Small Animal Clinical Diagnosis by Laboratory Methods.     

JN Mills 《Australian veterinary journal》2004,82(8):484-484

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The influence of mating management on fertility in ewes following progesterone-PMS treatment   总被引：2，自引：0，他引：2  

J J Jennings  J P Crowley 《The Veterinary record》1972,90(18):495-498

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Marine Pseudovibrio sp. as a Novel Source of Antimicrobials     

Susan P. Crowley  Fergal O’Gara  Orla O’Sullivan  Paul D. Cotter  Alan D. W. Dobson 《Marine drugs》2014,12(12):5916-5929

Antibiotic resistance among pathogenic microorganisms is becoming ever more common. Unfortunately, the development of new antibiotics which may combat resistance has decreased. Recently, however the oceans and the marine animals that reside there have received increased attention as a potential source for natural product discovery. Many marine eukaryotes interact and form close associations with microorganisms that inhabit their surfaces, many of which can inhibit the attachment, growth or survival of competitor species. It is the bioactive compounds responsible for the inhibition that is of interest to researchers on the hunt for novel bioactives. The genus Pseudovibrio has been repeatedly identified from the bacterial communities isolated from marine surfaces. In addition, antimicrobial activity assays have demonstrated significant antimicrobial producing capabilities throughout the genus. This review will describe the potency, spectrum and possible novelty of the compounds produced by these bacteria, while highlighting the capacity for this genus to produce natural antimicrobial compounds which could be employed to control undesirable bacteria in the healthcare and food production sectors.  相似文献   

Functional and structural responses of bacterial and fungal communities from paddy fields following long-term rice cultivation     

Yalong Liu  Ping Wang  Genxing Pan  David Crowley  Lianqing Li  Jinwei Zheng  Xuhui Zhang  Jufeng Zheng 《Journal of Soils and Sediments》2016,16(5):1460-1471

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Paleoclimatology: milankovitch and climate     

Crowley TJ 《Science (New York, N.Y.)》1985,227(4688):745-746

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Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold     

Wingren C  Crowley MP  Degano M  Chien Y  Wilson IA 《Science (New York, N.Y.)》2000,287(5451):310-314

Murine T10 and T22 are highly related nonclassical major histocompatibility complex (MHC) class Ib proteins that bind to certain gammadelta T cell receptors (TCRs) in the absence of other components. The crystal structure of T22b at 3.1 angstroms reveals similarities to MHC class I molecules, but one side of the normal peptide-binding groove is severely truncated, which allows direct access to the beta-sheet floor. Potential gammadelta TCR-binding sites can be inferred from functional mapping of T10 and T22 point mutants and allelic variants. Thus, T22 represents an unusual variant of the MHC-like fold and indicates that gammadelta and alphabeta TCRs interact differently with their respective MHC ligands.  相似文献   

Coeval large-scale magmatism in the Kalahari and Laurentian cratons during Rodinia assembly     

Hanson RE  Crowley JL  Bowring SA  Ramezani J  Gose WA  Dalziel IW  Pancake JA  Seidel EK  Blenkinsop TG  Mukwakwami J 《Science (New York, N.Y.)》2004,304(5674):1126-1129

We show that intraplate magmatism occurred 1106 to 1112 million years ago over an area of two million square kilometers within the Kalahari craton of southern Africa, during the same magnetic polarity chron as voluminous magmatism within the cratonic core of North America. These contemporaneous magmatic events occurred while the Rodinia supercontinent was being assembled and are inferred to be parts of a single large igneous province emplaced across the two cratons. Widespread intraplate magmatism during Rodinia assembly shows that mantle upwellings required to generate such provinces may occur independently of the supercontinent cycle.  相似文献   

A population of murine gammadelta T cells that recognize an inducible MHC class Ib molecule     

Crowley MP  Fahrer AM  Baumgarth N  Hampl J  Gutgemann I  Teyton L  Chien Y 《Science (New York, N.Y.)》2000,287(5451):314-316

Although gammadelta T cells are implicated in regulating immune responses, gammadelta T cell-ligand pairs that could mediate such regulatory functions have not been identified. Here, the expression of the major histocompatibility complex (MHC) class Ib T22 and the closely related T10 molecules is shown to be activation-induced, and they confer specificity to about 0.4% of the gammadelta T cells in normal mice. Thus, the increased expression of T22 and/or T10 might trigger immunoregulatory gammadelta T cells during immune responses. Furthermore, the fast on-rates and slow off-rates that characterize this receptor/ligand interaction would compensate for the low ligand stability and suggest a high threshold for gammadelta T cell activation.  相似文献   

Further controlled evaluations of fenbendazole as a bovine anthelmintic.     

J W Crowley  W J Foreyt  D H Bliss  A C Todd 《American journal of veterinary research》1977,38(5):689-692

The efficacy of fenbendazole (methyl-5-(phenythio)-2-benzimidazole-carbamate) in cattle parasitized by the lungworm Dictyocaulus viviparus and in other cattle parasitized by Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum was investigated in 3 controlled critical experiments. A single treatment with 5.0 mg/kg of body weight administered in the feed or in a 10% suspension exceeded 99% efficacy against these helminths. Dosages of 1, 0.5, 0.35, and 0.25 mg/kg of body weight administered for 5 days to individual calves in their feed were 99% efficacious against all helminths, except Haemonchus. The 1.0 mg/kg dose removed 99.5% of the Haemonchus, and the other 3 dosages had efficacies of 91.0, 93.7, and 95.6%, respectively. The small daily dosages were not evaluated against Dictyocaulus.  相似文献   

Some observations on the toxicity of hexachlorophane for sheep     

D M Pugh  J Crowley 《The Veterinary record》1966,78(3):86-91

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