Comparative efficacy of moxidectin, an ivermectin/clorsulon combination and closantel against immature paramphistomes in cattle     

PF ROLFE  JC BORAY 《Australian veterinary journal》1993,70(7):265-266

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Correlations between ultrasonography findings and hormonal profiles at oestrus in pure Spanish breed mares     

JC ILLERA  MJ ILLERA  G SIL VAN  M ILLERA 《Australian veterinary journal》1993,70(7):273-275

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Peripartal Endocrinology in the Mare and Foetus     

JC Ousey 《Reproduction in domestic animals》2004,39(4):222-231

The endocrine profiles in the periparturient mares are dominated by increasing concentrations of progestagens and decreasing oestrogens. These hormones are produced by precursors from the foetus, metabolized by the placenta and act primarily on the maternal uterus. The circulating concentrations of hormones in maternal plasma, generally, represent a small proportion of those metabolized by the foetus and utero-placental tissues. There is clear evidence that the foetal hypothalamo-pituitary-adrenal (HPA) axis initiates the process of foetal maturation and the hormonal cascade which culminates in parturition at term. The endocrine changes associated with abnormal pregnancy and abortion in late pregnancy are less well understood, as are the hormonal treatments needed to avert these problems. Further work is needed to establish the biological role of the various hormones present in pregnant mares and, in particular, those hormones which control myometrial quiescence.  相似文献   

Effect of a one-off sporidesmin challenge on the milk production of dairy cows     

ZM Matthews  MG Collett  JC Marshall  AC Partridge  PJ Derrick  PJB Edwards 《New Zealand veterinary journal》2018,66(5):261-266

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Detection of Ureaplasma diversum in the upper airways of Australian feedlot cattle     

RJ Barnewall  IB Marsh  PMV Cusack  F Galea  N Sales  JC Quinn 《Australian veterinary journal》2023,101(6):254-257

Bovine respiratory disease (BRD) exerts a major impact on the beef cattle industry nationally and worldwide, with a range of aetiological factors impacting its pathogenesis. Previous research has focussed on an increasing number of bacteria and viruses that have been shown to play a role in eliciting disease. Recently, additional agents have been emerging as potential contributors to BRD, including the opportunistic pathogen Ureaplasma diversum. To determine if U. diversum was present in Australian feedlot cattle and if that presence was linked to BRD, nasal swabs were collected from a cohort of 34 hospital pen animals and compared to 216 apparently healthy animals sampled contemporaneously at feedlot induction and again after 14 days on feed at an Australian feedlot. All samples were subjected to a de novo polymerase chain reaction (PCR) assay targeting U. diversum in combination with other BRD agents. U. diversum was detected at a low prevalence in cattle at induction (Day 0: 6.9%, Day 14: 9.7%), but in a significantly greater proportion of cattle sampled from the hospital pen (58.8%). When considering the presence of other BRD-associated agents, co-detection of U. diversum and Mycoplasma bovis was most common in hospital pen animals receiving treatment for BRD. These findings suggest that U. diversum may be an opportunistic pathogen involved in the aetiology of BRD in Australian feedlot cattle, in combination with other agents, with further studies are warranted to identify if a causal relationship exists.  相似文献   

Profile of Steroid Receptors and Increased Aromatase Immunoexpression in Canine Inflammatory Mammary Cancer as a Potential Therapeutic Target          下载免费PDF全文

PJ De Andrés  S Cáceres  M Clemente  MD Pérez‐Alenza  JC Illera  L Peña 《Reproduction in domestic animals》2016,51(2):269-275

Canine inflammatory mammary cancer (IMC) has been proposed as a model for the study of human inflammatory breast cancer (IBC). The aims of this study were to compare the immunohistochemical expression of aromatase (Arom) and several hormone receptors [estrogen receptor α (ERα), estrogen receptor β (ERβ), progesterone receptor (PR) and androgen receptor (AR)], in 21 IMC cases vs 19 non‐IMC; and to study the possible effect of letrozole on canine IMC and human inflammatory breast cancer (IBC) in vitro using IPC‐366 and SUM‐149 cell lines. Significant elevations of the means of Arom Total Score (TS), ERβ TS and PR TS were found in the IMC group (p = 0.025, p = 0.038 and p = 0.037, respectively). Secondary IMC tumours expressed higher levels of Arom than primary IMC (p = 0.029). Non‐IMC PR‐ tumours contained higher levels of Arom than non‐IMC PR+ tumours (p = 0.007). After the addition of letrozole, the number of IMC and IBC cells dropped drastically. The overexpression of Arom found and the results obtained in vitro further support canine IMC as a model for the study of IBC and future approaches to the treatment of dogs with mammary cancer, and especially IMC, using Arom inhibitors.  相似文献   

A high-resolution radiation hybrid map of the human genome draft sequence     

Olivier M  Aggarwal A  Allen J  Almendras AA  Bajorek ES  Beasley EM  Brady SD  Bushard JM  Bustos VI  Chu A  Chung TR  De Witte A  Denys ME  Dominguez R  Fang NY  Foster BD  Freudenberg RW  Hadley D  Hamilton LR  Jeffrey TJ  Kelly L  Lazzeroni L  Levy MR  Lewis SC  Liu X  Lopez FJ  Louie B  Marquis JP  Martinez RA  Matsuura MK  Misherghi NS  Norton JA  Olshen A  Perkins SM  Perou AJ  Piercy C  Piercy M  Qin F  Reif T  Sheppard K  Shokoohi V  Smick GA  Sun WL  Stewart EA  Fernando J  Tejeda  Tran NM  Trejo T  Vo NT  Yan SC  Zierten DL  Zhao S 《Science (New York, N.Y.)》2001,291(5507):1298-1302

We have constructed a physical map of the human genome by using a panel of 90 whole-genome radiation hybrids (the TNG panel) in conjunction with 40,322 sequence-tagged sites (STSs) derived from random genomic sequences as well as expressed sequences. Of 36,678 STSs on the TNG radiation hybrid map, only 3604 (9.8%) were absent from the unassembled draft sequence of the human genome. Of 20,030 STSs ordered on the TNG map as well as the assembled human genome draft sequence and the Celera assembled human genome sequence, 36% of the STSs had a discrepant order between the working draft sequence and the Celera sequence. The TNG map order was identical to one of the two sequence orders in 60% of these discrepant cases.  相似文献   

Macrolid resistance in Staphylococcus aureus strains from chicken synovitis and dermatitis in industrial production     

W Witte  H Kühn 《Archiv fuer experimentelle veterinaermedizin》1978,32(1):105-114

In outbreaks of synovitis and dermatitis in chicken caused by Staphylococcus (Staph.) aureus we observed erythromycin-resistant strains. These strains belong to the host-specific variety gallinae of Staph. aureus or can not be alloted to one of the known host-specific varieties. The macrolide-resistance-determinant is not carried by a plasmid, presumably it is located on the chromosome. The strains show constitutively cross-resistance to erythromycin, thurimycin, linomycinc and pristinamycin (M-L-S-phenotype). An ecological investigation in a chicken farm has shown that there is no distribution of Staph. aureus-strains from chicken to workers and no occurence of macrolide-resistance in Staph. aureus-strains from the workers.  相似文献   

Substrate choice of territorial male Topeka shiners (Notropis topeka) in the absence of sunfish (Lepomis sp.)     

C. C. Witte  M. L. Wildhaber  A. Arab  D. B. Noltie 《Ecology of Freshwater Fish》2009,18(3):350-359

Abstract –  Topeka shiners ( Notropis topeka ), an endangered minnow species, typically spawn on or around breeding Lepomis sunfish (Centrarchidae) nests. Why spawning Topeka shiners are attracted to these nests is unclear, but having the nesting sunfish provide shiner eggs with improved aeration, a lessening of siltation, and protection from egg predators are possibilities. We tested the substrate utilisation of Topeka shiners in outdoor tanks in the absence of sunfish to determine the shiner's fundamental choice. Shiners were provided with substrate patches of cleaned sand, small gravel, large gravel, and small cobble, and the bare floor of the tank. The substrate above which a male shiner established his territory was used as evidence of choice. A statistically significant choice for sand substrates was demonstrated. This fundamental choice might influence which sunfish nests Topeka shiners use, given that nest substrate characteristics differ both between sunfish species and within species by spawning site location.  相似文献   

Pathogenesis and clinical aspects of Aujeszky's disease in cattle following an experimental infection through the respiratory, digestive and genital organs and through the skin     

W Hopp  K H Witte  D Prager 《Zentralblatt für Veterin?rmedizin. Reihe B. Journal of veterinary medicine. Series B》1985,32(4):287-305

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