Bisphenol A and nonylphenol bioconcentration in spotted halibut Varaspar variegates     

Ho chul  LEE  Kiyoshi  SOYANO  Atsushi  ISHIMATSU  Masaki  NAGAE  Shinya  KOHRA  Yasuhiro  ISHIBASHI  Koji  ARIZONO  Yuji  TAKAO 《Fisheries Science》2004,70(1):192-194

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Detection of thyroid hormone receptors in the olfactory system and brain of wild masu salmon,Oncorhynchus masou (Brevoort), during smolting by in vitro autoradiography     

H. KUDO  Y. TSUNEYOSHI  M. NAGAE  S. ADACHI  K. YAMAUCHI  H. UEDA  H. KAWAMURA 《Aquaculture Research》1994,25(Z2):171-181

Thyroid hormone regulates a number of physiological functions during smolting in salmonids. However, the target sites and roles of thyroid hormone in the central nervous system (CNS) are not known in detail. We detected thyroid hormone-specific binding sites (i.e. thyroid hormone receptors) in the olfactory epithelium and the brain (the olfactory bulb, the telencephalon, the mid-brain and the cerebellum) of wild masu salmon, Oncor- hynchus masou (Brevoort), during smolting by means of in vitro autoradiography with frozen sections. A saturation experiment with the brain indicated the presence of a single class of binding sites of high affinity. T3-specific binding was detected in the olfactory epithelium and in all regions of the brain except the olfactory bulb. The T3-specific binding value in the olfactory epithelium was higher than in all other regions of the brain. This binding value in the olfactory epithelium increased at the full-smolt stage. The presence of thyroid hormone receptors in various regions of the CNS suggests that thyroid hormone plays an important role in the functional change in the brain and the olfactory epithelium during smolting.  相似文献