Recovery of brodifacoum in vomitus following induction of emesis in dogs that had ingested rodenticide bait     

KH Parton  EK Willson  MG Collett  LH Booth 《New Zealand veterinary journal》2018,66(1):41-43

AIM: To assess the benefit of inducing emesis in dogs that have ingested rodenticide bait containing brodifacoum (BDF), by determining the amount of BDF in bait recovered from the vomitus relative to the estimated amount consumed.

METHODS: Between 2014 and 2015 samples of vomitus from seven dogs that ingested rodenticide baits containing BDF were submitted by veterinarians in New Zealand. All seven dogs had been given apomorphine by the veterinarian and vomited within 1 hour of ingesting the bait. Some or all of the bait particles were retrieved from each sample and were analysed for concentrations of BDF using HPLC. Based on estimations of the mass of bait consumed, the concentration of BDF stated on the product label, and the estimated mass of bait in the vomitus of each dog, the amount of BDF in the vomited bait was calculated as a percentage of the amount ingested.

RESULTS: For five dogs an estimation of the mass of bait ingested was provided by the submitting veterinarian. For these dogs the estimated percentage of BDF in the bait retrieved from the vomitus was between 10–77%. All dogs were well after discharge but only one dog returned for further testing. This dog had a normal prothrombin time 3 days after ingestion.

CONCLUSIONS AND CLINICAL RELEVANCE: The induction of emesis within 1 hour of ingestion can be a useful tool in reducing the exposure of dogs to a toxic dose of BDF. The BDF was not fully absorbed within 1 hour of ingestion suggesting that the early induction of emesis can remove bait containing BDF before it can be fully absorbed.  相似文献   

倾斜圆盘勺式玉米精密排种器的试验研究   总被引：13，自引：5，他引：13  

李成华  马成林  于海业  KH.Kromer 《农业机械学报》1999,30(2):38-42

为与铲式成穴器的结构特点相适应,选择倾斜圆盘勺式玉米精密排种器作为打穴播种机的排种机构。在分析分种勺结构特点和分种性能的基础上,通过试验确定了排种器倾角和转速对不同玉米种子分种性能的影响,并采用机械优化设计的方法对参数进行了优化组合。  相似文献   

胰蛋白酶对叶蛋白水解作用的研究     

邱业先  汪金莲  邹长媛  谢宝平 《江西农业大学学报》1998,(4)

以植物叶蛋白浓缩物为材料,用胰蛋白酶在不同条件下对其进行水解。结果表明,胰蛋白酶作用于植物叶蛋白,其最佳水解温度为４０℃;最佳水解ｐＨ值为９;水解程度随酶量和反应时间增加而增加;各种不同种类的植物叶蛋白在相同条件下被胰蛋白酶水解的程度基本一致,证明了植物叶蛋白易被动物体内蛋白酶分解。  相似文献   

Evaluation of the sensitivity of reverse-transcription polymerase chain reaction to detect porcine reproductive and respiratory syndrome virus on individual and pooled samples from boars.     

Albert Rovira  Travis Clement  Jane Christopher-Hennings  Bob Thompson  Mark Engle  Darwin Reicks  Claudia Mu?oz-Zanzi 《Journal of veterinary diagnostic investigation》2007,19(5):502-509

  相似文献   

Recruitment and early growth of eastern white pine (Pinus strobus) regeneration after partial cutting and site preparation     

Burgess  Darwin; Wetzel  Suzanne 《Forestry》2002,75(4):419-423

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Mercury antagonists: protection of plants against vapor injury by thiamine and other compounds     

S. M. Siegel  B. Z. Siegel  Leeann Sheldon  Elizabeth Yaeger  Darwin Chang 《Water, air, and soil pollution》1986,27(3-4):243-246

Mercury vapor-induced abscission ofColeus cuttings was prevented by Thiamine, other organo-S (Se) compounds and selenite, but not by common sugar metabolites, amino acids, non-auxin growth regulators and selenate. Protection was also afforded to other plants including ferns and gymnosperms. Thus the compounds that protect plants against Hg intoxication correspond to the Hg antagonists known in animals including man.  相似文献   

THE ADDRESS OF THE PRESIDENT OF THE BRITISH ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE--I     

Darwin F 《Science (New York, N.Y.)》1908,28(716):353-362

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THE AIMS AND METHODS OF EUGENICAL SOCIETIES     

Darwin L 《Science (New York, N.Y.)》1921,54(1397):313-323

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The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide     

Darwin KH  Ehrt S  Gutierrez-Ramos JC  Weich N  Nathan CF 《Science (New York, N.Y.)》2003,302(5652):1963-1966

The production of nitric oxide and other reactive nitrogen intermediates (RNI) by macrophages helps to control infection by Mycobacterium tuberculosis (Mtb). However, the protection is imperfect and infection persists. To identify genes that Mtb requires to resist RNI, we screened 10,100 Mtb transposon mutants for hypersusceptibility to acidified nitrite. We found 12 mutants with insertions in seven genes representing six pathways, including the repair of DNA (uvrB) and the synthesis of a flavin cofactor (fbiC). Five mutants had insertions in proteasome-associated genes. An Mtb mutant deficient in a presumptive proteasomal adenosine triphosphatase was attenuated in mice, and exposure to proteasomal protease inhibitors markedly sensitized wild-type Mtb to RNI. Thus, the mycobacterial proteasome serves as a defense against oxidative or nitrosative stress.  相似文献   

Economic valuation of acidic deposition damages: Preliminary results from the 1985 NAPAP assessment     

J. M. Callaway  R. F. Darwin  R. J. Nesse 《Water, air, and soil pollution》1986,31(3-4):1019-1034

This paper presents estimates of the monetary value of the biophysical damages caused by acid deposition for the National Acid Precipitation Assessment Program's 1985 Assessment. Economic damages are estimated for four effect areas: commercial agriculture, forests, recreational fishing and selected types of materials. The preliminary nature of the value of the estimated damages in each area is emphasized. The estimated values should be interpreted with appropriate regard for the uncertainties about the physical effects of acid deposition and the assumptions in the economic analysis.  相似文献