The potential use of plasma glutamate dehydrogenase activity for the evaluation of hepatic disease in the cockatiel (Nymphicus hollandicus)     

Battison AL  Buczkowski S  Archer FJ 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1996,25(2):43-47

A reference interval for plasma glutamate dehydrogenase (GD) (E.C. 1.4.1.3) activity, of 0-8 IU/L, was established for the cockatiel (Nymphicus hollandicus). An automated modification of a commercial manual assay was used. This enzyme is considered liver specific in humans and numerous domestic animals, due to its organ distribution. A similar distribution was found in cockatiels in this study. Maximal enzyme activity was recovered from liver and kidney homogenate supernatants. Minimal activity was detected in skeletal muscle preparations. These results suggest a potential use for plasma GD activity in the evaluation of hepatocelluar injury/necrosis in cockatiels.  相似文献   

Idiopathic eosinophilic colitis lesions of the equine small (descending) colon          下载免费PDF全文

M. P. de Bont  A. J. Malbon  R. Blundell  D. C. Archer 《Equine Veterinary Education》2018,30(9):466-471

Five horses with a primary surgical lesion of the small (descending) colon were diagnosed with eosinophilic colitis based on visual and histopathological examination. These were evident as visibly striking, hyperaemic, focal lesions of the small colon, with serosal petechiation, oedema and marked thickening of the intestinal wall at the site. Areas of focal necrosis were also evident. The gross appearance of the lesions were considered to be sufficiently severe in all cases to merit resection, due to concerns about intestinal necrosis and septic peritonitis. An inability to fully exteriorise the affected portion of intestine to perform a resection and anastomosis necessitated intraoperative euthanasia of one horse. A total of three horses survived to hospital discharge. Eosinophilic colitis lesions are a rare cause of severe small colon disease, but should be considered in cases with similar visual characteristics.  相似文献   

Evaluation of urinary biomarkers for azotaemic chronic kidney disease in cats          下载免费PDF全文

T. L. Williams  J. Archer 《The Journal of small animal practice》2016,57(3):122-129

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Effect of prewarming EDTA blood samples to 37°C on platelet count measured by Sysmex XT‐2000iV in dogs,cats, and horses          下载免费PDF全文

Tim L. Williams  Joy Archer 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2016,45(3):444-449

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The Effects of Cyclosporine and Aspirin on Platelet Function in Normal Dogs          下载免费PDF全文

J. Thomason  T. Archer  R. Wills  S. Press  A. Mackin 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(4):1022-1030

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Evaluating the effects of supplementing Saccharomyces cerevisiae in the feed or drinking water on stress susceptibility of broilers     

E.B. Sobotik  J.R. Nelson  H.O. Pavlidis  G.S. Archer 《The Journal of Applied Poultry Research》2022,31(1):100220

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On the distribution of tree growth stresses     

Professor R. R. Archer 《Wood Science and Technology》1985,19(3):259-276

Summary A plane strain pure bending elastic model is used to predict stress states in a cylindrically orthotropic cylinder due to asymmetric strain distributions continously induced at the periphery. A general solution for the stress states related to each component of the strain distribution expanded in a Fourier series is given. Details of solutions for eleven representative tree species are given. Also the change of curvature of a stem caused by a measured peripheral strain distribution is computed for a given period of growth.  相似文献   

Residual stresses caused by growth stresses within a stem with radially varying spiral grain angle – two numerical solution approaches: 1) finite element method and 2) transfer matrix method     

S. Skatter  R. R. Archer 《Wood Science and Technology》2001,35(1-2):57-71

Two numerical methods, the Finite Element (FE) method and the Transfer Matrix (TM) method, have been applied to derive a solution for residual stresses in a stem. The source of stress is the maturation strains in new wood cells, which give rise to growth stresses. The methods are generally applicable to the case of spiral grain with a grain angle varying with radius, which often is the case in trees. Also, the methods allow for the elastic constants to vary with the radius, which is important to model, for example, juvenile wood. The numerical solutions are checked against an analytical solution in the case of a constant grain angle, and are found to coincide. In addition, the two methods are shown to independently produce the same stress distribution for one pattern of grain angle variation. This shows that the methods are reliable, and they will be used for obtaining a wider range of solutions in a subsequent paper. Received: 13 January 1998  相似文献   

An extension of Jacobs' method for measuring residual growth strains in logs     

I. L. Post  J. C. Atherton  C. P. Vendhan  Professor R. R. Archer 《Wood Science and Technology》1980,14(4):289-296

Summary Previous methods for measuring residual longitudinal growth strain distributions in logs are reviewed. An extension is given of Jacobs' method for measuring growth strains which yields residual strain information at many points in the cross section other than along the diametrical plank. Some of the longitudinal growth strain distributions measured using the new method are presented.This work was supported in part by NSF Grant ENG-74-02428  相似文献   

Oral Cyclosporine Treatment in Dogs: A Review of the Literature     

T.M. Archer  D.M. Boothe  V.C. Langston  C.L. Fellman  K.V. Lunsford  A.J. Mackin 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2014,28(1):1-20

Cyclosporine is an immunomodulatory drug used to treat an increasing spectrum of diseases in dogs. Cyclosporine is a calcineurin inhibitor, ultimately exerting its inhibitory effects on T‐lymphocytes by decreasing production of cytokines, such as interleukin‐2. Although, in the United States, oral cyclosporine is approved in dogs only for treatment of atopic dermatitis, there are many other indications for its use. Cyclosporine is available in 2 oral formulations: the original oil‐based formulation and the more commonly used ultramicronized emulsion that facilitates oral absorption. Ultramicronized cyclosporine is available as an approved animal product, and human proprietary and generic preparations are also available. Bioavailability of the different formulations in dogs is likely to vary among the preparations. Cyclosporine is associated with a large number of drug interactions that can also influence blood cyclosporine concentrations. Therapeutic drug monitoring (TDM) can be used to assist in attaining consistent plasma cyclosporine concentrations despite the effects of varying bioavailability and drug interactions. TDM can facilitate therapeutic success by guiding dose adjustments on an individualized basis, and is recommended in cases that do not respond to initial oral dosing, or during treatment of severe, life‐threatening diseases for which a trial‐and‐error approach to dose adjustment is too risky. Pharmacodynamic assays that evaluate individual patient immune responses to cyclosporine can be used to augment information provided by TDM.  相似文献