups (Group A: 89.5%; Group B: 100%). In this time period nine of 19 quarters with mastitis in Group A were clinically cured (47%). Six month after the surgery, the animal owners considered the milkability as very good in 70% and 72% of the cases in Group A and Group B, respectively. However, "emergency splitting" led to a more intensive and longer postsurgical treatment. The average duration of total treatment (day of surgery plus 6 days of obligate postsurgical treatment plus additional treatment days) was 7.4 and 6.7 days in Group A and Group B, respectively. Furthermore, the higher expenditure was due to the more costly mastitis therapy. During the six month following surgery, only one cow of Group A had to be culled due to persistent mastitis and two cows because of insufficient milkability.  相似文献   

Stellt die potentielle natürliche Vegetation (PNV) eine sinnvolle Zielvorstellung für den naturnahen Waldbau dar?     

Dr. S. Zerbe 《European Journal of Forest Research》1996,116(1-6):1-15

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Influence of different forest conversion strategies on ground vegetation and tree regeneration in pine (<Emphasis Type="Italic">Pinus sylvestris</Emphasis> L.) stands: a case study in NE Germany     

Stefan Zerbe  Daria Kreyer 《European Journal of Forest Research》2007,126(2):291-301

The conversion of anthropogenic into more natural, self-regenerating forests is one of the major objectives of forestry throughout Europe. In this study, we present investigations on permanent plots with different silvicultural treatment in NE German pine stands. Management of old-growth pine stands on acidic and nutrient-poor sandy sites differs in fencing, thinning, and planting of certain tree species. The investigations were carried out on the community, population, and individual level of the pine forest ecosystems. Thus, vegetation changes, size and height of tree populations, and height increment of tree individuals were observed over a time span of 6 years. Special attention was paid to short-lived tree species such as, e.g., Frangula alnus and Sorbus aucuparia, as well as to Fagus sylvatica as one of the most typical forest tree species of Central Europe. Vegetation changes are interpreted as a consequence of natural regeneration of formerly degraded forest sites, involving an increase in nutrient availability. High browsing pressure can be considered as a key factor for the inhibition of tree seedlings and growth of saplings. Some Sorbus aucuparia individuals, however, succeeded in growing out of the browsing height also in unfenced stands. Few found specimens of Fagus sylvatica proved that this species is able to establish spontaneously on these relatively dry, acidic sites under continental climate influence. Such natural regeneration processes, also including spontaneous rejuvenation of trees, can be integrated into silviculture as passive forest conversion management. An active management like thinning of stands, planting of trees, and fencing can accelerate forest conversion with regard to height growth and species number of trees.  相似文献   

New mosquito larvicidal tetranortriterpenoids from Turraea wakefieldii and Turraea floribunda     

Ndung'u MW  Kaoneka B  Hassanali A  Lwande W  Hooper AM  Tayman F  Zerbe O  Torto B 《Journal of agricultural and food chemistry》2004,52(16):5027-5031

The crude methanol extracts of the root barks of Turraea wakefieldii and Turraea floribunda were found to show mosquito larvicidal activity against third-instar larvae of Anopheles gambiae sensu stricto. Four new limonoids comprising a vilasininoid 1 and three havanensinoids 2-4 were isolated from the chloroform fractions of the methanol extracts of T. wakefieldii and T. floribunda, respectively. The structures of the compounds were elucidated by NMR spectroscopy. Compounds 1, 2, and 4 had LD50 values of 7.1, 4.0, and 3.6 ppm, respectively, and were more potent than azadirachtin, which had an LD50 value of 57.1 ppm when tested against larvae of A. gambiae.  相似文献   

Thyroid Hormone Concentrations In Critically III Canine Intensive Care Patients     

Denise A. Elliott  Lesley G. King  Carole A. Zerbe 《Journal of Veterinary Emergency and Critical Care》1995,5(1):17-23

Alterations in thyroid indices in critically ill dogs were studied retrospectively to determine the incidence of the euthyroid sick syndrome and to assess its prognostic relevance to survival. Sixty-seven dogs were classified as euthyroid bases on a TSH stimulation test. Forty-one of 67 (61%) of the euthyroid dogs had low baseline serum T₄ concentrations (<1.5 ug/dl) and 38 of 67 (56%) of the euthyroid dogs had low baseline serum T₃ concentrations (<75 ng/dl). There was no significant difference between either the baseline or the post-stimulation serum T₄ concentrations when values of dogs that survived were compared with those that died. There was, however, a significant difference (P<0.05) between both the baseline and the post-stimulation values for T3 when survivors (100.3± 81 ng/dl, 143± 66 ng/dl) and non-survivors (64.2 ± 17.1 ng/dl, 96.6 ± 38.3 ng/dl) were compared. The euthyroid sick syndrome occurs commonly in critically ill dogs. Further, the extent of depression of serum concentrations of T₃ may be correlated to mortality.  相似文献