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排序方式: 共有308条查询结果,搜索用时 15 毫秒
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Yuichi Kinoshita Katsuhiko Yoshizawa Yuko Emoto Michiko Yuki Takashi Yuri Nobuaki Shikata Susan A. Elmore Airo Tsubura 《Journal of toxicologic pathology》2016,29(1):53-59
Primary ovarian tumors are generally uncommon in rats used in toxicologic studies. A malignant Sertoli cell tumor was present in the ovary of a 19-week-old female Sprague Dawley rat. Macroscopically, the mass was white and firm, 10 × 13 × 17 mm in size, and located in the right ovary. Histopathologically, the mass was composed of nests of pleomorphic cells, which formed seminiferous-like tubules separated by a thin fibrovascular stroma. The tubules were lined by tumor cells, which had basally located nuclei and abundant eosinophilic and vacuolated cytoplasm. In some areas, the tumor cells were arranged in a retiform growth pattern, mimicking a rete testis/ovarii. Disseminated metastases to the surfaces of the mesentery, spleen and liver were also present. Immunohistochemically, many tumor cells were strongly positive for vimentin, estrogen receptor α and Ki 67. Some tumor cells were positive for pancytokeratin and inhibin α. These findings closely resemble those of an ovarian-derived human malignant Sertoli cell tumor. From our review of the literature, we believe this is the first report of a spontaneous malignant Sertoli cell tumor in the ovary of a young laboratory rat. This case might provide useful historical control information for rat toxicity studies. 相似文献
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Tomato fruit quality as influenced by the interactions between agricultural techniques and harvesting period
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Tomato (Solanum lycopersicum Mill) is an important crop in terms of its economic and nutritional value. Many factors, including cultivar, climate, geography, geochemistry, and agricultural practice, can affect its nutrient concentrations. An HJ‐biplot study was performed to examine the effects of cultivar (Dorothy, Boludo, Dominique, Thomas, and Dunkan), agricultural practices, climatic factors, and their interactions. Significant differences were analyzed using a one‐way ANOVA. All samples were collected and assayed at the same degree of ripeness. In the conventional and organic tomato samples, those harvested from December to April had the highest concentrations of fructose, glucose, citric acid, malic acid, ascorbic acid, protein, Na, and Mg, while those harvested in October had the highest concentrations of lycopene and hydroxycinnamic acid. There were high concentrations of Ca, P, Zn, and Cu in the no‐soil tomatoes. Conventional and organic cultivation practices showed similar results with respect to the collection period, both presenting high organic compound concentrations, while high mineral concentrations seemed to correspond to the no‐soil practice. No clear pattern was observed among the different cultivars, perhaps due to all the samples having been collected at the same degree of ripeness. 相似文献
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Robert Manuel L. Juárez-Gómez Juan Chaires-Pacheco Mariana Peña-Ramírez Yuri J. 《New Forests》2020,51(2):335-347
New Forests - Spanish red cedar, Cedrela odorata L. (Meliaceae), is a valuable timber tree in tropical American forests. Existing demand for elite individuals endangers the conservation of... 相似文献
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Sugisawa H Itou T Ichimura Y Sakai T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(12):1113-1116
Bovine milk contains various immunoreactive components, and the activation of polymorphonuclear leukocytes (PMNLs) function in breast-fed infants has been reported. In this study, the effect of milk on the oxidative burst of bovine PMNLs was investigated in vitro. When PMNLs were incubated with 0.1% colostrum or normal milk, the oxidative burst induced by serum-opsonized Staphylococcus aureus was enhanced, and the enhancement declined dose-dependently. The enhancement of the oxidative burst by milk was not due to opsonins but the priming activities. Also, the phorbol 12-myristate 13-acetate (PMA)-induced oxidative burst increased after incubation with 0.1% colostrum, but the colostral enhancement of the oxidative burst was unaffected by the incubation time. These results suggest that bovine milk contains oxidative burst promoting factor(s). 相似文献
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Response of western flower thrips, Frankliniella occidentalis (Pergande), to selection for resistance to insecticides commonly used to control this pest in Murcia (south-east Spain) was studied under field and laboratory conditions. In the field, plots within sweet pepper crops in commercial and experimental greenhouses were treated under different selection strategies: insecticide rotation versus formetanate reiteration, formetanate reiteration versus acrinathrin reiteration, and formetanate reiteration versus methiocarb reiteration. Thrips populations were sampled monthly and bioassayed against methiocarb, methamidophos, acrinathrin, endosulfan, deltamethrin and formetanate. In the laboratory, F occidentalis strains were selected against each insecticide for several generations. To evaluate cross-resistance, each selected strain was bioassayed with the other insecticides. Frankliniella occidentalis populations showed a rapid development of acrinathrin resistance, reaching high levels in field and laboratory conditions. Formetanate and methiocarb resistance were also observed, although development was slower and at moderate levels. Cross-resistances between acrinathrin/deltamethrin and acrinathrin/formetanate were detected under field and laboratory conditions. Formetanate/methiocarb cross-resistance was suspected in laboratory selections, but not in field assays. Simultaneous moderate resistance levels to the three specific insecticides against thrips (formetanate, methiocarb and acrinathrin) were shown in laboratory selection strains, indicating a general mechanism of resistance, probably metabolic. 相似文献
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Yuri Zharikov David B. Lank Falk Huettmann Russell W. Bradley Nadine Parker Peggy P. -W. Yen Laura A. Mcfarlane-Tranquilla Fred Cooke 《Landscape Ecology》2006,21(1):107-120
We studied habitat selection and breeding success in marked populations of a protected seabird (family Alcidae), the marbled
murrelet (Brachyramphus marmoratus), in a relatively intact and a heavily logged old-growth forest landscape in south-western Canada. Murrelets used old-growth
fragments either proportionately to their size frequency distribution (intact) or they tended to nest in disproportionately
smaller fragments (logged). Multiple regression modelling showed that murrelet distribution could be explained by proximity
of nests to landscape features producing biotic and abiotic edge effects. Streams, steeper slopes and lower elevations were
selected in both landscapes, probably due to good nesting habitat conditions and easier access to nest sites. In the logged
landscape, the murrelets nested closer to recent clearcuts than would be expected. Proximity to the ocean was favoured in
the intact area. The models of habitat selection had satisfactory discriminatory ability in both landscapes. Breeding success
(probability of nest survival to the middle of the chick rearing period), inferred from nest attendance patterns by radio-tagged
parents, was modelled in the logged landscape. Survivorship was greater in areas with recent clearcuts and lower in areas
with much regrowth, i.e. it was positively correlated with recent habitat fragmentation. We conclude that marbled murrelets
can successfully breed in old-growth forests fragmented by logging. 相似文献