Reviews section     

Dr Bill Symondson  W. O. C. Symondson  Dr Peter McEwen  Simon Oxley  Dr Patthumal Beevi  Houston Hobbs  Keith Harris  Dr R. T. Plumb  Professor P. G. Mantle  Professor J. Hemingway  Dr Barbara B. Shew  R. M. Baker  Professor P. A. Langley  David Dent 《Integrated Pest Management Reviews》1996,1(2):111-123

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Application and field validation of a PCR assay for the detection of Mycoplasma hyopneumoniae from swine lung tissue samples.   总被引：1，自引：0，他引：1  

Hugh Y Cai  Tony van Dreumel  Beverly McEwen  Geoff Hornby  Patricia Bell-Rogers  Pat McRaild  Gaylan Josephson  Grant Maxie 《Journal of veterinary diagnostic investigation》2007,19(1):91-95

A PCR assay was validated for the detection of Mycoplasma hyopneumoniae in porcine lung tissue. The detection limit of the assay was 0.18 colony-forming units/g of lung sample spiked with M. hyopneumoniae. In field validation, 426 pigs from 220 cases were examined for M. hyopneumoniae infection by M. hyopneumoniae PCR and a fluorescent antibody (FA) test. In total, 103 pig lungs (24.2%) were positive in the PCR test, and 69 pig lungs (16.2%) were positive in the FA test, among which, 62 pigs were positive for both PCR and FA test. Most of the PCR-positive but FA test-negative cases had lesions compatible with M. hyopneumoniae infection. With Bayesian modeling, the diagnostic sensitivity and specificity of the PCR were determined to be 97.3% and 93.0%, respectively.  相似文献   

Antimicrobial drug use and related management practices among Ontario swine producers          下载免费PDF全文

Dunlop RH  McEwen SA  Meek AH  Friendship RA  Clarke RC  Black WD 《The Canadian veterinary journal. La revue veterinaire canadienne》1998,39(2):87-96

A mail survey of swine producers in Ontario was undertaken during 1991 to describe the types, frequency, and motives for antimicrobial use. Two hundred operations that marketed fewer than 350 hogs per year, and 800 that marketed more than 350 per year were sent questionnaires, 63% of which were completed and returned. Most operations (86%) added antimicrobials to starter (weanling pig) rations, while fewer (29%) added these drugs to finisher pig rations. The most commonly used antimicrobials were tylosin, carbadox, and furazolidone in weanling pigs, and tylosin, lincomycin, and tetracycline in finishers. Water medication of grower-finisher pigs was practised on 25% of farms; 80% of farms had injected at least some grower-finisher pigs with antimicrobials in the 12 mo preceding the survey. Approximately 20% of operations that added antimicrobials to finisher rations did so for growth promotion purposes only, while others used them for disease treatment, prevention, control, or a combination of reasons. Among those not using antimicrobials in finisher rations, 83% did not believe they were necessary and 37% were concerned about the potential for residues in marketed hogs.  相似文献   

Associations among antimicrobial drug treatments and antimicrobial resistance of fecal Escherichia coli of swine on 34 farrow-to-finish farms in Ontario, Canada     

R.H Dunlop  S.A McEwen  A.H Meek  R.C Clarke  W.D Black  R.M Friendship 《Preventive veterinary medicine》1998,34(4):1610-305

Logistic regression was used to model associations between antimicrobial treatment and resistance among fecal Escherichia coli of finisher pigs at the farm level. Four sets of potential risk factors representing different levels of refinement of antimicrobial use on farms were modelled on resistance to antimicrobials. Final models for each antimicrobial were constructed from treatment and management variables significant on initial screening, and corrections for overdispersion were made. In general, in-feed antimicrobial treatment of pigs was more consistently associated with an increased risk of resistance than individual-animal treatment. Antimicrobial treatment in starter rations was significant in final models of resistance to ampicillin, carbadox, nitrofurantoin, sulfisoxizole, and tetracycline. Treatment in grower–finisher rations was significantly associated with resistance to ampicillin, spectinomycin, sulfisoxizole, and tetracycline. There was little evidence that in-feed antimicrobials increased the risk of resistance to gentamicin, which is a drug used only for individual-pig treatment in this study population. These results suggest that antimicrobial medication of rations of post-weaning pigs selects for and maintains antimicrobial resistance among E. coli of finisher pigs. Although resistance was common on farms that did not medicate rations of post-weaning pigs, the results indicate that antimicrobial use does increase the risk of resistance to the antimicrobials studied.  相似文献   

Comparative efficacy of crystalline and amorphous oxfendazole in sheep     

MJ CARRIGAN  P PILE  BF CHICK 《Australian veterinary journal》1990,67(5):195-196

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Syndromic surveillance using laboratory test requests: A practical guide informed by experience with two systems     

F.C. Dórea  A. Lindberg  B.J. McEwen  C.W. Revie  J. Sanchez 《Preventive veterinary medicine》2014

Syndromic surveillance systems can enhance early disease warning, endemic disease monitoring, or help to accumulate proof of disease freedom. In order to provide immediate feedback to achieve these goals, the health data sources scanned should be acquired continuously, in an automated fashion, and should be stored electronically. Recognizing that data from diagnostic test requests often meet these requirements, two systems designed to automatically extract surveillance information from animal laboratory databases have been developed and are described in this paper. These systems are designed to contribute to early disease detection, as well as the timely management of epidemiological information, in a province of Canada and in Sweden, the areas served by the diagnostic laboratories concerned. Classifying in-coming requests into syndromes, the first step, was the most time-consuming and the least portable step between the two systems. The remaining steps were more easily adjusted from one system to implementation in the other. These steps included: retrospective evaluation of data to create baseline profiles following the removal of excessive noise and aberrations; the identification of temporal effects; prospective evaluation of detection algorithms; and finally real-time monitoring and implementation. Building upon the institutions’ existing data management software, all steps to use those data for the purposes of syndromic surveillance were set up using open source software; as a result this approach could be readily adopted by other institutions. Relatively straight-forward development and maintenance is expected to lead to the incorporation of these systems into each institution's surveillance processes, becoming an indispensable tool for diagnosticians and epidemiologists, as well as stimulating further technical development of such systems.  相似文献   

NOTICE OF A RECENT CONTRIBUTION TO STATISTICAL METHODS     

McEwen GF  Michael EL 《Science (New York, N.Y.)》1920,51(1318):349-350

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Planetary science. Active volcanism on Io     

McEwen AS 《Science (New York, N.Y.)》2002,297(5590):2220-2221

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A closer look at water-related geologic activity on Mars     

McEwen AS  Hansen CJ  Delamere WA  Eliason EM  Herkenhoff KE  Keszthelyi L  Gulick VC  Kirk RL  Mellon MT  Grant JA  Thomas N  Weitz CM  Squyres SW  Bridges NT  Murchie SL  Seelos F  Seelos K  Okubo CH  Milazzo MP  Tornabene LL  Jaeger WL  Byrne S  Russell PS  Griffes JL  Martínez-Alonso S  Davatzes A  Chuang FC  Thomson BJ  Fishbaugh KE  Dundas CM  Kolb KJ  Banks ME  Wray JJ 《Science (New York, N.Y.)》2007,317(5845):1706-1709

Water has supposedly marked the surface of Mars and produced characteristic landforms. To understand the history of water on Mars, we take a close look at key locations with the High-Resolution Imaging Science Experiment on board the Mars Reconnaissance Orbiter, reaching fine spatial scales of 25 to 32 centimeters per pixel. Boulders ranging up to approximately 2 meters in diameter are ubiquitous in the middle to high latitudes, which include deposits previously interpreted as finegrained ocean sediments or dusty snow. Bright gully deposits identify six locations with very recent activity, but these lie on steep (20 degrees to 35 degrees) slopes where dry mass wasting could occur. Thus, we cannot confirm the reality of ancient oceans or water in active gullies but do see evidence of fluvial modification of geologically recent mid-latitude gullies and equatorial impact craters.  相似文献   

Pyroclastic activity at Home Plate in Gusev Crater, Mars     

Squyres SW  Aharonson O  Clark BC  Cohen BA  Crumpler L  de Souza PA  Farrand WH  Gellert R  Grant J  Grotzinger JP  Haldemann AF  Johnson JR  Klingelhöfer G  Lewis KW  Li R  McCoy T  McEwen AS  McSween HY  Ming DW  Moore JM  Morris RV  Parker TJ  Rice JW  Ruff S  Schmidt M  Schröder C  Soderblom LA  Yen A 《Science (New York, N.Y.)》2007,316(5825):738-742

Home Plate is a layered plateau in Gusev crater on Mars. It is composed of clastic rocks of moderately altered alkali basalt composition, enriched in some highly volatile elements. A coarsegrained lower unit lies under a finer-grained upper unit. Textural observations indicate that the lower strata were emplaced in an explosive event, and geochemical considerations favor an explosive volcanic origin over an impact origin. The lower unit likely represents accumulation of pyroclastic materials, whereas the upper unit may represent eolian reworking of the same pyroclastic materials.  相似文献