Biochemical,physiological and production indices related to fat metabolism in the laying fowl at various stages of physiological development     

A. R. Neill  K. G. Reichmann  J. K. Connor 《British poultry science》1977,18(3):315-324

1. The significance of fat accumulation during physiological development of layers was studied using White Leghorn x Australorp pullets from 12 weeks of age.

2. Liver fat, carcass fat, liver weight and body weight increased markedly at the onset of sexual maturity.

3. Within the liver, the protein to DNA ratio did not alter significantly during development; glycogen was not consistently depleted by egg production.

4. Liver fat content was significantly correlated with carcass fat, liver weight and DNA concentration, and plasma total lipid and cholesterol, independent of stage of development; with body weight, liver protein, moisture, and protein to DNA ratio, excluding the period prior to commencement of sexual maturation; and with plasma phospholipid during lay.

5. Obesity was a feature of faster growing fowls which matured earlier, consumed more, utilised food less efficiently for egg production and produced fewer saleable eggs.  相似文献   

Pasteurella haemolytica in the bovine reproductive tract.          下载免费PDF全文

S D Neill  W J McCaughey  J J O'Brien    W A Ellis 《The Canadian veterinary journal. La revue veterinaire canadienne》1981,22(9):294

  相似文献   

Assessment of defined antigens for the diagnosis of bovine tuberculosis in skin test-reactor cattle   总被引：17，自引：0，他引：17  

Pollock JM  Girvin RM  Lightbody KA  Clements RA  Neill SD  Buddle BM  Andersen P 《The Veterinary record》2000,146(23):659-665

The continued use of purified protein derivative (PPD) tuberculin is considered to be the main factor which limits the specificity of diagnostic tests for bovine tuberculosis (TB). This study evaluated a whole blood interferon-gamma (IFN-gamma) assay and compared the diagnostic potential of PPD with two tuberculosis-specific antigens, ESAT-6 and MPB70. To provide estimates of sensitivity and specificity, responses were measured in 180 skin test-reacting cattle, of which 131 were confirmed as tuberculous, and in 128 cattle from TB-free herds. For the skin test reactors, there was a positive correlation between the IFN-gamma responses to PPD from Mycobacterium bovis (PPDB) and PPD from Mycobacterium avium (PPDA), indicating cross-reactivity between these complex antigens which are the basis of the skin test. In comparisons of the ESAT-6 IFN-gamma test with a PPD IFN-gamma test (using PPDB compared with PPDA), there was a decrease in sensitivity (76.3 per cent vs 89.3 per cent), but a clear increase in specificity (99.2 per cent vs 92.2 per cent). The provision of high specificity, even with lower sensitivity, offers major benefits for testing in areas with a low incidence of TB.  相似文献   

Phylogenetic, antigenic and clinical characterization of type 2 BVDV from North America   总被引：1，自引：0，他引：1  

Ridpath JF  Neill JD  Frey M  Landgraf JG 《Veterinary microbiology》2000,77(1-2):145-155

Bovine viral diarrhea virus (BVDV) infection continues to have a significant impact upon US cattle producers despite the availability of more than 140 federally licensed vaccines. Detection and control is hampered by viral heterogeneity that results in differences in neutralizing epitopes, cytopathology and virulence. Recently it was found that there are two different genotypes, BVDV1 and BVDV2, among BVDV. BVDV2 isolates make up a significant proportion of the BVDV isolated in North America. Serologically BVDV2 viruses can be distinguished from BVDV1 and border disease viruses. Mab binding also distinguishes between BVDV1, BVDV2 and BDV. Like the BVDV1 viruses, BVDV2 viruses may exist as one of two biotypes, cytopathic or noncytopathic, based on their activity in cultured cells. Cytopathogenic effects on cultured cells does not correlate with virulence in vivo, as BVDV2 associated with hemorrhagic syndrome (HS) are noncytopathic. Variation among BVDV1 and BVDV2 in the 5' UTR is similar. Phylogenetic analysis and differences in virulence suggest that BVDV2 are heterogeneous. Symptoms resulting from BVDV2 infections may range from clinically inapparent to clinically severe. Recently, disease outbreaks associated with acute uncomplicated BVDV infection have been reported in the US and Canada. These outbreaks of clinically severe disease, termed HS, were all associated with viruses from the BVDV2 genotype. Not all BVDV2 isolates cause clinically severe disease. Avirulent BVDV2 isolates do exist and may predominate over virulent BVDV2 in nature. When virulent BVDV2 viruses are inoculated into calves they induce a disease characterized by fever, diarrhea, leukopenia, lymphopenia, neutropenia, thrombocytopenia, and death. Infection with avirulent BVDV2 results in a reduction of luekocytes that may be accompanied by a low-grade fever. These viruses do not cause clinical disease or a clinical leukopenia.  相似文献   

Hyperthermia and Delayed-Onset Myopathy after Recovery from Anesthesia in a Horse   总被引：1，自引：0，他引：1  

Nicola Grint BVSc  DVA  DiplECVA  MRCVS  Dylan Gorvy BSc  BVSc  PhD  CertES  MRCVS  Alexandra Dugdale MA  VetMB  DVA  DiplECVA  MRCVS 《Journal of Equine Veterinary Science》2007,27(5):221-227

A 13-year old Thoroughbred cross gelding (528 kg) underwent lameness investigation. Because of his temperament, general anesthesia was required to facilitate ultrasound of the left fore fetlock and intra-articular medication of three joints. Anesthesia was induced with ketamine/diazepam after acepromazine/detomidine premedication. Anesthesia was maintained for 40 minutes with a guaifenesin/detomidine/ketamine intravenous infusion. Recovery from anesthesia was initially uneventful, although of a moderate duration (70 minutes). Once standing, the horse proceeded to box walk in an agitated state and became recumbent on two occasions. The horse was manually restrained, at which time its rectal temperature was 41.8°C. Cooling measures were employed (fans, ice-water enemas, wet rugs, intravenous fluid therapy (IVFT), and topical application of surgical spirit) until rectal temperature reached 38.7°C. IVFT was continued for a further 16 hours. Four days after recovery from anesthesia, bilateral triceps, deltoideus, trapezius, and rhomboideus muscle swelling was observed. Blood creatinine kinase was elevated (24,898 IU/L). Treatment for postanesthetic myopathy was initiated (hot packing of the muscle groups, topical dimethylsulfoxide [DMSO] cream application, and oral phenylbutazone). Myoglobinuria was not observed at any time. Muscle swelling decreased over the following 3 days. The horse was discharged on day 11 and has since returned to work.  相似文献   

Excretion of Leptospira interrogans serovar hardjo following calving or abortion     

W A Ellis  J J O'Brien  J A Cassells  S D Neill  J Hanna 《Research in veterinary science》1985,39(3):296-298

Leptospira interrogans serovar hardjo was demonstrated in the vaginal discharges of 12 experimentally infected heifers for up to eight days after abortion or calving. Organisms were recovered from the oviducts of heifers examined at slaughter eight to 22 days after calving or 32 to 91 days after infection. They were also recovered from the uteri of four heifers eight to 22 days after calving.  相似文献   

Light availability influences root carbohydrates, and potentially vigor, in white oak advance regeneration     

Dylan N. Dillaway  Jeffrey W. Stringer  Lynne K. Rieske 《Forest Ecology and Management》2007,250(3):227-233

Oaks (Quercus spp.) are experiencing recurring regeneration failures associated with pervasive mid- and under-story strata of shade tolerant species in intact, undisturbed forests. Where oak regeneration occurs, inadequate vertical height and depleted root carbohydrate stores impede the ability of regenerating oaks to respond when light does become available. A variety of silvicultural techniques have been developed to increase the penetration of diffuse light, enhancing the light environment on the forest floor, and thereby increasing the likelihood of regenerating oaks to successfully respond to increased light transmittance. We measured shoot and root characteristics, and root soluble non-structural carbohydrate concentrations of white oak (Q. alba L.) advance regeneration exposed to enhanced light intensities associated with a mid-story removal and a clearcut, and compared white oak regeneration vigor to untreated controls.

Root diameter and soluble non-structural carbohydrates increased with increasing light availability. Our data suggest that white oak responds to increases in light transmittance by building below-ground biomass and carbohydrates in the root system prior to an above-ground response. Our study shows that white oak regeneration vigor increases with only modest increases in light. In the absence of other pressures, enhancing the light environment to the forest floor should contribute to successful regeneration of this species.  相似文献   

Bovine congenital erythropoietic protoporphyria in a crossbred limousin heifer in Ireland     

Conor G. McAloon  Michael L. Doherty  Henry O’Neill  Michael Badminton  Eoin G. Ryan 《Irish veterinary journal》2015,68(1)

An unusual case of an 11-month-old, black Limousin-cross heifer, with an 8-month history of episodic seizures and photosensitisation, was referred by a veterinary practitioner to the Farm Animal Section of the UCD Veterinary Hospital, School of Veterinary Medicine, University College Dublin, Ireland, in August 2014. Following an investigation, a diagnosis of Bovine Congenital Erythropoietic Protoporphyria (BCEPP) was made. To the authors’ knowledge this is the first report of such a case in Ireland. BCEPP should be considered as a differential diagnosis in young animals displaying periodic seizures and/or photosensitisation.

Electronic supplementary material

The online version of this article (doi:10.1186/s13620-015-0044-3) contains supplementary material, which is available to authorized users.  相似文献   

A systematic review and meta-analysis of factors associated with anthelmintic resistance in sheep     

L.C. Falzon  T.J. O’Neill  P.I. Menzies  A.S. Peregrine  A. Jones-Bitton  J. vanLeeuwen  A. Mederos 《Preventive veterinary medicine》2014

Background

Anthelmintic drugs have been widely used in sheep as a cost-effective means for gastro-intestinal nematode (GIN) control. However, growing anthelmintic resistance (AHR) has created a compelling need to identify evidence-based management recommendations that reduce the risk of further development and impact of AHR.

Objective

To identify, critically assess, and synthesize available data from primary research on factors associated with AHR in sheep.

Methods

Publications reporting original observational or experimental research on selected factors associated with AHR in sheep GINs and published after 1974, were identified through two processes. Three electronic databases (PubMed, Agricola, CAB) and Web of Science (a collection of databases) were searched for potentially relevant publications. Additional publications were identified through consultation with experts, manual search of references of included publications and conference proceedings, and information solicited from small ruminant practitioner list-serves. Two independent investigators screened abstracts for relevance. Relevant publications were assessed for risk of systematic bias. Where sufficient data were available, random-effects Meta-Analyses (MAs) were performed to estimate the pooled Odds Ratio (OR) and 95% Confidence Intervals (CIs) of AHR for factors reported in ≥2 publications.

Results

Of the 1712 abstracts screened for eligibility, 131 were deemed relevant for full publication review. Thirty publications describing 25 individual studies (15 observational studies, 7 challenge trials, and 3 controlled trials) were included in the qualitative synthesis and assessed for systematic bias. Unclear (i.e. not reported, or unable to assess) or high risk of selection bias and confounding bias was found in 93% (14/15) and 60% (9/15) of the observational studies, respectively, while unclear risk of selection bias was identified in all of the trials. Ten independent studies were included in the quantitative synthesis, and MAs were performed for five factors. Only high frequency of treatment was a significant risk factor (OR = 4.39; 95% CI = 1.59, 12.14), while the remaining 4 variables were marginally significant: mixed-species grazing (OR = 1.63; 95% CI = 0.66, 4.07); flock size (OR = 1.02; 95% CI = 0.97, 1.07); use of long-acting drug formulations (OR = 2.85; 95% CI = 0.79, 10.24); and drench-and-shift pasture management (OR = 4.08; 95% CI = 0.75, 22.16).

Conclusions

While there is abundant literature on the topic of AHR in sheep GINs, few studies have explicitly investigated the association between putative risk or protective factors and AHR. Consequently, several of the current recommendations on parasite management are not evidence-based. Moreover, many of the studies included in this review had a high or unclear risk of systematic bias, highlighting the need to improve study design and/or reporting of future research carried out in this field.  相似文献   

A preliminary study on the effects of dietary supplementation of brewers yeast and nucleotides, singularly or in combination, on juvenile red drum (Sciaenops ocellatus)     

Peng Li  Gary S Burr  Jonathan Goff  Kasey W Whiteman  Kenneth B Davis  Robert R Vega  William H Neill  & Delbert M Gatlin III 《Aquaculture Research》2005,36(11):1120-1127

This study was designed to evaluate the effects of dietary supplementation with brewers yeast (Brewtech^®) and nucleotides (Optimûn), either singularly or in combination, on red drum growth, body composition, stress responses and possible resistance to Amyloodinium ocellatum infection. Juvenile red drum (～1 g initially) fed practical fish‐meal‐based diets for 6 weeks had similar weight gain regardless of whether the diet was unsupplemented (basal) or supplemented with brewers yeast (2% of diet), nucleotides (Optimûn at 0.2% of diet) or both brewers yeast (2% of diet) and nucleotides (Optimûn at 0.2% of diet). Dietary effects on hepatosomatic index, intraperitoneal fat ratio or whole‐body composition were not significant, except that fish fed the singular nucleotide supplement had a significantly higher whole‐body lipid content compared with fish fed the basal diet. No significant dietary effects on cortisol response were observed after a 15 min confinement stress test perhaps because of the extreme variation among individual fish. Subsequently, in situ challenge by co‐habitation with A. ocellatum caused 100% mortality regardless of dietary treatment within a 48 h period. It is concluded that dietary supplementation of brewers yeast and nucleotides did not promote enhanced growth or improved cortisol response and resistance to uncontrolled amyloodiniosis in juvenile red drum, at least at the tested dosages.  相似文献