Hereditary multiple exostoses: clinicopathologic features of a comparative study in horses and man.     

J L Shupe  N C Leone  A E Olson  E J Gardner 《American journal of veterinary research》1979,40(6):751-757

Investigation of hereditary multiple exostoses in horses under controlled research conditions for 10 years and epidemiologic studies that have spanned up to five generations of human families contain notable similarities. The present study demonstrated that a single dominant autosomal gene is responsible for hereditary multiple exostoses in horses and man. Affected individuals transmit this trait to approximately 50% of their progeny, whereas nonaffected individuals do not transmit the condition to their offspring. The tumors in affected horses are most often present at birth. They tend to be bilaterally symmetrical and vary in size, shape, and texture. Those on the legs generally do not appear to enlarge as the animal matures, but others, notably those on the ribs and scapulae, enlarge until skeletal maturity, Histologically, the tumors appear as typical ostosteochondromas in both horse and man. Sarcomatous transformations have not yet been detected after 10 years in horses, although such changes are occasionally reported in the similar disease condition in man. The remarkable similarities of hereditary multiple exostoses in the horse to that in man provide an opportunity for comparative biomedical study.  相似文献   

Long-term deep sedation using Zoletil and haloperidol for the treatment of streptococcal pneumonia in an orangutan (Pongo pygmaeus)     

Paolo MARTELLI  Serena OH 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(5):809

A 13-year-old Bornean orangutan diagnosed with life threatening Streptococcus pyogenes broncho-pneumonia was kept in a state of deep sedation for 20 days via continuous intra-venous (IV) infusion of zolazepam -tiletamine and IV haloperidol to allow consistent IV administration of ceftazidime and gatifloxacine. The use of long-term deep sedation allowed carrying out a particularly demanding treatment not generally associated with zoological patients. The treatment was ultimately successful.  相似文献   

Chemical and nutritional characteristics of Cannabis sativa L. co-products     

Alessandro Vastolo  Serena Calabrò  Severina Pacifico  Bossima Ivan Koura  Monica Isabella Cutrignelli 《Journal of animal physiology and animal nutrition》2021,105(Z1):1-9

Cannabis sativa L. is an annual herbaceous plant. It was used for centuries to obtain different products. In the last century, hemp cultivation was forbidden due to the psychoactive effects of tetrahydrocannabinol acid (THCA). In the last years, new strains, characterized by high cannabidiolic acid (CBDA) and low THCA level, were developed renewing the interest in hemp cultivation to obtain food or to extract essential oils from flowers. All these processes produce many residues with different chemical–physical characteristics. In order to evaluate their potential use also in animal nutrition, some hemp co-products were evaluated. Two different co-products of seed processes (flour and oil) and two co-products obtained trimming the flowers, differing in granulometry were used. The samples were analysed for chemical composition and evaluated in vitro using the gas production technique with buffaloes' ruminal inoculum. All hemp co-products showed interesting nutritional characteristics, such as crude protein content always higher than 20% on a dry matter basis, and high neutral detergent fibre concentration partially lignified. The in vitro gas production parameters at 120 h of incubation showed quite low fermentability testified by the low organic matter degradability and cumulative gas volume (OMD from 28.09 to 45.64% and OMCV from 110 to 164 ml/g, respectively). Also, the methane produced after 24 h of incubation was particularly low (from 1.78 to 11.73 ml/g dOM). These results could be due to the high lipid and ash amounts or to the CBDA content that probably affected the CH₄ formation processes. According to preliminary results obtained by this study, it is possible to hypothesize that these co-products could be useful to mitigate the methane production into the rumen. Further studies are necessary in order to evaluate the correct inclusion into the diet for ruminants.  相似文献   

An inactivated vaccine for the control of bluetongue virus serotype 16 infection in sheep in Italy     

Savini G  Ronchi GF  Leone A  Ciarelli A  Migliaccio P  Franchi P  Mercante MT  Pini A 《Veterinary microbiology》2007,124(1-2):140-146

Because no suitable products are at the moment available to safely control the spread of BTV-16 in Europe, an inactivated vaccine was produced from the reference field isolate of bluetongue virus serotype 16. One group of six sheep was vaccinated subcutaneously with the inactivated vaccine twice, on days 0 and 28, whereas a second group of eight sheep was inoculated with saline solution and used as mock-vaccinated control animals. Seventy-eight days after the first vaccination, all sheep were inoculated subcutaneously with a suspension containing 10(6.3) TCID(50) of a virulent reference BTV-16 isolate. Apart from a transient inflammatory reaction at the injection site, no adverse effects were reported following vaccination. All vaccinated animals developed high titres (7.3-9.3log(2)(ED50%/50 microl)) of virus-specific neutralising antibodies and were resistant to challenge with BTV-16. Conversely, following challenge, control animals developed hyperthermia and long lasting high-titre viraemia.  相似文献   

Identification of emesis-causing Bacillus cereus strains by polymerase chain reaction: preliminary results     

Colavita G  Rotili M  Leone A  Vergara A  Sammarco ML  Ripabelli G 《Veterinary research communications》2007,31(Z1):351-353

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Bioactive Compounds in Wild Asteraceae Edible Plants Consumed in the Mediterranean Diet     

Panfili  Gianfranco  Niro  Serena  Bufano  Annarita  D’Agostino  Annacristina  Fratianni  Alessandra  Paura  Bruno  Falasca  Luisa  Cinquanta  Luciano 《Plant foods for human nutrition (Dordrecht, Netherlands)》2020,75(4):540-546

Plant Foods for Human Nutrition - Three wild edible plant species belonging to the Asteraceae family, Crepis vesicaria L. (s.l.), Sonchus asper (L.) Hill s.l., and Sonchus oleraceus L., usually...  相似文献   

Country‐wide analysis of large wood as a driver of fish abundance in Swedish streams: Which species benefit and where?     

Serena Donadi  Leonard Sandin  Carl Tamario  Erik Degerman 《水产资源保护:海洋与淡水生态系统》2019,29(5):706-716

Rapid and Sensitive Detection of Apple stem pitting virus in Apple Trees Through RNA Amplification and Probing with Fluorescent Molecular Beacons     

Klerks MM  Leone G  Lindner JL  Schoen CD  van den Heuvel JF 《Phytopathology》2001,91(11):1085-1091

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The fermentative capacity of growing pigs and adult sows fed diets with contrasting type and level of dietary fibre     

Henry Jrgensen  Anja Serena  Mette S. Hedemann  Knud Erik Bach Knudsen 《Livestock Science》2007,109(1-3):111-114

Adult sows have a more developed gastro-intestinal system than young growing pigs resulting in a superior capacity to digest fibrous components. The main objective of this study was to describe the capacity of sows and growing pigs to digest the fibre components in concentrated low dietary fibre (DF) diet and two high DF diets similar in DF but with contrasting DF solubility. Six sows and four growing pigs were fitted with a simple T-cannula at the terminal ileum. Each balance experiment consisted of a 7-day initial period followed by a 3-day collection of faeces and a 2 or 3-day collection of ileal digesta for growing pigs and adult sows, respectively. When feeding diets with high proportions of soluble non-starch polysaccharides (NSP), the difference in fermentation capacity between growing pigs and adult sows was small. The adult sows showed a higher fermentative capacity, evidenced by a higher fermentation and a higher methane production, when high fibre diet with high amount of insoluble fibre was fed.  相似文献   

COMBINATION OF RADIATION THERAPY AND FIROCOXIB FOR THE TREATMENT OF CANINE NASAL CARCINOMA          下载免费PDF全文

Simona Cancedda  Silvia Sabattini  Giuliano Bettini  Vito F. Leone  Paola Laganga  Federica Rossi  Rossella Terragni  Giacomo Gnudi  Massimo Vignoli 《Veterinary radiology & ultrasound》2015,56(3):335-343

Carcinomas represent two‐thirds of canine nasosinal neoplasms. Although radiation therapy (RT) is the standard of care, the incidence of local recurrence following treatment is high. Cyclooxygenase‐isoform‐2 (COX‐2) is expressed in 71–95% of canine nasal carcinomas and has been implicated in tumor growth and angiogenesis. Accordingly, COX‐2 inhibition seems rational to improve outcome. Dogs with histologically confirmed, previously untreated nasal carcinomas were randomized to receive the combination of a selective COX‐2 inhibitor (firocoxib) and palliative RT (Group 1) or RT and placebo (Group 2). Patients were regularly monitored with blood tests, urinalysis, and computed tomography. Pet owners were asked to complete monthly a quality‐of‐life questionnaire. Twenty‐four dogs were prospectively enrolled. According to Adams modified system, there were five stage 1, five stage 2, three stage 3, and 11 stage 4 tumors. Two dogs had metastases to regional lymph nodes. Median progression‐free interval and overall survival were 228 and 335 days in Group 1 (n = 12) and 234 and 244 days in Group 2 (n = 12). These differences were not statistically significant. The involvement of regional lymph nodes was significantly associated with progression‐free interval and overall survival (P = 0.004). Quality of life was significantly improved in Group 1 (P = 0.008). In particular, a significant difference was observed for activity and appetite. Although not providing a significant enhancement of progression‐free interval and overall survival, firocoxib in combination with RT is safe and improved life quality in dogs with nasal carcinomas.  相似文献