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The majority of sows return to estrus within 2 weeks after weaning. Swine practitioners attempt to optimize production by reducing the WEI. Some sows fail to resume estrous cyclicity after weaning; however, the endocrinologic pathogenesis of these anestrous sows is speculative. The average WEI is influenced by numerous factors, including season, environmental temperature, photoperiod, nutrition, stress, facility design, lactation length, and management practices. It is evident that the majority of these factors have a more profound influence on primiparous sows than on multiparous sows. Optimum protein and energy consumption by sows during lactation and after weaning and effective utilization of breeding facilities reduce the WEI. The precise roles of photoperiodic changes, elevated environmental temperatures, and stress in seasonal infertility remain poorly understood. Fortunately, current management techniques have reduced the WEI on most farms without instituting therapeutic measures.  相似文献   
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This study was designed to determine the long-term effects of repeated endotoxin treatment or immunization against human serum albumin on concentrations of serum insulin-like growth factor-I (IGF-I) and other indicators of growth performance in growing pigs. Thirty gilts (38.5 +/- 0.9 kg) were randomly assigned to 5 treatment groups (n = 6 animals/group): 1) lipopolysaccharide injections, 2) lipopolysaccharide pair-fed, 3) human serum albumin immunization, 4) human serum albumin pair-fed, and 5) control. Pigs in the lipopolysaccharide group were treated intramuscularly with lipopolysaccharide on Days 0-3. The pigs in the human serum albumin group were immunized with human serum albumin emulsified in Freund's adjuvant on Day 0 and administered a booster on Day 28. The lipopolysaccharide pair-fed pigs were matched by body weight and pair-wise fed with pigs treated with lipopolysaccharide. Similarly, human serum albumin pair-fed pigs were matched to human serum albumin immunized pigs. Serum IGF-I concentrations did not differ between or within groups. There was no difference in feed disappearance between groups prior to the initiation of treatments. The lipopolysaccharide group had a decrease (P = 0.013) in feed disappearance on Day 0 compared with control and human serum albumin groups. On Day 1, both lipopolysaccharide and human serum albumin groups differed (P < 0.05) from control. Average daily gain and total weight gain did not differ between groups; however, feed efficiency differed (P < 0.05) between lipopolysaccharide and control groups. Long-term effects of repeated endotoxin challenge or immunization on IGF-I concentrations and growth were not evident in the present study. This failure presumably was due to the development of endotoxin tolerance and a relatively innocuous vaccination against human serum albumin.  相似文献   
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Horses with undescended testes are frequently presented to the veterinary surgeon for castration. The pertinent pre-operative evaluations and diagnostic procedures that should be made prior to either surgical intervention or referral of such cases are outlined. Several accepted anesthetic and surgical techniques are similarly reviewed. Case histories of 58 horses referred during a two year period are reviewed and correlated with the findings of a recent study of equine testicular development and descent.  相似文献   
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Endocrine changes in sows with ovarian cysts were determined to be comparable with those in sows in diestrus. Blood samples were collected at frequent intervals from 5 sows affected with cystic ovaries. Concentrations of serum luteinizing hormone, progesterone, estradiol-17 beta, and cortisol were determined by use of established radioimmunoassays. The development of ovarian cysts has been proposed to be associated with a deficiency of luteinizing hormone rather than an intrinsic ovarian abnormality. In contrast, the results of this study demonstrated that tonic and pulsatile luteinizing hormone release were not affected adversely in sows with cystic ovaries.  相似文献   
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An 18-week study was conducted to evaluate orthotopic osteochondral transplantation of the proximal femur in the dog. Eighteen dogs were divided into 3 groups of 6 each. The first group received autografts, the second received fresh allografts, and the third received grafts that had been frozen in a bone bank for 24–28 days. The grafts were fixed in position using dynamic compression plates. The grafted limbs were maintained in a sling and thus were nonfunctional and non-weight bearing throughout the 18-week study. Postoperatively the dogs were given oral tetracycline to assess osteo- cyte viability. The dogs were radiographed at 2–week intervals and 1 dog in each group was euthanatized every 3 weeks. The femurs were examined using standard histopathologic and fluorescent labeling techniques. All femoral heads were luxated by the 2nd postoperative week. The bones of all the femoral heads underwent avascular necrosis and degenerative changes were present in the transplanted cartilage by the 6th postoperative week. During the first 18 weeks following transplantation there was little radiographic and histologic difference among the 3 types of grafts regarding the nature and rate of bone healing. Based on the data obtained from techniques utilized in this study, the femoral head, neck, and articular cartilage did not survive, while the femoral diaphysis did survive the transplantation process. Different techniques may alter to some degree the results obtained.  相似文献   
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Testosterone concentrations in stallions showed a seasonal trend with peak concentrations in the spring (April and May in Britain) and lowest concentrations in the period from December to February. The effect on this pattern of changing the length of the photoperiod at the end of the normal breeding season (mid-summer's day) was studied in 2 experiments. In the first experiment artificial illumination was organised from 21 June to mimic the effect of transfer to a southern hemisphere spring and summer, that is short days becoming longer. The stallions had low concentrations of testosterone in February and high concentrations in April. Concentrations in July, August and September were extremely low with a return to high values in late November/early December. In the second experiment, illumination was maintained at the equivalent of a 16 1/2-hour day from 21 June to mid December. These stallions had high testosterone concentrations in April, after which they fell until August, later rising to a maximum in October. These results are discussed in relation to transfer of stallions between the northern and southern hemispheres.  相似文献   
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The Cloward technique for intervertebral fusion was utilized on 12 horses ranging from 3 months to 2 years of age. Of the 12 horses, 9 had been diagnosed as having equine cervical vertebral malformation (CVM) or "wobbles," and 3 were normal controls. A large hole was drilled from the ventral border of the vertebral bodies spanning the intervertebral disc and the vertebral end plates of the 2 articulating vertebrae. Frozen homologous bone dowels of slightly larger diameter from equine cadaver ilia were inserted in the holes. No adverse postoperative complication arose. Clinical improvement was seen in all horses with CVM. Three months postoperatively, partial or complete fusion was evident radiographically in 11 of the 12 horses. Necropsies were performed 3–6 months postoperatively to evaluate the quality of the fusion. Cadaver manipulation demonstrated reduced intervertebral movement at the operative site in all cases. The articulations of the equine cervical spine can be operatively fused by the Cloward technique, and surgically induced trauma is minimal. This technique can be used for stabilizing subluxations and may be applicable for treating fractures and osteolytic processes that have weakened vertebrae.  相似文献   
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