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1.
An Abattoir Survey on the Frequency of Fatty Liver Syndrome in Dairy Cows from the Suburbs of Tehran
One hundred and six Holstein and Holstein x native cows were inspected before and after slaughter, and liver samples were taken. The fat content of all the liver samples was estimated by an extraction method (Soxhlet). The livers of 29 cows (27%) were classified as fatty. Seventeen of the animals were newly calved, 47 were non-pregnant, 33 were pregnant and 9 were dry, the median values for the fat content of their livers being 60.6, 34.4, 34.7 and 33.8 mg/g, respectively. The median concentration of liver fat in the first group was significantly different from that in each of the other groups (p < 0.01). 相似文献
2.
Afshin Raoofi DVM DVSc Seyed Hossein Mardjanmehr DVM PhD Majid Masoudifard DVM DVSc Farajollah Adibhashemi DVM DVSc Peyman Asadian DVM PhD 《Journal of Equine Veterinary Science》2006,26(12):588-591
A 4-year-old crossbred Thoroughbred mare was referred to the University of Tehran Veterinary Medical Teaching Hospital for evaluation of a mass in the pelvic cavity. The mare had been partially anorectic and pyrexic. On clinical examination, the mare was thin and depressed, with body temperature of 38°C, a pulse rate of 38 beats/minute, and a respiratory rate of 10 breaths/minute. Palpation per rectum revealed a large, smooth and tense mass in the anterior part of the pelvic cavity. Ultrasound examination confirmed the presence of a soft tissue mass with a thick wall. The inner surface of the mass had a villous-like appearance. The stroma of the mass was mottled, with accumulation of speckled and hypoechoic to slightly hyperechoic fluid. Hormone assays revealed low serum concentration of testosterone. Serum progesterone concentration indicated that active luteal tissue and serum estradiol concentration was 24 pg/ml. On histological examination, the sections from the tumor were composed of oval- or spindle-shaped cells loosely arranged in diffuse sheets or irregularly interlacing fascicles. On the basis of these histological findings, the large tumor mass of the left ovary was considered to be a thecoma. To our knowledge, the details of the clinical, ultrasonographic, endocrinologic, and histologic findings of this tumor in the mare have not been described in the veterinary literature. 相似文献
3.
Lohakare JD van de Sand H Gerlach K Hosseini A Mielenz M Sauerwein H Pries M Südekum KH 《Journal of animal physiology and animal nutrition》2012,96(1):25-36
This study elucidated the effects of limited concentrate feeding on growth, nutrient digestibility, blood profile and gene expression of gluconeogenic enzymes in the liver of dairy calves. The study utilized 36 German Holstein dairy calves (5-7 days of age) divided into two groups of 18 calves each for 150 days. Control group calves received 2 kg/(calf × day) of concentrate, whereas calves in the restricted group received only 1 kg/(calf × day). Good quality forage (mixture of maize and grass silages) was available for ad libitum consumption to both groups. The intake of milk replacer before weaning, and of concentrate were recorded daily per calf; however, the consumption of forages was quantified as daily average of the group. Body weights (BW) were recorded at start and on days 35, 70, 112 and 150. Blood and serum samples and spot urinary and faecal samples were also collected at similar time points. On days 70 and 150, liver biopsies were collected from seven animals in each group. The BW was not different between the groups at all times. Total BW gain in the control group was 124 kg as opposed to 111 kg in restricted group that led to average BW gain of 827 g/day and 739 g/day in respective groups, and the differences were significant (p = 0.018). As planned, the control group had higher concentrate and lower forage intake than the restricted group. The blood haemoglobin, haematocrit and serum variables (glucose, total protein, albumin and urea) were within the normal range in both groups, but serum glucose was higher (p < 0.05) in control than in restricted group at 70 days. There was no difference between groups in organic matter (OM) digestibility which declined (p < 0.001) with increasing age in both groups. Microbial crude protein (MCP) synthesis estimated from urinary allantoin excretion increased (p < 0.001) in both groups with increasing age but was not different between groups. The mRNA expressions for the gluconeogenic enzymes, cytosolic and mitochondrial phosphoenol pyruvate carboxykinase (EC 4.1.1.32) and pyruvate carboxylase (EC 6.4.1.1) measured by quantitative real-time PCR in liver biopsies showed no differences between groups. Overall, restricting concentrate moderately reduced the growth intensity without affecting the normal serum and blood indices, and MCP synthesis and OM digestibility showed no differences between groups, indicating that both concentrate feeding schemes can be successfully applied. 相似文献
4.
Adipose tissue expresses adipokines, which are involved in regulation of energy expenditure, lipid metabolism, and insulin sensitivity. To adapt for the transition from pregnancy to lactation, particularly in high-yielding dairy cows, adipokines, their receptors, and particular G-protein coupled receptors (GPRs) are of potential importance. Signaling by GPR 41 stimulates leptin release via activation by short-chain fatty acids; GPR 43/109A inhibits lipolysis, and GPR 109A thereby mediates the lipid-lowering effects of nicotinic acid and β–hydroxybutyrate. The aim of this study was to compare the mRNA expression of adiponectin and visfatin, adiponectin receptors 1 and 2 (AdipoR1/2), leptin receptor (obRb), insulin receptor as of the aforementioned GPRs during the transition period in high-yielding dairy cows. Biopsies from subcutaneous fat and blood samples were obtained from 10 dairy cows 1 week before and 3 weeks after calving. For AdipoR1 and AdipoR2 mRNA abundance as well as for leptin concentrations in plasma, a reduction (P ≤ .05) was observed postpartum; for visfatin and putative GPR 109A mRNA abundance in adipose tissue, there was a trend (P < .1) for analogous changes. In contrast, the mRNA content of obRb and GPR 41 in adipose tissue was higher (P ≤ .05) in samples from early lactation than in those from late gestation. Our results indicate decreasing adiponectin sensitivity in adipose tissue after calving, which might be involved in the reduced insulin sensitivity of adipose tissue during early lactation. In addition, visfatin, GPR 41, and GPR 109A may further modulate insulin sensitivity. 相似文献
5.
A simple model for chickpea development, growth and yield 总被引：1，自引：0，他引：1
Chickpea (Cicer arietinum L.) yield is unstable and low in major producer countries. A robust crop model can assist in evaluation of possible genetic improvements and cultural management practices to improve yield. The objectives of this study were to develop and test a chickpea simulation model that could be used across a wide range of environments. This model simulates phenological development, leaf development and senescence, mass partitioning, plant nitrogen balance, yield formation and soil water balance. Responses of crop processes to environmental factors of solar radiation, photoperiod, temperature, nitrogen and water availability, and genotype differences were included in the model. The model uses a daily time step and readily available weather and soil information. The model was tested using independent data from a wide range of growth and environmental conditions. In most cases, simulated grain yield were similar to observed yield (ranging from 20 to 379 g m−2) with a root mean square root of 26 g m−2 (15% of average measured yield). It was concluded that the model generality, i.e., constant parameters for genotypes across locations, and applicability to a wide range of environmental conditions factors made this model especially useful. 相似文献
6.
Afshin Raoofi Farhid Hemmatzadeh Amir Mansoor Ghanaei 《Tropical animal health and production》2010,42(3):411-414
This serological survey was carried out to detect antibodies in dromedary camels against BVD virus in Iran. A total of 137
serum samples, were collected from camels at Khorein abattoir in suburbs of Tehran and examined for BVDV, using the serum
neutralization test (SNT). Twenty seven of the 137 camels (19.7%) were positive for BVDV antibodies. It was found that the
rate of seropositive camels in Iran is substantially higher compared to figures published in most other countries. This study
indicated an increased frequency of infection rate with increasing age of camels. The frequency of positive cases was not
significantly different between male and female camels. 相似文献
7.
Effects of largely different feeding intensities on serum insulin‐like growth factor‐1 concentrations,quantified by enzyme immunoassay,leptin and growth hormone receptor 1 mRNA in rainbow trout (Oncorhynchus mykiss) 
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下载免费PDF全文 B. Pfundt B. Mielenz F. Sanver E. Pfeffer H. Sauerwein M. Mielenz 《Aquaculture Nutrition》2016,22(3):586-596
Insulin‐like growth factor‐1 (IGF‐1), somatolactin and leptin are involved in growth regulation and energy metabolism in fish. We herein focused on serum IGF‐1 concentration analysed by enzyme‐linked immunosorbent assay in restrictively fed rainbow trout (Oncorhynchus mykiss). The animals were fed a high‐fat/low‐protein diet at daily feed increases (DFI) ranging from 0.5% to 2% of initial body weight (IBW), starting either at 62 or 176 g IBW. In selected groups, growth hormone receptor 1 (GHR1) and leptin mRNA were quantified in liver, and GHR1 mRNA also in visceral adipose tissue. Serum IGF‐1 concentrations in both IBW groups were highest at 2% and 1% DFI and were nonlinearly decreasing with reduced DFI. The low‐IBW groups had mostly lower IGF‐1 concentrations than the high‐IBW groups. Leptin and GHR1 mRNA decreased with feeding intensity in liver, but GHR1 mRNA increased in adipose tissue. IGF‐1 is related to growth and may help to mitigate oxidative stress in consequence of lipid mobilization during restrictive feeding. IGF‐1 secretion associated with stress response in addition to its function in growth and energy metabolism seemed to reach a point of inflection at DFI 1%. Leptin and GHR1 might be linked to lipid metabolism and free fatty acid partitioning towards liver. 相似文献
8.
Baradari AG Zeydi AE Aarabi M Ghafari R 《Pakistan journal of biological sciences: PJBS》2011,14(23):1047-1054
Perioperative hyperglycemia is common in patients with type 2 diabetes undergoing Coronary Artery Bypass Graft (CABG) surgery and there is a direct relation between postoperative hyperglycemia and mortality rate in these patients. The aim of the present study is to determine the efficacy of metformin on glycemic control in diabetic patients after CABG surgery. In a randomized double blind clinical trial, 100 patients with type 2 diabetes admitted in open heart ICU after CABG surgery in Mazandaran Heart Center were enrolled. They were randomly assigned to two intervention and control groups. Three hours after extubation, therapeutic antiglycemic regimens were applied in these two groups and continued for three days. Intervention group received regular insulin infusion along with two metformin 500 mg tablets per twelve hours while control group received regular insulin infusion with two placebo tablets per twelve hours. Blood glucose level and other parameters were measured and recorded in determined intervals. To analyze the data, independent T-test, paired T-test, Mann-Whitney and repeated measure ANOVA tests were employed. Mean blood glucose level was not significantly different in the two groups at the beginning of the ICU admission; however, mean glucose level in insulin-metformin group, twelve hours after the initiation of the study, was significantly lower than insulin group (p < 0.05). In addition, mean doses of potassium and insulin demand as well as mean number of episodes of hyperglycemia, hypoglycemia and glucose levels out of the accepted range were significantly lower in insulin-metformin group (p < 0.05). Alterations in mean levels of lactate, BE, pH and creatinine were not statistically significant in these two groups. It seems that adding metformin to insulin leads to a better glycemic control in type two diabetic patients undergoing CABG surgery without causing metabolic acidosis. Therefore, it might be a potential option in blood glucose control protocol in this group of patients. 相似文献
9.
Hosseini Lida Maleki Abbas Mozafari Afshin Mirzaeiheydari Mohammad Sadeghi-Shoae Mehdi 《Gesunde Pflanzen》2022,74(1):177-191
The aim of this study was to evaluate the water and nitrogen use efficiency and some quantitative and qualitative characteristics of forage beet cultivars under the influence of different irrigation methods and nitrogen levels in two cropping years, 2017–18 and 2018–19, at Agricultural Research Station in Karaj, Iran. Experimental factors included the first factor with four irrigation methods (normal leakage, alternate furrow irrigation, fixed furrow irrigation, type (drip-strip)), the second factor was the amount of nitrogen fertilizer with three levels (150, 200 and 250?kg N ha?1) and the third factor included three forage beet cultivars (Sbsi052, Jamon and Kyros). Among irrigation treatments, alternate furrow irrigation and fixed furrow irrigation had the highest sugar content with 9.28% and 9.17%, respectively. The highest yield of digestible organic matter was obtained in leakage irrigation treatment, nitrogen fertilizer of 250?kg ha?1 and in Kyros at the rate of 19.45?t ha?1. The highest yield of root digestible dry matter, potassium, sodium and free nitrogen was observed in leakage irrigation treatment and consumption of 200?kg ha?1 nitrogen was observed in foreign cultivars. The highest crude protein was observed in alternate furrow irrigation conditions with a consumption of 200?kg ha?1 nitrogen in cultivar Sbsi052 at 13.08%. Leakage irrigation and type tape had the highest consumption efficiency and efficiency of nitrogen uptake with application of 150 and 200?kg ha?1 N, and the highest water use efficiency was also observed in leakage irrigation and type tape with application of 250?kg ha?1 N in domestic and foreign cultivars. The type irrigation method showed better quantitative and qualitative yield than the furrow irrigation methods.
相似文献10.
Androgen and estrogen receptors in bovine skeletal muscle: relation to steroid-induced allometric muscle growth 总被引：2，自引：0，他引：2
The presence of free androgen (AR) and estrogen receptors (ER) was demonstrated in bovine skeletal muscle. Androgen receptor concentrations in neck muscle from cattle of different sexes and stages of development were related to hormonal status. In mature bulls (mean weight 600 kg), no free AR was detectable. Highest AR concentrations were measured in mature bulls (517 kg) castrated 24 h prior to slaughter (.85 +/- .21 fmol/mg protein). In female calves (155 kg), AR concentrations (.56 +/- .14 fmol/mg) were greater (P less than .01) than in male calves (.20 +/- .08 fmol/mg) of the same weight. Androgen receptors and ER in skeletal muscle of neck, shoulder, abdomen and hind leg of female and male calves were compared. There was no significant difference between AR concentrations in the neck, shoulder and hind leg, but concentrations were lower (P less than .05) in abdominal muscle. Estrogen receptor concentrations in neck, shoulder, abdomen and hind leg were not different between sexes (P less than .05). In male calves, ER content was lower (P less than .05) in abdominal than in other muscles. Estrogen receptor concentrations in muscles of female calves did not differ (P less than .05). The pronounced sensitivity to estrogens and androgens in the neck, shoulder, and hind leg of calves, being free of the respective hormone, may partly explain the characteristic conformation in calves treated with estrogenic and androgenic steroids and the sexual dimorphism of muscle growth. 相似文献