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1.
Anneleen Watteyn Heidi Wyns Elke Plessers Elisa Russo Siegrid De Baere Patrick De Backer Siska Croubels 《Veterinary journal (London, England : 1997)》2013,195(2):216-220
The aim of this study was to determine the pharmacokinetics of dexamethasone in broiler chickens. Dexamethasone sodium phosphate (0.3 mg/kg bodyweight) was injected IV or IM and blood samples were collected at 0, 0.25, 0.5, 0.75, 1, 2, 4, 6, 8, 10, 12 and 24 h after administration. Dexamethasone in the plasma samples was measured using a liquid chromatography–tandem mass spectrometry method and the pharmacokinetics analysed according to a one-compartmental model.The maximum plasma concentration after IM administration occurred at 0.37 h. The elimination half-life for dexamethasone was 0.46 h and 0.70 h following IV and IM administration, respectively, which was shorter than other species, while the clearance (1.26 L/h kg) was higher than has been reported for other species (<0.5 L/h kg). The volume of distribution (～1 L/kg) was similar to values reported for other species and the bioavailability of dexamethasone after IM administration was 100%. The results from this study will be useful in investigating whether inflammatory disease may affect the pharmacokinetic parameters of dexamethasone in chickens. 相似文献
2.
Jingping Guo Anneleen Swanepoel Joo Reis Guillaume Salze Melanie Rhodes Donald Allen Davis 《Aquaculture Nutrition》2020,26(2):368-381
A series of growth, feed stability and consumption trials were conducted to evaluate the efficacy of salmon by‐product in practical diets for Pacific white shrimp, Litopenaeus vannamei. This included a salmon by‐product meal (Salmon meal: SM) and a silage hydrolysate (hydrolysed salmon meal: HSM). The basal diet containing 120 g/kg SM was incrementally replaced (0. 25, 50, 75, 100%) by HSM to produce five test diets used in two trials. A sixth diet was included which evaluated gelatin supplementation (trial 1) or pH neutralization (trial 2). In trial 1, each diet was produced using two processing conditions (laboratory extruded and formed with meat grinder) and offered to shrimp in a clear water system. The results demonstrate that up to 50% of the SM can be used to replace with HSM; however, further increases resulted in reduced performance of shrimp. The addition of gelatin reduced leaching but there was limited effect of processing on leaching. There were no detectible effects of pH adjustment of the diets. Results indicated that the growth performance of shrimp has not influenced by HSM up to 60 g/kg to replace 50% of the SM in practical diets; however, higher levels resulted in significant decrease in performance. 相似文献
3.
Inge M. Hanssen Anneleen Paeleman Lieve Wittemans Kris Goen Bart Lievens Claude Bragard Alfons C. R. C. Vanachter Bart P. H. J. Thomma 《European journal of plant pathology / European Foundation for Plant Pathology》2008,121(2):131-146
Over a period of a few years, Pepino mosaic virus (PepMV) has become one of the most important viral diseases in tomato production worldwide. Infection by PepMV can cause
a broad range of symptoms on tomato plants, often leading to significant financial losses. At present, five PepMV genotypes
(EU, LP, CH2, US1 and US2) have been described, three of which (EU, LP and US2) have been reported in Europe. Thus far, no
correlation has been found between different PepMV genotypes and the symptoms expressed in infected plants. In this paper,
the genetic diversity of the PepMV population in Belgian greenhouses is studied and related to symptom development in tomato
crops. A novel assay based on restriction fragment length polymorphism (RFLP) was developed to discriminate between the different
PepMV genotypes. Both RFLP and sequence analysis revealed the occurrence of two genotypes, the EU genotype and the CH2 genotype,
within tomato production in Belgium. Whereas no differences were observed in symptom expression between plants infected by
one of the two genotypes, co-infection with both genotypes resulted in more severe PepMV symptoms. Furthermore, our study
revealed that PepMV recombinants frequently occur in mixed infections under natural conditions. This may possibly result in
the generation of viral variants with increased aggressiveness. 相似文献
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Jingping Guo Anneleen Swanepoel Xuan Qiu Joo Reis Melanie Rhodes D. Allen Davis 《Aquaculture Nutrition》2020,26(2):490-501
A series of trials were conducted with Pacific white shrimp Litopenaeus vannamei, to evaluate the efficiency of two salmon meals as compared to anchovy meal. The basal diet contained 200 g/kg anchovy meal, which was systematically replaced (0%, 50%, 75% and 100%) with salmon meal on an isonitrogenous basis. Another two diets were formulated with a hydrolysed salmon meal to replace 50% and 100% anchovy meal. Each diet was randomly fed to four replicate groups of 25 and 30 shrimp per tank in clear (indoor) and green (outdoor) water trials, respectively. The results showed that growth performance and feed conversion ratio were not statistically different when salmon meal replaced anchovy meal in both trials. However, when hydrolysed salmon meal was used to replace 100% of the anchovy meal, growth performance of the shrimp significantly decreased. The four kinds of fish meal (anchovy, salmon by‐product meals and menhaden) were evaluated in an ingredient digestibility trial using the 70:30 replacement technique. In general, dry matter, energy, protein and individual amino acids digestibility of salmon meal were significantly higher than those of menhaden and anchovy meal. Results of this study demonstrated that salmon meals are a good protein sources which can replace anchovy meal. 相似文献
7.
Wheat puroindolines (PINs) spontaneously adsorb at air/water interfaces and show excellent foaming properties. They can positively impact bread quality, in which the formation of stable foam is important for product quality. The impact of endogenous PINs on bread quality was studied by preparing gluten–starch blends from isolated gluten and starch fractions with different PIN levels, which allowed largely retaining the interaction between PINs and flour components. Our results indicate that blends with high PIN levels yielded more homogeneous crumb structures with fine gas cells than bread made with blends containing medium or low PIN levels. However, the mechanism by which PINs exert this crumb improving effect is not clear. Varying PIN levels impacted neither dough extensibility nor did it result in different PIN levels in dough liquor. Lipid removal yielded bread with a less homogeneous crumb gas cell distribution, indicating that lipids also are required to obtain good crumb structure. 相似文献
8.
A. Stinckens T. Luyten K. Van den Maagdenberg S. Janssens S. De Smet M. Georges N. Buys 《Domestic animal endocrinology》2009,37(4):227-235
In the swine breeding industry, two economical traits are of particular importance in sires, namely, muscle growth and average daily gain (ADG). These traits are quantitative, which implies that they are under the control of multiple genes. Mutations in these genes, associated with either muscularity or growth, are useful quantitative trait nucleotides (QTN) for unraveling genetic variation of these traits and can be used in marker-assisted selection. Until now, QTN involved in muscle growth and/or ADG in pigs were identified in porcine ryanodine receptor 1 (RYR1), insulin-like growth factor-2 (IGF-2), and melanocortin-4 receptor (MC4R). Recently, a fourth possible QTN was found in porcine myostatin (MSTN). All four QTN have an influence on muscle growth and/or somatic growth, so an influence of one mutation on one or more of the other mutations should not be excluded. However, although the polymorphisms in the RYR1 and the MC4R gene affect the function of the respective protein, the polymorphisms of the IGF-2 and MSTN gene influence the mRNA expression of the respective gene. Therefore, this study investigated possible interactions between the genotypes of MSTN, IGF-2, and MC4R (population 1) or the RYR1, IGF-2, and MSTN QTN (population 2) on IGF-2 and MSTN expression in different muscle types in pigs. In both skeletal muscle and heart muscle growth, the IGF-2:MSTN ratio seems to play an important role. Also, the RYR1 genotype had a significant effect on IGF-2 expression in m. longissimus dorsi. No effect of the MC4R QTN could be seen. 相似文献
9.
Anneleen Pauly Bram PareytNiels De Brier Ellen FierensJan A. Delcour 《Journal of Cereal Science》2012
Wheat (Triticum aestivum L.) kernel hardness is a major quality characteristic, which has been ascribed to the presence of puroindolines a and b. These proteins occur in higher levels at the surface of water-washed starch granules from soft wheat cultivars than at that of starch from hard wheat cultivars. In the present study, prime starch was isolated from flour from soft wheat (cultivar Claire) using a dough ball or batter based separation method. Starch isolated with the dough ball method contained lower levels of puroindolines, as well as of other starch granule associated proteins and lipids than that isolated with the batter method. Similar patterns of puroindoline and lipid levels after starch isolation can presumably be related to (polar) lipid binding by puroindolines. Both isolated starch fractions showed comparable differential scanning calorimetry thermograms, whereas higher levels of starch surface associated components restricted starch swelling. Necessary controls demonstrated that the observed differences did not arise from artefacts associated with hydration, fractionation or freeze-drying in the experimental protocols. Apparently, proteins and lipids at the starch granule surface impact water absorption and, as such, starch swelling, but they do not affect starch granule internal phenomena such as melting of the crystalline amylopectin chains. 相似文献