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排序方式: 共有49条查询结果,搜索用时 15 毫秒
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Rosas-Ballina M Olofsson PS Ochani M Valdés-Ferrer SI Levine YA Reardon C Tusche MW Pavlov VA Andersson U Chavan S Mak TW Tracey KJ 《Science (New York, N.Y.)》2011,334(6052):98-101
Neural circuits regulate cytokine production to prevent potentially damaging inflammation. A prototypical vagus nerve circuit, the inflammatory reflex, inhibits tumor necrosis factor-α production in spleen by a mechanism requiring acetylcholine signaling through the α7 nicotinic acetylcholine receptor expressed on cytokine-producing macrophages. Nerve fibers in spleen lack the enzymatic machinery necessary for acetylcholine production; therefore, how does this neural circuit terminate in cholinergic signaling? We identified an acetylcholine-producing, memory phenotype T cell population in mice that is integral to the inflammatory reflex. These acetylcholine-producing T cells are required for inhibition of cytokine production by vagus nerve stimulation. Thus, action potentials originating in the vagus nerve regulate T cells, which in turn produce the neurotransmitter, acetylcholine, required to control innate immune responses. 相似文献
3.
Disease of geese caused by a new herpesvirus 总被引:3,自引:0,他引:3
PJ KETTERER BJ RODWELL HA WESTBURY† PT HOOPER† AR MACKENZIE‡ JG DINGLE§ HC PRIOR 《Australian veterinary journal》1990,67(12):446-448
A goose flock farmed outdoors in south-eastern Queensland suffered an outbreak of peracute disease with high death rate (97%). Small button ulcers and large plaques overlying lymphocyte aggregates were present on the mucosa of the small intestine of affected birds. Small white foci of necrosis and focal haemorrhages were seen in the livers. Numerous intranuclear inclusion bodies were observed microscopically in hepatocytes and a herpesvirus which grew rapidly in chicken kidney cells was isolated from tissues. Duck virus enteritis (DVE) was suspected but DVE antiserums failed to neutralise the virus. Further serological studies with a limited range of known avian herpesviruses have failed to identify the virus. Experimental transmission resulted in high mortality in geese (100%), lower mortality in ducklings and nil mortality in chickens. Surveillance studies showed no evidence of infection in domestic and wild birds beyond the original farm and the infection appears not to have been established in the area. Wild ducks, which were frequent visitors to the farm dam, were considered the most likely source of the infection. 相似文献
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P. Stefanoff M. Pfeffer W. Hellenbrand J. Rogalska F. Rühe A. Makówka J. Michalik B. Wodecka A. Rymaszewska D. Kiewra A. Baumann‐Popczyk G. Dobler 《Zoonoses and public health》2013,60(3):215-226
Tick‐borne encephalitis virus (TBEV) is the most important tick‐transmitted arbovirus causing human disease in Europe, but information on its endemic occurrence varies between countries because of differences in surveillance systems. Objective data are necessary to ascertain the disease risk for vaccination recommendations and other public health interventions. In two independent, separately planned projects, we used real‐time RT‐PCR to detect TBE virus in questing ticks. In Poland, 32 sampling sites were selected in 10 administrative districts located in regions where sporadic TBE cases were reported. In Germany, 18 sampling sites were selected in two districts located in a region with high TBE incidence. Altogether, >16 000 ticks were tested by real‐time RT‐PCR, with no sample testing positive for TBEV. A systematic search for published studies on TBEV prevalence in ticks in Poland and Germany also suggested that testing large numbers of collected ticks could not consistently assure virus detection in known endemic foci. Although assignment of results to administrative regions is essential for TBE risk mapping, this was possible in only 10 (investigating 22 417 ticks) of 15 published studies (>50 000 ticks) identified. We conclude that the collection and screening of ticks by real‐time RT‐PCR cannot be recommended for assessment of human TBE risk. Alternative methods of environmental TBEV monitoring should be considered, such as serological monitoring of rodents or other wildlife. 相似文献
7.
甘蓝型油菜(Brassica napus)无花瓣突变体“ Ap-Tengbe ”花瓣性状的遗传规律 总被引:2,自引:0,他引:2
本项研究旨在探明甘蓝型油菜突变体Ap-Tengbe无花瓣性状的遗传规律,‘Ap-Tengbe’和德国栽培品种‘Falcon’之间通过正反交产生两个方向的F1,BC1-1(F1和‘Ap-Tengebe’之间),BC1-2(F1和‘Falcon’之间)以及F2各遗传群体,根据田间各遗传群体PDgr(花瓣度)的观察和统计,作者提出‘Ap-Tenge’突变体无花瓣性状的遗传由细胞质和两对核隐性基因共同控制 相似文献
8.
Mak Chanratana Gwang Hyun Han Manoharan Melvin Joe Aritra Roy Choudhury Seshadri Sundaram Md. Abdul Halim 《Archives of Agronomy and Soil Science》2018,64(11):1489-1502
Methylobacterium oryzae CBMB20, a promising plant growth promoting bacteria (PGPB) and a biocontrol agent, was immobilized in different formulations such as wet chitosan, dry chitosan, wet alginate and dry alginate and were tested for tomato plant growth promotion. Chitosan solution (1.5%) with pH 5.5–6.0 and 90 min contact time was found optimal for immobilization. The chitosan formulations showed better entrapment efficiency and good degradability resistance apart from slow release of cells under prolonged incubation. Survivability of bacteria (80%) was observed in wet chitosan formulation even after 90 days of storage at 4°C. The spermosphere survival of bacteria was high in both dry and wet chitosan formulations applied soils even after 21 days under greenhouse conditions. While the alginate formulation degraded fully, partial degradation of chitosan formulation was observed even after 30 days, indicating its ability to support the survival of M. oryzae CBMB20 in soil. Plants inoculated with wet chitosan formulation registered 1.3 fold increase in the shoot and root length and dry weight compared to other treatments. Hence, chitosan formulation supporting better plant growth compared to alginate will be a better carrier for taking bacteria to the plant rhizosphere and thereby promote plant growth. 相似文献
9.
We present a 650-year Antarctic ice core record of concentration and isotopic ratios (δ(13)C and δ(18)O) of atmospheric carbon monoxide. Concentrations decreased by ~25% (14 parts per billion by volume) from the mid-1300s to the 1600s then recovered completely by the late 1800s. δ(13)C and δ(18)O decreased by about 2 and 4 per mil (‰), respectively, from the mid-1300s to the 1600s then increased by about 2.5 and 4‰ by the late 1800s. These observations and isotope mass balance model results imply that large variations in the degree of biomass burning in the Southern Hemisphere occurred during the last 650 years, with a decrease by about 50% in the 1600s, an increase of about 100% by the late 1800s, and another decrease by about 70% from the late 1800s to present day. 相似文献
10.
Tang Samuel C. N. Lo Irene M. C. Mak Mark S. H. 《Water, air, and soil pollution》2012,223(4):1713-1722
Two types of hydrogels with different functional groups, trimethylamine on quaternary ammonium and dimethylethoxyamine on
quaternary ammonium, were synthesized. Type 1 and type 2 hydrogels were characterized with Fourier transform infrared, X-ray
photoelectron spectroscopy and zeta potential analysis. The anion selectivity of these two hydrogels was investigated. The
surface charges of the type 2 hydrogel were lower than those of type 1, probably because of the presence of the hydroxyl group
in the ethoxy group. The Cr(VI) removal capacity of type 2 hydrogel was, therefore, less than that of type 1 hydrogel, although
their adsorption rates were similar. The anion selectivity of the hydrogels was found to have a similar order: Cr(VI) > sulphate
> bromide > As(V). Under the co-presence of Cr(VI) and sulphate conditions, type 2 hydrogel shows a higher selectivity towards
Cr(VI). The higher hydrophobicity was caused by the presence of the ethoxy group on the quaternary ammonium in type 2 hydrogel
and thus increased in selectivity towards monovalent ions (i.e. HCrO4−). In addition, the hydrogels have a high reusability. Compared with type 1 hydrogel, type 2 hydrogel has an advantage for
applications in Cr(VI) removal and recovery processes. 相似文献