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1.
Temporomandibular dysplasia was found in six American Cocker Spaniels related to each other. Clinical signs and diagnosis are described. 相似文献
2.
H. H. HOPPE 《Weed Research》1980,20(6):371-376
Effect of diclofop-methyl on the growth und development of Zea mays L. seedlings Diclofop-mcthyl, a diphenoxypropionic acid herbicide, had no effect on the germination of maize (Zea mays) seed. Prc-ger-minated maize embryos showed inhibited radicle growth when treated with the herbicide, but those of beans were considerably less sensitive. The inhibitory effect of the herbicide on maize radicle growth was reversed when the embryos were transferred to herbicide-free medium within 24 h of treatment. The higher concentrations of diclofop-methyl tested (≥10?6 M) induced necrosis on the second day of treatment, which first appeared in the meristematic and elongation zone of the root tip and then via the rest of the root to the grain. The herbicide increased the fresh and dry weight as well as the dry matter content of the radicle tips of Zea mays. These effects were attributed in an accumulation of cell wall material in the herbicide-treated root lips. In the presence of hydroxyurea, a selective inhibitor of cell division, the effect of diclofop-melhyl on radicle elongation was reduced but did not cease complelely. From these results it can be concluded that diclofop-methyl interferes with the processes that effect both cell division and cell elongation. 相似文献
3.
4.
FREDRIK E. HOPPE DVM PHD DAVE A. HAGER DVM PAUL W. POULOS JR. DVM PHD STINA EKMAN DVM P. G. LINDGREN MD PHD 《Veterinary radiology & ultrasound》1986,27(4):99-101
A manual, ultrasound-guided biopsy technique was compared to a new automatic method using a new biopsy device. The liver and the left kidney of 10 dogs were biopsied using the two methods. The specimens from the biopsies were compared for size and quality. Results demonstrate that larger and higher quality samples were obtained with the new automatic method. 相似文献
5.
NARUEPON KAMPA PETER LORD ENN MARIPUU ASTRID HOPPE 《Veterinary radiology & ultrasound》2007,48(6):585-593
Glomerular filtration rate (GFR) normalized to body fluid volumes to adjust for differing body size and conformation is more physiologically correct than a relationship with body weight (BW). GFR can be normalized to plasma volume by a renographic method that uses the Rutland-Patlak plot with plasma activity and kidney activity inputs. A plasma time-activity curve is obtained from a region of interest (ROI) of the left ventricle (LV), the size of which is in theory not critical. The aims of the study were to evaluate the effect of different LV ROI sizes, the effect of extravascular activity in the thorax over the LV ROI, and different time intervals for the semilogarithmic LV plot. Seventy-two scintigrams were used, with three different-sized automatic and a manual LV ROI, all with and without subtracting extravascular activity, and with LV curve time intervals of 30-120 s and 60-240 s. GFR/plasma volume was not affected by LV ROI sizes but significantly affected by extravascular activity subtraction and different time intervals. Subtracting extravascular activity from the LV ROI did not improve precision, but increased variability caused by different LV ROI sizes and time intervals chosen for the LV plot. The ROI for measuring extravascular activity apparently contained a considerable and variable intravascular component, which when subtracted, created noisy and unreliable LV curves. Manual LV ROI, without extravascular subtraction, and a time interval for LV input between 1 and 4 min are recommended as they gave the least variability determined by statistical analysis. With these methods, normal individual GFR/plasma volume in normal beagle dogs was 29.2 +/- 6.5 ml/min/l. 相似文献
6.
The relationships between plant and soil systems were investigated using multivariate statistical methods and relative ionic impulsions. Soil samples were taken from three locations and wild plant species consisted of:Poa, Pteridium aquilinum, Diplotaxis, Plantago lanceolata andTrifolium repens. The content of Mg, Ca, Na, K, Mn, Fe, Pb, Co, Ni, Cu, Zn and Cr in soils and plants was determined. A five-step chemical fractionation procedure (speciation) was applied to soil samples. Total metal contents were determined and amounts extracted with HCl, EDTA and DTPA were measured. Pb, Co, Ni, Cu, Fe, Zn, Cd and Cr in soils (considered as microconstituents for plants) show a greater number of statistically significant relationships with plant contents than those shown by macroconstituents (Mg, Ca, Na, K and Mn). On the other hand, only Zn and Pb extracted with EDTA and DTPA seem to be related to metal contents in wild plants. When using relative ionic impulsions, any soil fraction (obtained from the fractionation procedure, including the soluble fraction, which is the sum of all the fractions except the residual) is suitable for the study of soil-plant system, suggesting a global balance among all the fractions. Our results suggested an active assimilation for K and a passive uptake for Na, Ca and Mn. Furthermore, Fe seemed to favour the active assimilation of the other microelements. 相似文献
7.
A. HOPPE T. DENNEBERG† A. FRANK‡ B. KÅGEDAL§ L. R. PETERSSON‡ 《Journal of veterinary pharmacology and therapeutics》1993,16(1):93-102
Urinary excretion of nietals during treatment with 2-rnercaptopropioiiylglycine (2-MPG) was studied in 11 normal and 20 cystinuric male dogs. 'Ihe results
were compared with those obtained during D-penicillamine treatment.
Twenty-four-h urine and morning samples of urine were taken for determina-
tion of 13 metals before and during treatment. After single intravenous and oral
D-penicillamine treatment of the normal dogs, significant increases were found
in the 24-11 urinary excretion of Ca, Cu and Zn. Oral intake of D-penicillamine
increased the excretion of Ch, Cr, Fe and Mg as well. No effect on renal metal
excretion was observed after single intravenous and up to 2 months of daily oral
treatment with 2-MPG.
In 14 cystinuric dogs no effect was found after single intravenous and oral
administrations of 2-MPG. However, after oral treatment of six cystinuric dogs
with 2-MPG for 2–4 months, significantly increased excretions of Ca and Mg
were found. Fourteen of the cystinuric dogs were also investigated after 2–6
years of continuous 2-MPG treatment, and after this period no significant
elevation in the urinary excretion of metals was found. The present study shows
that in contrast to D-penicillamine, 2-MPG does not increase the urinary
excretion of metals to any appreciable extent. Observed increases in the
excretion of Ca and Mg seemed to be a temporary effect only. 相似文献
were compared with those obtained during D-penicillamine treatment.
Twenty-four-h urine and morning samples of urine were taken for determina-
tion of 13 metals before and during treatment. After single intravenous and oral
D-penicillamine treatment of the normal dogs, significant increases were found
in the 24-11 urinary excretion of Ca, Cu and Zn. Oral intake of D-penicillamine
increased the excretion of Ch, Cr, Fe and Mg as well. No effect on renal metal
excretion was observed after single intravenous and up to 2 months of daily oral
treatment with 2-MPG.
In 14 cystinuric dogs no effect was found after single intravenous and oral
administrations of 2-MPG. However, after oral treatment of six cystinuric dogs
with 2-MPG for 2–4 months, significantly increased excretions of Ca and Mg
were found. Fourteen of the cystinuric dogs were also investigated after 2–6
years of continuous 2-MPG treatment, and after this period no significant
elevation in the urinary excretion of metals was found. The present study shows
that in contrast to D-penicillamine, 2-MPG does not increase the urinary
excretion of metals to any appreciable extent. Observed increases in the
excretion of Ca and Mg seemed to be a temporary effect only. 相似文献
8.
K. DABROWSKI K. MATUSIEWICZ M. MATUSIEWICZ P. P. HOPPE J. EBELING 《Aquaculture Nutrition》1996,2(1):3-10
The relative bioavailability of ascorbic acid (AA) from several sources was compared in juvenile rainbow trout, Oncorhynchus mykiss (Walbaum). Fingerling trout were offered AA, and equimolar amounts of ascorbyl monophosphate Ca salt (CaAMP) or ascorbyl monophosphate-K, Mg salt (K/MgAMP) at graded levels of 20, 40, 80 and 320 mg kg?1. A control group was fed the same formula diet devoid of AA. During the 12 week long experiment, dietary concentrations of CaAMP and K/MgAMP remained unchanged while AA concentration decreased by 62.5%. No significant growth differences were found over a 12 week growout period, during which body weights increased 8–9 fold. No mortality or acute scurvy signs were observed in fish. Lysozyme activities tended to decrease in fingerlings supplemented with the highest AA level from all sources, although the difference was significant only in the case of the CaAMP diets. Blood plasma alkaline phosphatase showed no significant differences between treatments. However, phosphatase activity toward ascorbyl monophosphate (AMP) extracted from the intestine showed a gradual increase as the dietary AMP source was increased from 20 to 80 mg kg?1. Significant differences were found in AA concentration in the liver after 3 weeks of feeding graded levels of different sources of ascorbic acid. The differences in tissue AA concentrations among groups fed different dietary supplements increased with the duration of feeding. The bioavailability of AA and AA esters as measured by AA concentrations in the liver, kidney, intestine and blood plasma were equal. Despite the decrease in AA concentration in feeds supplemented with unprotected ascorbic acid after several weeks of storage, relationships between concentrations of ascorbic acid in the liver and those actually measured in feeds were not significantly different between treatments. 相似文献
9.
The progress of infection by high- and low-virulence isolates of Mycosphaerella pinodes was examined in susceptible and partially resistant pea leaves. Conidia germinated with one or more germ tubes which frequently branched and formed appressorium-like structures on the leaf surface. Penetration occurred through the epidermal walls. A structure similar to an infection vesicle was formed, lying partly in the epidermal wail and partly in the cell lumen. From this structure, a penetration hypha was derived which initiated the development of the intra- and intercellularly-growing fungal colony. Infections led to rapid tissue collapse in both susceptible and resistant interactions. In resistant interactions, the formation of infection vesicles and penetration hyphae was reduced, and the development and spread of lesions was retarded. 相似文献
10.
Reasons for performing study: Post operative ileus (POI) in horses is a severe complication after colic surgery. A commonly used prokinetic drug is lidocaine, which has been shown to have stimulatory effects on intestinal motility. The cellular mechanisms through which lidocaine affects smooth muscle activity are not yet known. Objectives: To examine the effects of lidocaine on smooth muscle in vitro and identify mechanisms by which it may affect the contractility of intestinal smooth muscle. Hypothesis: Ischaemia and reperfusion associated with intestinal strangulation can cause smooth muscle injury. Consequently, muscle cell functionality and contractile performance is decreased. Lidocaine can improve basic cell functions and thereby muscle cell contractility especially in ischaemia‐reperfusion‐challenged smooth muscle. Methods: To examine the effects of lidocaine on smooth muscle function directly, isometric force performance was measured in vitro in noninjured and in vivo ischaemia‐reperfusion injured smooth muscle tissues. Dose‐dependent response of lidocaine was measured in both samples. To assess membrane permeability as a marker of basic cell function, release of creatine kinase (CK) was measured by in vitro incubations. Results: Lidocaine‐stimulated contractility of ischaemia‐reperfusion injured smooth muscle was more pronounced than that of noninjured smooth muscle. A 3‐phasic dose‐dependency was observed with an initial recovery of contractility especially in ischaemia‐reperfusion injured smooth muscle followed by a plateau phase where contractility was maintained over a broad concentration range. CK release was decreased by lidocaine. Conclusion: Lidocaine may improve smooth muscle contractility and basic cell function by cellular repair mechanisms which are still unknown. Improving contractility of smooth muscle after ischaemia‐reperfusion injury is essential in recovery of propulsive intestinal motility. Potential relevance: Characterisation of the cellular mechanisms of effects of lidocaine, especially on ischaemia‐reperfusion injured smooth muscle, may lead to improved treatment strategies for horses with POI. 相似文献