The ACVD task force on canine atopic dermatitis (VI): IgE-induced immediate and late-phase reactions, two inflammatory sequences at sites of intradermal allergen injections.     

P B Hill  A Hillier  T Olivry 《Veterinary immunology and immunopathology》2001,81(3-4):199-204

Intradermal testing is a common diagnostic procedure used in the evaluation of dogs with suspected atopic dermatitis (AD). To do this, most investigators assess the appearance of wheals that develop at the sites of intradermal allergen injections. However, wheals are rarely seen in dogs with naturally occurring AD. Furthermore, infiltration of inflammatory cells into the injection sites can occur 6-24h later, a phenomenon known as the late-phase reaction. The histological appearance of these late-phase reactions closely approximates that seen in the natural disease, suggesting that they might be more relevant than the immediate reactions. In this paper, we review the literature on immediate and late-phase reactions and re-assess the evidence for using current intradermal testing procedures as a diagnostic test in dogs.  相似文献   

Effect of a one-off sporidesmin challenge on the milk production of dairy cows     

ZM Matthews  MG Collett  JC Marshall  AC Partridge  PJ Derrick  PJB Edwards 《New Zealand veterinary journal》2018,66(5):261-266

  相似文献   

Greenhouse gas mitigation potential of agricultural land in Great Britain     

N. Fitton  C. P. Ejerenwa  A. Bhogal  P. Edgington  H. Black  A. Lilly  D. Barraclough  F. Worrall  J. Hillier  P. Smith 《Soil Use and Management》2011,27(4):491-501

The aim of this paper is to assess the greenhouse gas (GHG) mitigation potential of croplands and grasslands in Great Britain under different management practices. We consider the feasible land management options for grass and cropland using county level land‐use data with estimates of per‐area mitigation potential for individual and total GHGs, to identify the land management options with the greatest cost‐effective mitigation potential. We show that for grasslands, uncertainties still remain on the mitigation potential because of their climatic sensitivity and also their less intensive management. For croplands in Great Britain, the technical mean GHG mitigation potentials for all cropland management practices range from 17 Mt CO₂‐eq. per 20 yr to 39 Mt CO₂‐eq. per 20 yr. There are significant regional variation in all cases, with the greatest potentials in England, negligible potential in Wales and intermediate potential in Scotland, with country differences largely driven by the areas of cropland and grassland in each country. Practices such as agronomic improvement and nutrient management are the most promising options because of their impact on N₂O emissions and also their larger potential at low cost. In terms of annual emissions from agriculture, calculated mitigation potentials are small, where the technical mitigation potential of agronomy and nutrient management strategies are ca. 4.5 and 3.8%, respectively (agricultural emissions account for ca. 9% or 47.7 Mt CO₂‐eq., of total Great Britain GHG emissions, Department of Energy and Climate Change, UK). However when compared with the land use, land‐use change and forestry sector (LULUCF) emissions, nutrient management would reduce further emission reductions by approximately half of the 2005 LULUCF sink (i.e. ?1.6 Mt CO₂‐eq. per year).  相似文献   

Pulsed-field gel electrophoresis patterns and antimicrobial susceptibility phenotypes for coagulase-positive staphylococcal isolates from pustules and carriage sites in dogs with superficial bacterial folliculitis     

Pinchbeck LR  Cole LK  Hillier A  Kowalski JJ  Rajala-Schultz PJ  Bannerman TL  York S 《American journal of veterinary research》2007,68(5):535-542

OBJECTIVE: To determine whether coagulase-positive staphylococcal isolates that are genotypically the same strain obtained from pustules and carriage sites of individual dogs with superficial bacterial folliculitis have the same antimicrobial susceptibility phenotype. ANIMALS: 40 dogs with superficial bacterial folliculitis. PROCEDURES: Samples were obtained from 3 pustules and 3 carriage sites (ie, anus, nonlesional axillary skin, and nasal mucosa) for bacterial culture, morphologic identification, Gram staining, catalase and coagulase testing, antimicrobial susceptibility testing, speciation, and pulsed-field gel electrophoresis (PFGE). RESULTS: 223 isolates from pustules and carriage sites were included. Seventeen susceptibility phenotypes were found among isolates. One hundred twenty-eight (100%) isolates from pustules and 95 (100%) isolates from carriage sites were susceptible to cephalothin; 128 (100%) isolates from pustules and 94 (98.9%) isolates from carriage sites were susceptible to amoxicillin-clavulanic acid; 114 (89.1%) isolates from pustules and 82 (86.3%) isolates from carriage sites were susceptible to erythromycin and lincomycin hydrochloride; and 103 (80.5%) isolates from pustules and 70 (73.7%) isolates from carriage sites were susceptible to trimethoprim-sulfamethoxazole. In 37 of 39 (94.9%) dogs, isolates with the same PFGE pattern from multiple pustules had the same susceptibility phenotype. In 21 of 33 (63.6%) dogs, isolates from multiple carriage sites with the same PFGE pattern had the same susceptibility phenotype. CONCLUSIONS AND CLINICAL RELEVANCE: In dogs with superficial bacterial folliculitis, most coagulase-positive staphylococcal isolates from pustules that are genotypically the same strain will have the same susceptibility phenotype and treatment may be based on empiric antimicrobial selection or susceptibility testing of 1 lesional isolate.  相似文献   

Effect of hydroponically produced oat grass on ration digestibility of cattle     

R J Hillier  T W Perry 《Journal of animal science》1969,29(5):783-785

  相似文献   

Evaluation of an ear cleanser for the treatment of infectious otitis externa in dogs     

Cole LK  Kwochka KW  Kowalski JJ  Hillier A  Hoshaw-Woodard SL 《Veterinary therapeutics : research in applied veterinary medicine》2003,4(1):12-23

Thirty-one ears (16 dogs) with otitis externa originating from bacterial or yeast infections were enrolled in a study to evaluate the in vivo efficacy of an ear cleanser containing 2.5% lactic acid and 0.1% salicylic acid for the treatment of infectious otitis externa. The affected ears were treated with the ear cleanser twice daily for 2 weeks and evaluated after 1 and 2 weeks of treatment. The ear cleanser was effective in resolution of infection in 67.7% of the ears, and clinical signs of infectious otitis externa were significantly reduced within 2 weeks.  相似文献   

Comparison of pulse administration versus once daily administration of itraconazole for the treatment of Malassezia pachydermatis dermatitis and otitis in dogs     

Pinchbeck LR  Hillier A  Kowalski JJ  Kwochka KW 《Journal of the American Veterinary Medical Association》2002,220(12):1807-1812

OBJECTIVE To compare clinical efficacy of pulse administration with itraconazole versus once daily administration for the treatment of cutaneous and otic M pachydermatis infection in dogs. DESIGN: Randomized controlled trial. ANIMALS: 20 dogs. PROCEDURE: Dogs were treated with itraconazole orally (n = 10/group), using a pulse administration regimen (5 mg/kg [2.3 mg/lb], PO, q 24 h for 2 consecutive days per week for 3 weeks) or once daily administration (5 mg/kg, PO, q 24 h for 21 days). No other treatment was permitted. On days 0 and 21, clinical severity of cutaneous and otic disease was assessed, and samples were collected for cytologic examination and yeast culture. Cytology (sum of the mean number of yeast organisms per oil immersion field for affected sites) and culture (mean of the score for extent of yeast growth for samples from affected sites) scores were calculated. RESULTS: For dogs in both treatment groups, clinical severity of cutaneous and otic disease was significantly decreased by day 21, but decrease in severity was not significantly different between groups. Similarly, skin cytology, skin culture, and ear culture scores were significantly decreased on day 21, compared with day 0, for both groups, but decreases were not significantly different between groups except that dogs in the pulse administration group had a significantly greater decrease in ear culture scores than did dogs in the daily administration group. However, when cytology scores only for ear samples were analyzed, day 21 score was not significantly decreased, compared with day 0 score, for either group. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that both pulse administration and once daily administration of itraconazole were efficacious in the treatment of M pachydermatis cutaneous infection in dogs. However, adjunctive treatment may be needed in dogs with M pachydermatis otitis.  相似文献   

Embryonic Loss in Sows with Repeated Propensity for Small Litter Size     

RD Geisert  S Sasakia  AC Clutter 《Reproduction in domestic animals》2007,42(3):333-335

Information is lacking as to the timing and cause of sows that repeatedly have low litter size over several parities. Sows evaluated for the present study had at least two parities either small or=12 (NL) litter size. Following breeding of sows with contemporary boars, reproductive tracts were obtained on day 30 of gestation. There was no difference (p > 0.10) between SL and NL sows in the number of CL, embryo weight or placental length. The total number of embryos and embryonic survival tended to be lower (p < 0.10) in SL sows compared with NL sows, but there were 5.1 less viable embryos (p < 0.03) in SL. Results indicate that time of conceptus loss in SL sows was variable throughout gestation.  相似文献   

评估调质时间和温度对猪颗粒饲料淀粉糊化度和维生素沉积的影响     

Lewis LL  Stark CR  Fahrenholz AC  Bergstrom JR  Jones CK 《广东饲料》2015,24(5)

本论文研究了饲料加工的两个关键参数(调质温度和时间)对育肥猪颗粒饲料淀粉糊化度和维生素沉积的影响。日粮配方为含30%干酒糟及其可溶物的玉米-豆粕型基础日粮。整个试验中配方保持不变。本试验采用2×3双因子设计,调质温度分别为77℃和88℃,调质时间分别15秒、30秒和60秒。此外,本试验还设置一个对照组,对照组饲料不采用调质制粒工艺,而是采用粉料饲喂。因此,本试验共有7个处理组。采集调质后制粒前(热干粉)、制粒后冷却前(热制粒)、以及制粒冷却后(冷制粒)的样品,并分析这三种样品的总淀粉率、淀粉糊化  相似文献   

Assessing the influence of mechanical ventilation on blood gases and blood pressure in rattlesnakes          下载免费PDF全文

Mads F Bertelsen  Rasmus Buchanan  Heidi M Jensen  Cleo AC Leite  Augusto S Abe  Søren S Nielsen  Tobias Wang 《Veterinary anaesthesia and analgesia》2015,42(4):386-393

ObjectiveTo characterize the impact of mechanical positive pressure ventilation on heart rate (HR), arterial blood pressure, blood gases, lactate, glucose, sodium, potassium and calcium concentrations in rattlesnakes during anesthesia and the subsequent recovery period.Study designProspective, randomized trial.AnimalsTwenty one fasted adult South American rattlesnakes (Crotalus durissus terrificus).MethodsSnakes were anesthetized with propofol (15 mg kg⁻¹) intravenously, endotracheally intubated and assigned to one of four ventilation regimens: Spontaneous ventilation, or mechanical ventilation at a tidal volume of 30 mL kg⁻¹ at 1 breath every 90 seconds, 5 breaths minute⁻¹, or 15 breaths minute⁻¹. Arterial blood was collected from indwelling catheters at 30, 40, and 60 minutes and 2, 6, and 24 hours following induction of anesthesia and analyzed for pH, PaO₂, PaCO₂, and selected variables. Mean arterial blood pressure (MAP) and HR were recorded at 30, 40, 60 minutes and 24 hours.ResultsSpontaneous ventilation and 1 breath every 90 seconds resulted in a mild hypercapnia (PaCO₂ 22.4 ± 4.3 mmHg [3.0 ± 0.6 kPa] and 24.5 ± 1.6 mmHg [3.3 ± 0.2 kPa], respectively), 5 breaths minute⁻¹ resulted in normocapnia (14.2 ± 2.7 mmHg [1.9 ± 0.4 kPa]), while 15 breaths minute⁻¹ caused marked hypocapnia (8.2 ± 2.5 mmHg [1.1 ± 0.3 kPa]). Following recovery, blood gases of the four groups were similar from 2 hours. Anesthesia, independent of ventilation was associated with significantly elevated glucose, lactate and potassium concentrations compared to values at 24 hours (p < 0.0001). MAP increased significantly with increasing ventilation frequency (p < 0.001). HR did not vary among regimens.Conclusions and clinical relevanceMechanical ventilation had a profound impact on blood gases and blood pressure. The results support the use of mechanical ventilation with a frequency of 1–2 breaths minute⁻¹ at a tidal volume of 30 mL kg⁻¹ during anesthesia in fasted snakes.  相似文献