Role of Rats in the Transmission of Trichinella spiralis spiralis to Swine          下载免费PDF全文

Smith HJ  Kay ED 《The Canadian veterinary journal. La revue veterinaire canadienne》1987,28(9):604

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Initial analytic quality assessment and method comparison of an immunoassay for adrenocorticotropic hormone measurement in equine samples          下载免费PDF全文

Katherine L. Irvine  Kay Burt  Andrew J. Hill  Stephanie Shaw  Kostas Papasouliotis 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2016,45(1):154-163

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Genomic hypomethylation in neoplastic cells from dogs with malignant lymphoproliferative disorders     

Pelham JT  Irwin PJ  Kay PH 《Research in veterinary science》2003,74(1):101-104

DNA methylation is an epigenetic modification in which a methyl group is added usually to the fifth carbon position of a cytosine residue. Dysregulation of this process is an important molecular event which has been shown to be associated with neoplastic transformation and tumour progression in humans and mice. Features of methylation dysregulation in many different types of neoplasms include general genomic hypomethylation, focal hypermethylation, and altered expression of genes which encode a series of DNA (cytosine-5) methyltransferases. Interestingly, many types of neoplasia that are recognised in humans also develop spontaneously in the dog. By comparing the restriction patterns of MspI and HpaII, this study demonstrates that as in human, genomic hypomethylation is a feature of neoplastic cells in the majority of canine lymphoma cases and approximately one-third of canine leukemia cases confirming that dysregulation of the DNA methylating machinery is implicated in malignant transformation of lymphoid cells in some dogs.  相似文献   

Grade III mastocytoma in a donkey     

Kay G  Noursaid I  El Hamidi M  Perron MF 《The Veterinary record》2003,152(9):266-267

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A foal from a mule in Morocco     

Kay G 《The Veterinary record》2003,152(3):92

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Neuronal ceroid-lipofuscinosis in Borderdale sheep     

Jolly RD  Arthur DG  Kay GW  Palmer DN 《New Zealand veterinary journal》2002,50(5):199-202

AIM: To describe the gross and histological lesions of a neurological disease in Borderdale sheep characterised clinically by blindness and circling, as a basis to its classification. METHODS: Formalin-fixed tissues were processed into paraffin wax and epoxy resin for light and electron microscopy of variously stained sections. RESULTS: Lesions were those of a lysosomal storage disease with severe neurodegeneration of the cerebral cortex. The staining reactions, autofluorescence and ultrastructure of storage material allowed the diagnosis of neuronal ceroid-lipofuscinosis associated with the accumulation of subunit-c of mitochondrial ATP synthase. CONCLUSIONS: The severity of neurodegeneration and minor differences in the ultrastructure of storage material implied that this was a different disease from other forms of ovine ceroid-lipofuscinosis that accumulate subunit-c of mitochondrial ATP synthase. An autosomal recessive mode of inheritance is considered probable. Although of only minor economic importance, this disease may be important to research into the group of ceroid-lipofuscinoses as a whole.  相似文献   

Wildlife Mammals as Research Models: In the Laboratory and Field          下载免费PDF全文

Kay G. Mehren 《The Canadian veterinary journal. La revue veterinaire canadienne》1997,38(7):455

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Prognosis for Neonatal Foals in an Intensive Care Unit     

Martin Furr  Mary Kay Tinker  Lucy Edens 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1997,11(3):183-188

This study was conducted to develop an equation for the prediction of outcome in neonatal foals undergoing treatment in an intensive care unit (ICU). Fifty-three physical examination, historical, and clinicopathologic variables were analyzed from the records of 99 neonatal foals (<14 days of age) treated in the neonatal ICU of the Equine Medical Center. The outcome was recorded and the results were categorized into either surviving or nonsurviving groups. The mean values for the 2 groups were compared, and variables that differed significantly between the two groups were retained and used to construct a logistic regression equation. Retained variables were heart rate, temperature, and neutron phil count. The predictive equation then was tested prospectively in 2 additional groups of foals from 2 separate ICUs. The predicted outcome was compared to the actual outcome, and performance variables were calculated. Sensitivity (.83), specificity (.87), negative predictive value (.72), and positive predictive value (.93) were determined for foals from one neonatal ICU; the sensitivity (.83), specificity (.44), negative predictive value (.44), and positive predictive value (.83) were lower for foals at a second, separate ICU.  相似文献   

GEOSYNCLINES IN CONTINENTAL DEVELOPMENT     

Kay M 《Science (New York, N.Y.)》1944,99(2580):461-462

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Correction to: Agroforestry can enhance foraging and nesting resources for pollinators with focus on solitary bees at the landscape scale     

Kay  Sonja  Kühn  Elisabeth  Albrecht  Matthias  Sutter  Louis  Szerencsits  Erich  Herzog  Felix 《Agroforestry Systems》2021,95(5):1015-1015

Agroforestry Systems - A correction to this paper has been published: https://doi.org/10.1007/s10457-021-00641-7  相似文献