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Recombinant technology is relatively new to veterinary medicine. It combines safety, purity, potency, and efficacy in the vaccine. Its positive features include not exposing the vaccinate to the pathogen, the lack of need for adjuvants, and stability that allows some vaccine to remain viable at ambient temperatures. These recombinants can receive multiple genetic inserts and present an opportunity to have multiple combination vaccines for use in animals. Licensed recombinant vaccines in veterinary medicine include those protecting against Lyme disease, pseudorabies, rabies, canine distemper, Newcastle disease, and a strain of avian influenza.  相似文献   
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BACKGROUND: Age-related changes in hematologic values are known to occur in many species. Few published studies include repeated measurements of hematologic parameters in calves during the first months of life. OBJECTIVE: The aim of the present study was to monitor hematologic values by sequential measurements from birth to 6 months of age in 15 healthy calves of the Norwegian Red breed, and compare the results to reference intervals for adult, lactating dairy cows. METHODS: Fifteen clinically healthy calves were sampled every week during the first 5 weeks of life and every month thereafter until 6 months of age. Hematologic values were measured using the ADVIA 120 hematology system. Reference intervals were determined for 75 healthy adult cows of the same breed. RESULTS: Compared with adult reference intervals, the MCV was lower and the RBC count was higher in calves throughout the investigation period. Hemoglobin concentration stayed largely within the adult reference interval. Mean MCHC was lower than adult values for 5 weeks, then increased and reached adult values by weeks 10-12. The mean lymphocyte count for calves reached adult reference values at weeks 6-8, and the mean monocyte count increased steadily until weeks 14-16. For most leukocytes, interindividual variation was larger during the first 5-8 weeks of life. The mean platelet count for calves was higher than the adult reference interval until weeks 19-21 of age. CONCLUSIONS: Age-specific reference intervals for calves from birth to 6 month of age are needed for RBC count, MCV, MCHC, red cell distribution width, and platelet and lymphocyte counts.  相似文献   
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It has been hypothesised that a relatively high water intake results in a lower food digestibility. The influence of water:food ratios on the metabolisability of a diet was investigated. With ad libitum water and food the water:food ratios varied between 1.17 and 2.47 and showed a positive relationship with metabolisable energy. In groups of hens receiving 40 g food and water sufficient to provide water:food ratios of 1, 2, 3 and 4, the results showed a non-significant negative regression of apparent metabolisable energy with water:food ratios.  相似文献   
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