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Thaliblastine exhibits dose dependent cytotoxic effect on HL-60, HL-60/DOX, RHE and HD-MY-2 leukemia cells. Additionally, typical for apoptosis oligonucleosomal DNA fragmentation could be detected in leukemia cells treated with thaliblastine. Moreover, an MDR-phenotype reversing effect of thaliblastine was also identified. 相似文献
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ILIYA Ralchev MARIN Todorov 《黑龙江农业科学》2006,(5):93-95
研究目标是通过在非繁殖季节和繁殖季节的发情周期内利用腹腔镜研究生殖器官的宏观形态.经研究认为它们的科学和实践价值在于可以根据它们反馈的真实信息判定发情周期和受精的最佳时间.该研究只是通过自然观察而没有考虑生殖器官形态和功能的复杂关系,所以只是对母羊生殖系统变化规律的部分观点.研究结果为腹腔镜在不同生殖阶段繁殖器官形态变化的动态研究中的潜在作用提供了证据支持. 相似文献
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MARIN Todorov 《黑龙江农业科学》2006,(5):96-97,103
比较在保加利亚山地条件下,利木赞牛、塞勒斯牛、赫里福德牛和安格斯牛的牛肉产品在数量和质量上的区别.在牛肉产量上,利木赞牛犊牛和其他品种相比有最高的价值和很大的不同,它们的肉脂肪含量很少.安格斯犊牛的骨骼比例最少,其次是赫里福德犊牛和利木赞犊牛,塞勒斯犊牛的骨骼百分比最高.研究表明,根据新的欧盟市场前景和在屠宰后犊牛胴体质量和数量方面的最新需求,保加利亚肉牛饲养需要更高效的品种(如利木赞)及其杂交品种,这样才会为保加利亚牧场主带来更多的利润. 相似文献
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J. Todorov T. Todorova U. Zimmermann W.M. Arnold C. Leiding R. Hahn J. Hahn 《Reproduction in domestic animals》1992,27(5):307-309
Am 27.8.1992 wurde beim Besamungsverein Neustadt (BVN) in Neustadt a.d. Aisch ein geklontes Fleckviehkalb geboren. Die Identität der Abstammung konnte eindeutig gesichert werden. Der erfolgreiche Kerntransfer in einem Versuchsprogramm soll belegen, daβ sich nach der Fusion einer Blastomere aus einem Spenderembryo mit einer in vitro gereiften und enukleierten Empfängeroozyte ein Embryo entwickeln kann, der nach Transfer auf ein Empfängertier zur Geburt eines gesunden Kalbes führt.
Contents: A cloned calf was born in Neustadt ad. Aisch
A cloned "Fleckvieh" calf was born at the Al-Association Neustadt (BVN) in Neustadt a.d. Aisch on August, 27, 1992. The identity of the parentage could be verified undoubtedly. The successful nuclear transfer in an experimental program showed that the fusion of a blastomere from a donor embryo with an in vitro matured and enucleated recipient oocyte led to the development of an embryo, and after transfer to a synchronous recipient to the birth of a healthy calf. 相似文献
Contents: A cloned calf was born in Neustadt ad. Aisch
A cloned "Fleckvieh" calf was born at the Al-Association Neustadt (BVN) in Neustadt a.d. Aisch on August, 27, 1992. The identity of the parentage could be verified undoubtedly. The successful nuclear transfer in an experimental program showed that the fusion of a blastomere from a donor embryo with an in vitro matured and enucleated recipient oocyte led to the development of an embryo, and after transfer to a synchronous recipient to the birth of a healthy calf. 相似文献
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Inferences of competence from faces predict election outcomes 总被引：1，自引：0，他引：1
We show that inferences of competence based solely on facial appearance predicted the outcomes of U.S. congressional elections better than chance (e.g., 68.8% of the Senate races in 2004) and also were linearly related to the margin of victory. These inferences were specific to competence and occurred within a 1-second exposure to the faces of the candidates. The findings suggest that rapid, unreflective trait inferences can contribute to voting choices, which are widely assumed to be based primarily on rational and deliberative considerations. 相似文献
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par J.L. PEREZ MARIN 《EPPO Bulletin》1982,12(2):81-85
Dans la zone du Rioja et dans la plupart des autres régions viticoles de l'Espagne, le problème de la lutte chimique contre la pourriture grise des raisins n'est pas encore résolu, en raison de la variabilité et de la fréquente médiocrité des produits utilisés. Ceux-ci comprennent la dichlofluanide, les benzimidazoles et les imides cycliques, dont l'efficacité dans le meilleur des cas ne dépasse pas 60 %. Par ailleurs, les résultats obtenus au cours des deux dernières années laissent penser à l'apparition de souches de Botrytis cinerea résistantes à ces produits. Bien que le nombre de traitements dépende surtout des conditions climatiques, on effectue en général deux traitements; le premier à la véraison, et le second trois semaines avant la récolte. Dans les vignobles très sensibles, une application supplémental est faite au moment de la chute des capuchons floraux. Sur le cépage Grenache, il faut même deux traitements en plus, pendant la floraison et à la chute des capuchons floraux. Les examens révèlent que les produits susmentionnés n'affectent, ni la fermentation, ni le goût des vins, si le dernier traitement est appliqué trois semaines avant la récolte. 相似文献
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LILIANA M. MARIN JAMIE BROWN CHAS McBRIEN RYAN BAUMWART VALERIE F. SAMII C. GUILLERMO COUTO 《Veterinary radiology & ultrasound》2007,48(4):332-334
The vertebral heart size (VHS) is used to objectively assess cardiac dimensions on thoracic radiographs. A high VHS suggest the presence of cardiac pathology, such as dilated cardiomyopathy, degenerative atrioventricular valvular disease, pericardial effusion, pericardioperitoneal diaphragmatic hernia, tricuspid dysplasia, ventricular septal defect, or patent ductus arteriosus, among others. However, breed or body conformation can influence the VHS. Because Greyhounds have a high prevalence of physiologic systolic murmurs associated with high aortic velocity, and large cardiac dimensions when compared with dogs of similar size, they are frequently suspected of having heart disease. The purpose of this study was to compare the VHS in normal Greyhounds with those in Rottweilers, and a group of dogs from various other breeds using both analog and digital radiology. The VHS was significantly higher in Greyhounds (P< 0.0001), when compared with Rottweilers and to other dog breeds. The mean VHS on lateral radiographs for Greyhounds was 10.5 +/- 0.1, for Rottweilers it was 9.8 +/- 0.1, and for mixed breed dogs it was 10.1 +/- 0.2. This study confirms that the relative cardiomegaly reported in necropsy and echocardiographic studies in Greyhounds is easily detected using plain radiography and the VHS. 相似文献
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Development of monoclonal antibodies to PK'X', the causative agent of proliferative kidney disease 总被引：1，自引：0，他引：1
Abstract. Two monoclonal antibody probes were produced against PK'X' cells. The parasites were partially purified by filtration and centrifugation of kidney tissue from rainbow trout with proliferative kidney disease and used as antigen for immunization of mice. The resulting monoclonal antibodies reacted with PK'X' cell antigens in enzyme-linked immunosorbent assay and immunohistochemistry tests. One antibody (Mab 12) appeared to be specific for PK'X'in kidney tissue, while the other (Mab 18) cross-reacted with host cell antigens in the kidney tubules. These probes are invaluable tools for the investigation of parasite surface antigens and life cycle studies. 相似文献
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