Projections regarding employment: the future impact of automation on workers     

Farber HS 《Science (New York, N.Y.)》1986,232(4753):1022-1023

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Introduction to practice management software          下载免费PDF全文

Farber PL 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(11):905-910

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Modelling forest regeneration processes in clear-cut and burned areas in the Angara Region     

V. Sokolov  S. Farber  I. Danilin 《Water, air, and soil pollution》1995,82(1-2):155-160

A method to select measures for enhancing natural forest-regeneration process in areas under extensive management is discussed. Using available information on geomorphological site characteristics and stand parameters, indices are determined using a specific criterion that describes the forest regeneration process. Using these indices as model inputs, clearcuts and burns can be classified; within each stratum the natural forest regeneration process is similar. Analysing these strata, one can select a regime of forest treatment that is appropriate for a given stratum and, consequently, for the clearcuts (or burns) it includes.  相似文献   

Identification of presynaptic neurons by laser photostimulation   总被引：1，自引：0，他引：1  

I C Farber  A Grinvald 《Science (New York, N.Y.)》1983,222(4627):1025-1027

An optical method involving the use of a laser and a novel fluorescent dye as a photostimulation probe has been developed to identify presynaptic neurons in a large ensemble of cells. Illumination of an extracellularly stained neuron by the laser microbeam evokes action potentials. With this technique an interneuron connecting identified leech neurons was quickly located. The method speeds up the elucidation of neuronal networks, especially when small cells are involved.  相似文献   

Reformation of functional liver polyribosomes from ribosome monomers in the absence of RNA synthesis   总被引：2，自引：0，他引：2  

G A Stewart  E Farber 《Science (New York, N.Y.)》1967,157(784):67-69

The administration to rats of the ethyl analog of methionine, ethionine, results in the rapid decrease in the hepatic concentration of adenosine triphosphate followed by an extensive disaggregation of polysomes to ribosome monomers and a concomitant inhibition of protein synthesis. These effects are readily reversed by the injection of methionine or precursors of adenine nucleotides such as adenine. The reformation of liver polyribosomes in such animals following the administration of adenine plus methionine was found to occur under conditions in which new RNA synthesis was markedly inhibited. Free messenger RNA without attached ribosomes must be capable of remaining functionally active in the liver cytoplasm for many hours.  相似文献   

Chemical carcinogenesis: persistence of bound forms of 2-fluorenylacetamide   总被引：3，自引：0，他引：3  

S M Epstein  J McNary  B Bartus  E Farber 《Science (New York, N.Y.)》1968,162(856):907-908

The persistent binding of metabolites of hepatic carcinogen, 2-fluorenylacetamide, to glycogen and to DNA in a new population of liver cells, hyperplastic nodules, and to glycogen in liver cancer cells weeks to months after the carcinogen was removed from the animals' diet is indicated by spectrophotometric, chromatographic, and mass spectrographic data. This persistence of binding does not appear to occur in the nonhyperplastic or nonneoplastic liver surrounding the nodules or the cancer.  相似文献   

Phonon dispersions of fcc delta-plutonium-gallium by inelastic x-ray scattering     

Wong J  Krisch M  Farber DL  Occelli F  Schwartz AJ  Chiang TC  Wall M  Boro C  Xu R 《Science (New York, N.Y.)》2003,301(5636):1078-1080

We report an experimental determination of the phonon dispersion curves in a face-centered cubic (fcc) delta-plutonium-0.6 weight % gallium alloy. Several unusual features, including a large elastic anisotropy, a small-shear elastic modulus C', a Kohn-like anomaly in the T1[011] branch, and a pronounced softening of the [111] transverse modes, are found. These features can be related to the phase transitions of plutonium and to strong coupling between the lattice structure and the 5f valence instabilities. Our results also provide a critical test for theoretical treatments of highly correlated 5f electron systems as exemplified by recent dynamical mean field theory calculations for delta-plutonium.  相似文献   

Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of the C3H mouse retina   总被引：17，自引：0，他引：17  

D B Farber  R N Lolley 《Science (New York, N.Y.)》1974,186(4162):449-451

As a result of an early deficiency in cyclic nucleotide phosphodiesterase activity, guanosine 3',5'-monophosphate accumulates in retinal photoreceptor cells before they begin to degenerate. It is suggested that degeneration of the photoreceptor cells is related to an imbalance in their metabolism or function which is caused by the elevated levels of cyclic guanosine monophosphate.  相似文献   

Newsgathering     

Hirschberg E  Joseph Fu SC  Frisell WR  Farber E  Potter VR  Rusch HP  Saffiotti U  Shimkin MB  Brennan MJ  Nowell PC  Creech HJ  Taylor RM  Schabel FM  Frei E  Lepage GA  Weinhouse S  Hall TC 《Science (New York, N.Y.)》1972,176(4041):1288-1289

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Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria     

Sonnenberg GF  Monticelli LA  Alenghat T  Fung TC  Hutnick NA  Kunisawa J  Shibata N  Grunberg S  Sinha R  Zahm AM  Tardif MR  Sathaliyawala T  Kubota M  Farber DL  Collman RG  Shaked A  Fouser LA  Weiner DB  Tessier PA  Friedman JR  Kiyono H  Bushman FD  Chang KM  Artis D 《Science (New York, N.Y.)》2012,336(6086):1321-1325

The mammalian intestinal tract is colonized by trillions of beneficial commensal bacteria that are anatomically restricted to specific niches. However, the mechanisms that regulate anatomical containment remain unclear. Here, we show that interleukin-22 (IL-22)-producing innate lymphoid cells (ILCs) are present in intestinal tissues of healthy mammals. Depletion of ILCs resulted in peripheral dissemination of commensal bacteria and systemic inflammation, which was prevented by administration of IL-22. Disseminating bacteria were identified as Alcaligenes species originating from host lymphoid tissues. Alcaligenes was sufficient to promote systemic inflammation after ILC depletion in mice, and Alcaligenes-specific systemic immune responses were associated with Crohn's disease and progressive hepatitis C virus infection in patients. Collectively, these data indicate that ILCs regulate selective containment of lymphoid-resident bacteria to prevent systemic inflammation associated with chronic diseases.  相似文献