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排序方式: 共有290条查询结果,搜索用时 250 毫秒
1.
Effect of age on absorption and immune responses to weaning or introduction of novel dietary antigens in pigs 总被引:14,自引:0,他引:14
Pigs weaned at three weeks old absorb food protein antigens from the intestine. The amount of antigen absorbed declines over the next three weeks, and this decline is associated with an increasing level of serum antibody to the fed proteins. There was no difference in the rate of immune elimination of intravenously injected antigen in fed and unfed controls. The reduction of serum antigen is thus likely to reflect reduced absorption, possibly mediated by locally produced antibody. Pigs weaned at 10 weeks old also absorbed antigens and produced an antibody response when introduced to soya; and after three weeks of feeding soya the absorption of antigen was substantially reduced. This latter exclusion was specific for soya as a second novel protein (ovalbumin) was absorbed when introduced to the diet at this time. At six months, pigs no longer absorbed soya proteins when they were introduced to the diet. Furthermore, pigs of this age had serum 'antibody' to soya and other proteins such as keyhole limpet haemocyanin to which they had never been exposed. 相似文献
2.
Newby TJ Stokes CR Huntley J Evans P Bourne FJ 《Veterinary immunology and immunopathology》1979,1(1):37-47
The immune response of pigs fed 200 mg per day of dinitrophenylated bovine gamma globulin has been evaluated in terms of the antibody and lymphocyte responses and of the induction of tolerance and immune exclusion. Although dosing for ten days resulted in a small IgA response as indicated by splenic plaque forming cells, serum antibody could only be detected when dosing was continued for 42 days. secretory antibody was detected at any time. Antigen feeding for two weeks rendered the animals hyporesponsive to subsequent parenteral antigenic challenge but had little effect upon their ability to exclude an oral dose of antigen from the circulation. 相似文献
3.
Jennifer E Stokes S Dru Forrester 《Veterinary Clinics of North America: Small Animal Practice》2004,34(4):909-22, vi
This article provides a source for easy reference, summarizing in one location newly recognized and unusual causes of acute renal failure (ARF) in dogs and cats. Several of the causes discussed in this article have been described previously. New or unusual causes of ARF in dogs and cats include infectious diseases (leptospirosis,borreliosis, and babesiosis), nephrotoxicants (aminoglycosides,vitamin D, and nonsteroidal anti-inflammatory drugs), and plant material (lilies and raisins/grapes). 相似文献
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K. Haverson F. Zuckermann A. Saalmüller J. Lipp B. Aasted C. R. Stokes 《Veterinary immunology and immunopathology》1998,60(3-4):351-365
Fifty-nine monoclonal antibodies (mAb) were assigned to the adhesion section of the Second International Swine CD Workshop. They were analysed for their reactivity to selected lymphoid cell populations, as well as to non-lymphoid cell lines. Cell lysate ELISAS and Western Blot analyses were also carried out. As a result, thirteen separate cluster groups emerged (p>0.95). Workshop assignments for adhesion molecules were made: wCD29/49 for mAbs UCP1D2 (#133) and FW4-101 (#165), and PNK-I (#194) and MUC76A (#025) could be assigned to wCD18. For one cluster (FQ1D7, #161 and 2F4, #069) the cellular distribution and MW were characteristic for MHC Class II, and another cluster comprising several antibodies which appeared to recognise MHC Class I. Other clusters could not be assigned to cell surface structures known to be linked to cellular adhesion, however, two further antibodies, 335-2 (#112) and FG1F6 (#156), could be added to SWC1, and the new SWC8 was defined by MIL3 (#077) and MUC20A (#029), binding a ligand of 29–32 kDa. Clustering for these two antibodies was confirmed by blocking studies. The cellular distribution is known for MIL3, recognising an epitope present on granulocytes, B cells, and a subset of T cells expressing CD8 at high intensity. 相似文献
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Stokes JH 《Science (New York, N.Y.)》1931,74(1925):502-506
8.
Access systems are a necessary element of resource production in bottomland hardwood sites. However, road building may have a detrimental effect on hydrologic function of the site. This report describes initial results of a study designed to examine the effect of different road surfacing treatments on water quality.
Four surfacing treatments installed on two test roads included native soil, native soil with vegetative stabilization, 6 cm of gravel, and 15 cm of gravel over geotextile. During the first flooding season periodic sampling measured floodwater suspended sediments and location of erosion and sediment deposition within the road prism. Initial results suggest that sediment movement was confined to the road right-of-way, with no statistically significant sedimentation effects detected beyond the clearing limits of the road. The study is continuing for another field season. 相似文献
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JI Yun HJ Park MH Park MS Kim JH Choi E Lee SP Gong JM Lim ST Lee 《Reproduction in domestic animals》2014,49(5):705-710
Recently, isolation and in vitro culture of putative spermatogonial stem cells (SSCs) in the domestic cat have been conducted. However, the cellular niche conditions that facilitate the establishment and long‐term maintenance of feline SSCs (FSSCs) have not been described. Therefore, we investigated the type of feeder cells used to stimulate colony formation and growth of FSSCs among the various factors in the FSSC niche. Spermatogonial stem cells isolated from feline testes were cultured on mitotically inactivated testicular stromal cells (TSCs) derived from cats, dogs and mice, and mouse embryonic fibroblasts (MEFs). The formation and growth of colonies derived from SSCs cultured on each type of feeder cell were identified at passage 0, and the morphology, alkaline phosphatase (AP) activity and expression of SSC‐specific genes in surviving colonies were investigated at passage 4. Among these diverse feeder cells, TSCs from cat showed the greatest colony formation, growth and maintenance of FSSCs, and SSC colonies cultured by passage 4 showed a typical dome‐shaped morphology, AP activity and expression of SSC‐specific genes (NANOG, OCT4, SOX2 and CD9). Accordingly, these results demonstrate that feline TSCs could be used as feeder cells to support the establishment and maintenance of SSCs from domestic cats. 相似文献