Crystalluria. Observations, interpretations, and misinterpretations     

C A Osborne  T D O'Brien  H K Ghobrial  L Meihak  J B Stevens 《Veterinary Clinics of North America: Small Animal Practice》1986,16(1):45-65

Crystalluria results from oversaturation of urine with crystallogenic substance. However, oversaturation may occur as a result of in vitro as well as in vivo events. The microscopic appearance of crystals only represents a tentative identification of their composition because variable conditions associated with their formation, growth, and dissolution may alter their appearance. Definitive identification is dependent on physical methods such as optical crystallography, x-ray diffraction, and electron microscopic analysis.  相似文献   

Traumatic luxation of the cubital joint (elbow) in dogs: 44 cases (1978-1988).     

M G O'Brien  R J Boudrieau  G N Clark 《Journal of the American Veterinary Medical Association》1992,201(11):1760-1765

The medical records from 44 dogs with traumatic luxation of the cubital joint were reviewed. Closed reduction was performed in 35 dogs, and open reduction in 9 dogs. Excellent or good results were achieved in 31 of 35 dogs (88.6%) treated by closed reduction and in 5 of 9 dogs (55.6%) treated by open reduction. Collateral ligament repair, performed in 5 dogs, did not appear to affect the prognosis. Factors such as body weight and type and duration of external coaptation also did not appear to influence the outcome. Increased dysfunction associated with open reduction most likely was caused by the chronic nature of the dislocation, iatrogenic damage to the articular cartilage during reduction, or both. A good prognosis for return to normal function with minimal gait abnormality can be expected in most cases of traumatic luxation of the cubital joint treated by early closed reduction.  相似文献   

Pathogenicity of Fusarium oxysporum f. sp. Cepae and its interaction with Pyrenochaeta terrestris on onion   总被引：1，自引：0，他引：1  

August E. Kehr  Muriel J. O'Brien  Elmo W. Davis 《Euphytica》1962,11(2):197-208

Onion breeding lines known to be resistant to Pyrenochaeta terrestris showed, in several locations, root-pruning symptoms that have been usually associated with only the action of P. terrestris. Fusarium oxysporum f. sp. cepae was invariably isolated from affected roots and the stem-plate area of these pink-root-resistant lines. Symptoms not commonly associated with the action of Fusarium, including darkening of dry scales of yellow bulbs and a reddening of scales of white bulbs, were noted. Controlled tests were conducted to establish (a) the pathogenicity of four isolates of F. oxysporum f. sp. cepae, (b) the reaction of onion breeding lines to inoculation at various temperatures with both the pink root and the Fusarium bulb rot organism, and (c) the pathogenic interaction of F. oxysporum f. sp. cepae with P. terrestris. The Fusarium isolates were pathogenic over a wide range of temperatures (20 to 38°C.). Host reaction to the organisms in combination depended on the level of susceptibility that was the greater to one or the other organism. Resistance to one did not markedly modify susceptibility to the other when both were present. Resistance to F. oxysporum f. sp. cepae was found in several onion lines.Horticulturist, Pathologist, and Horticulturist, respectively, United States Department of Agriculture, Beltsville, Maryland, U.S.A.  相似文献   

Inherited peripheral neuropathies in dogs and cats.     

Joan R Coates  Dennis P O'Brien 《Veterinary Clinics of North America: Small Animal Practice》2004,34(6):1361-1401

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Removal of hemangiosarcoma cells from canine blood with a cell salvage system and leukocyte reduction filter          下载免费PDF全文

Brittany Ciepluch DVM  MS  Heather Wilson‐Robles DVM  DACVIM  Gwendolyn Levine DVM  DACVP  Roger Smith DVM  PhD  Gus A. Wright PhD  Tasha Miller BS  Maureen T. O'Brien DVM  MS  DACVP  Kelley M. Thieman Mankin DVM  MS  DACVS‐SA 《Veterinary surgery : VS》2018,47(2):293-301

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A Homozygous RAB3GAP1:c.743delC Mutation in Rottweilers with Neuronal Vacuolation and Spinocerebellar Degeneration          下载免费PDF全文

T. Mhlanga‐Mutangadura  G.S. Johnson  A. Ashwini  G.D. Shelton  S.A. Wennogle  G.C. Johnson  K. Kuroki  D.P. O'Brien 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(3):813-818

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Australian Cattle Dogs with Neuronal Ceroid Lipofuscinosis are Homozygous for a CLN5 Nonsense Mutation Previously Identified in Border Collies          下载免费PDF全文

A. Kolicheski  G.S. Johnson  D.P. O'Brien  T. Mhlanga‐Mutangadura  D. Gilliam  J. Guo  T.D. Anderson‐Sieg  R.D. Schnabel  J.F. Taylor  A. Lebowitz  B. Swanson  D. Hicks  Z.E. Niman  F.A. Wininger  M.C. Carpentier  M.L. Katz 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(4):1149-1158

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Experimental Neospora Caninum Infection in Pregnant Dairy Heifers Raises Concentrations of Pregnancy‐Associated Glycoproteins 1 and 2 in Foetal Fluids          下载免费PDF全文

R Mur‐Novales  F López‐Gatius  B Serrano‐Pérez  I García‐Ispierto  L Darwich  O Cabezón  NM de Sousa  JF Beckers  S Almería 《Reproduction in domestic animals》2016,51(2):282-286

Plasma concentrations of PAG‐1 are used for pregnancy diagnosis and as a marker of placental/foetal well‐being, while those of PAG‐2 may be an indicator of abortion risk in Neospora caninum‐infected cows. Studies have shown that N. caninum infection modifies PAG‐1 and PAG‐2 patterns in maternal blood plasma. However, no prior work has examined the effects of N. caninum infection on concentrations of PAGs in foetal fluids. In this study, PAG‐1, PAG‐2 and pH levels were determined in the amniotic and allantoic fluids of foetuses collected at 152 days of gestation from control uninfected dams and from dams experimentally infected with N. caninum on Day 110 of gestation. Foetal fluids from infected foetuses had significantly higher PAG‐2 concentrations (p = 0.026) and pH values (p = 0.02) than fluids from non‐infected foetuses. In infected foetuses, significantly higher concentrations of PAG‐1 (p < 0.001) and PAG‐2 (p < 0.001) were detected in fluid samples showing antibodies against N. caninum than those without antibodies. Moreover, pH values were significantly higher (p = 0.011) in foetal fluid samples with antibodies than in samples from non‐infected foetuses. In conclusion, this is the first report on the effect of N. caninum infection on PAG levels in foetal fluids. Our results indicate that following the experimental infection of dams with N. caninum on Day 110 of gestation, foetal fluids collected from the infected foetuses of these dams featured higher PAG‐1 and PAG‐2 levels and pH values than fluids from non‐infected controls, provided that the samples tested showed the presence of antibodies. The clinical implications of these findings are that following infection with N. caninum, most cows will experience some level of placental damage and that this injury correlates with foetal fluid PAG levels and pH.  相似文献   

The clinical utility of the right lateral intercostal ultrasound scan technique in dogs     

Brinkman EL  Biller DS  Armbrust LJ  O'Brien RT 《Journal of the American Animal Hospital Association》2007,43(4):179-186

When performing abdominal ultrasonography in dogs, the right aspect of the liver, porta hepatis, right kidney, right adrenal gland, pancreas, and duodenum are often not fully visible from a ventral, or subcostal, approach. The right lateral intercostal plane is an alternative approach that allows evaluation of these structures. This report provides multiple case examples that demonstrate the sonographic anatomy via the right intercostal approach. Other cases are included to demonstrate indications for this approach. Animals in which the right intercostal approach may prove most useful include large- and giant-breed dogs; deep-chested dogs; dogs with gas distention of the stomach, duodenum, and colon; dogs with microhepatia; and those with abdominal effusion and pain.  相似文献   

Xerostomia, xerophthalmia, and plasmacytic infiltrates of the salivary glands (Sjögren's-like syndrome) in a cat     

Canapp SO  Cohn LA  Maggs DJ  Miller MA  Kerl ME  O'Brien DP 《Journal of the American Veterinary Medical Association》2001,218(1):59-65

A 2.5-year-old domestic shorthair cat was evaluated because of dysphagia and weight loss of 4 weeks' duration. MIld blepharospasm and conjunctival hyperemia were evident in both eyes, oral mucous membranes were tacky on palpation, and salivary glands were enlarged. Results of a Schirmer tear test were 0 mm/min for both eyes. Administration of atropine did not cause salivation or caused secretion fo thick rope-like saliva. Examination of biopsy specimens of salivary glands revealed a plasmacytic infiltrate. Sj?gren's syndrome (SS) was diagnosed. Oral administration of prednisone was instituted but was discontinued after a minimal positive response was evident 6 weeks after initiation of treatment. Palliative treatment with a 6% solution of pilocarpine 4 to 5 times/d, cyclosporine, hylan A, and neomycin-polymyxin-bacitracin ophthalmic ointment resulted in clinical improvement in the cat. Although reported rarely in animals, SS may be more common than currently is recognized. Most treatment regimens for SS are aimed at alleviating clinical signs.  相似文献