Serum amyloid A protein (SAA) in horses: objective measurement of the acute phase response   总被引：1，自引：0，他引：1  

M B Pepys  M L Baltz  G A Tennent  J Kent  J Ousey  P D Rossdale 《Equine veterinary journal》1989,21(2):106-109

A sensitive and precise immunoassay for equine serum amyloid A protein (SAA) was established and used to determine, for the first time, the circulating concentration of this protein in health and disease. As in other species, equine SAA was present only at trace levels in healthy animals but behaved as an extremely sensitive and rapidly responding acute phase reactant following most forms of tissue injury, infection and inflammation, objectively reflecting the extent and activity of disease. Measurements of SAA should make a significant contribution to diagnosis and management of viral and bacterial infection in horses, and routine serial assays could provide an objective criterion for monitoring prospectively the general health of horses in training and racing.  相似文献   

Microsporidian encephalitis of farmed Atlantic salmon (Salmo salar) in British Columbia.          下载免费PDF全文

J R Brocklebank  D J Speare    M L Kent 《The Canadian veterinary journal. La revue veterinaire canadienne》1995,36(10):631-633

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Current therapies in exotic animal oncology.     

Jennifer E Graham  Michael S Kent  Alain Théon 《Veterinary Clinics of North America: Exotic Animal Practice》2004,7(3):757-81, vii

The majority of information on oncology therapies has been reported in humans, canine, and feline patients, and laboratory animals with experimentally induced tumors. A variety of treatments,including radiation therapy, chemotherapy, photodynamic therapy, and others have been used with exotic animals. There are many species of exotic pets, and anatomic differences, as well as husbandry and nutritional requirements, must be taken into account to provide optimal care. By providing a broad overview of therapies and considerations for treatment, this article is intended to provide the practitioner with an overview of approach and options when addressing oncology cases in exotic animals.  相似文献   

Another brick in the wall     

CR WILKS 《Australian veterinary journal》2004,82(12):762-762

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FEASIBILITY FOR USING HYPOFRACTIONATED STEREOTACTIC VOLUMETRIC MODULATED ARC RADIOTHERAPY (VMAT) WITH ADAPTIVE PLANNING FOR TREATMENT OF THYMOMA IN RABBITS: 15 CASES          下载免费PDF全文

Mario Dolera  Luca Malfassi  Giovanni Mazza  Gaetano Urso  Massimo Sala  Silvia Marcarini  Nancy Carrara  Simone Pavesi  Sara Finesso  Michael S. Kent 《Veterinary radiology & ultrasound》2016,57(3):313-320

Thymoma is a relatively common tumor in rabbits. Treatment with surgery, radiation therapy, and chemotherapy alone or in combination has been reported with varying outcomes. Stereotactic volumetric modulated arc radiotherapy delivered in a hypofractionated manner allows high doses of radiation to be delivered to the target volume while allowing sparing of adjacent critical structures. This therapy is ideally suited for thymomas in rabbits given their size, the difficulty of multiple anesthesia episodes and the complexity of the radiotherapy plans required due to the tumor's proximity to the heart, lungs, and mediastinal structures. Fifteen rabbits with thymoma were prospectively recruited for this observational, single institution, single arm clinical study. All rabbits were imaged with both computed tomography (CT) and magnetic resonance imaging (MRI). A total dose of 40 Gy in six fractions was delivered using a single arc over an 11‐day period with repeat CT simulation done every other fraction for adaptive planning. Follow‐up evaluation was done through repeat CT and MRI imaging and revealed complete responses using the Response Evaluation Criteria in Solid Tumors (RECIST) criteria. Two rabbits had died at 618 and 718 days, 10 were alive and three were lost to follow‐up. Observed acute and late effects were graded according to the Veterinary Radiation Therapy Oncology Group (VRTOG) criteria and were found to be minimal.  相似文献   

Nalbuphine and butorphanol reverse opioid‐induced respiratory depression but increase arousal in etorphine‐immobilized goats (Capra hircus)          下载免费PDF全文

Anna J Haw  Leith CR Meyer  Andrea Fuller 《Veterinary anaesthesia and analgesia》2016,43(5):539-548

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Alphaviruses: current biology. , Edited by S Mahalingam,LJ Herrero and BL Herring. Caister Academic Press,Norfolk, UK. 183 pages. Price US$319.00 ISBN 978‐1‐910190‐15‐9.          下载免费PDF全文

CR Wilks 《Australian veterinary journal》2016,94(3):59-59

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Never mind the length,feel the quality          下载免费PDF全文

M. S. Kent 《The Journal of small animal practice》2016,57(11):579-579

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Characterization of protection against systemic infection and disease from experimental bovine viral diarrhea virus type 2 infection by use of a modified-live noncytopathic type 1 vaccine in calves     

Kelling CL  Hunsaker BD  Steffen DJ  Topliff CL  Eskridge KM 《American journal of veterinary research》2007,68(7):788-796

OBJECTIVE: To evaluate protection resulting from use of a modified-live noncytopathic bovine viral diarrhea virus (BVDV) type 1 vaccine against systemic infection and clinical disease in calves challenged with type 2 BVDV. ANIMALS: 10 calves, 5 to 7 months of age. PROCEDURES: Calves were allocated (n = 5/group) to be nonvaccinated or vaccinated SC on day 0 with BVDV 1 (WRL strain). Calves in both groups were challenged intranasally with BVDV type 2 isolate 890 on day 21. Rectal temperatures and clinical signs of disease were recorded daily, and total and differential WBC and platelet counts were performed. Histologic examinations and immunohistochemical analyses to detect lesions and distribution of viral antigens, respectively, were performed. RESULTS: After challenge exposure to BVDV type 2, nonvaccinated calves developed high rectal temperatures, increased respiratory rates, viremia, leukopenia, lymphopenia, and infection of the thymus. Vaccinated calves did not develop high rectal temperatures or clinical signs of respiratory tract disease. Vaccinated calves appeared to be protected against systemic replication of virus in that they did not develop leukopenia, lymphopenia, viremia, or infection of target organs, and infectious virus was not detected in peripheral blood mononuclear cells or the thymus. CONCLUSIONS AND CLINICAL RELEVANCE: The modified-live BVDV type 1 vaccine protected against systemic infection and disease after experimental challenge exposure with BVDV type 2. The vaccine protected calves against infection and viremia and prevented infection of target lymphoid cells.  相似文献   

Effects of a single subcutaneous dose of enoxaparin on veterinary viscoelastic coagulation monitor variables in healthy cats: Double blind,placebo controlled cross-over trial     

Ivayla D. Yozova  Michael S. Kent  Karl E. Jandrey 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(1):133-139

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