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Zohreh Hojati Farzaneh Omidi Moein Dehbashi Bahram Mohammad Soltani 《Iranian Biomedical Journal》2021,25(1):62
Background:Among different roles of miRNAs in AD pathogenesis, hsa-miR-494-3p and hsa-miR-661 functions are poorly understood. Methods:To obtain the gene targets, gene networks, gene ontology, and enrichment analysis of the two miRNAs, some web servers were utilized. Furthermore, the expressions of these miRNAs were analyzed by qRT-PCR in 36 blood sera, including 18 Alzheimer’s patients and 18 healthy individuals. Results:The in silico analysis demonstrated the highlighted roles of metabolic and cellular response to stress pathways engaged in circulating hsa-miR-494-3p and hsa-miR-661 in AD. The qRT-PCR analysis showed that the downregulated expression level of hsa-miR-661 was statistically significant (p < 0.05). Also, the ROC curve of hsa-miR-661 displayed the significant AUC (p = 0.01). Conclusion:Based on our findings, the metabolic and cellular responses to stress pathways are closely connected to these two miRNAs functions. Besides, the qRT-PCR and Roc curve determined hsa-miR-661 could be as a biomarker for diagnosis or prognosis of AD patients. Key Words: Alzheimer’s disease, Serum, Circulating microRNAs 相似文献
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Laboratory bioassay of the two fungiMetarbizium anisopliae (Metschnikoff) Sorokin andVerticillium indicum (Petch) Gams was carried out under 26±1 C° and 75±2% R. H. This is the first study on the efficiency of both mycopathogens against the termiteCryptotermes brevis (Walker). Using the highest concentration ofM. anisopliae (43.5 × 105 V.S/ml), percentages of mortality after 4 weeks from treatment of the termiteC. brevis fed on filter paper or wood were 100 and 93.33, respectively. On the same time, the highest concentration of the fungiV. indicum (34.3 × 105 V.S/ml) resulted in the mortality percentages of 83.33 and 70, respectively, fed on filter paper and wood. In general, the data indicated more susceptibility of the termiteC. brevis to the entomopathogenic fungusM. anisopliae than to the fungusV. indicum. M. anisopliae could be considered as a promising potential mycopathogen against the termiteC. brevis. This study, presenting new approach of the alternative dry wood termite control, might be applied in the future. 相似文献
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Seyed Mohammad Moein Sadeghi John Toland Van Stan Thomas Grant Pypker Jelveh Tamjidi Jan Friesen Moein Farahnaklangroudi 《European Journal of Forest Research》2018,137(1):121-130
The temporal dynamics of forest canopy rainfall partitioning are important to forest ecology and management as it influences all subsequent hydrological processes along the rainfall-to-discharge flow path. Despite a growing body of literature on the importance of coupled hydrological–ecological interactions during periodic forest life cycle events, little work has examined how canopy rainfall partitioning varies across transitional leaf states (between the leafed vs. leafless states). This study analyzed a 3 year field monitoring campaign for two tree species in semiarid Iran (Robinia pseudoacacia and Platanus orientalis) to describe rainfall partitioning dynamics across the full-leaf, senescence, leafless, and leafing states. Crown saturation point, canopy storage capacity, free throughfall coefficient and the ratio of wet canopy evaporation rate to mean rainfall intensity were related to decreases/increases in plant area index and canopy closure. The high variability of rainfall partitioning observed in this study highlights the importance of transitional leaf states in the temporal characterization of water inputs to forest surfaces and boundary layer. 相似文献
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Azade Deljouei Seyed Mohammad Moein Sadeghi Ehsan Abdi Markus Bernhardt-Römermann Emily Louise Pascoe Matteo Marcantonio 《European Journal of Forest Research》2018,137(6):759-770
The ‘road-effect zone’ is a concept developed to describe the impact of road construction on the surrounding area. Although many aspects of the road-effect zone have been investigated, the road-effect zone on soil properties (pH, bulk density, soil moisture, electrical conductivity, organic matter (%), C (%), total N (%), available Na, Ca, Mg, P, and K), light regimes (leaf area index and canopy cover), and a Raunkiaer’s life-form classification of plants remains poorly understood, especially in oriental beech (Fagus orientalis Lipsky) forests. Hence, the main aims of this research were to estimate the extent of the road-effect zone and to identify the main environmental changes due to forest roads. Specifically, we aimed to evaluate road-effects on: (1) the composition of herbaceous species and tree regeneration (up to 100 m distance from the forest road); (2) the light regime; and (3) soil properties, potentially related to changes in ecosystem functions and composition. We observed that forest roads can have significant impacts on soil, stand characteristics, and vegetation composition. The estimated road-effect zone extended up to 30 m from the road edge. Landscape planners should be aware that road-effect zones can potentially influence the ecology and environmental conditions of an area up to 30 m from the road edge. 相似文献
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Laboratory bioassay of the two fungiMetarbizium anisopliae (Metschnikoff) Sorokin andVerticillium indicum (Petch) Gams was carried out under 26±1 C° and 75±2% R. H. This is the first study on the efficiency of both mycopathogens against the termiteCryptotermes brevis (Walker). Using the highest concentration ofM. anisopliae (43.5 × 105 V.S/ml), percentages of mortality after 4 weeks from treatment of the termiteC. brevis fed on filter paper or wood were 100 and 93.33, respectively. On the same time, the highest concentration of the fungiV. indicum (34.3 × 105 V.S/ml) resulted in the mortality percentages of 83.33 and 70, respectively, fed on filter paper and wood. In general, the data indicated more susceptibility of the termiteC. brevis to the entomopathogenic fungusM. anisopliae than to the fungusV. indicum. M. anisopliae could be considered as a promising potential mycopathogen against the termiteC. brevis. This study, presenting new approach of the alternative dry wood termite control, might be applied in the future. 相似文献
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