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Marco Quartuccio Gabriele Marino Giuseppe Garufi Santo Cristarella Antonina Zangh�� 《Journal of veterinary science (Suw?n-si, Korea)》2012,13(2):207-209
The association of cryptorchidism, functional Sertoli cell tumors, and spermatic cord torsion has been rarely reported in the literature. Two dogs were admitted for bilateral skin alopecia and weight loss. Both animals were cryptorchid and displayed a pendulous preputial sheath, prostate hypertrophy, and increased levels of circulating oestrogen. Transabdominal palpation and ultrasonography revealed the presence of neoplastic retained gonads. During surgery, spermatic cord torsion was also detected in the enlarged neoplastic testes of both dogs. Histologic examination confirmed the presence of Sertoli cell tumors that were primarily responsible for the feminizing syndrome. Complete remission of all symptoms occurred within 3 months after orchiectomy. 相似文献
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Marco QuartuccioGabriele Marino BS PhD RU Antonina ZanghìGiuseppe Garufi DVM Santo Cristarella DVM PO 《Journal of Equine Veterinary Science》2011,31(3):143-146
A careful evaluation of daily sperm output (DSO) and seminal parameters is indicative of the potential fertility of the animal and at the same time is useful for maximization of the reproductive activity. The aim of this article was to evaluate the seminal parameters, testicular volume (TV) calculated by ultrasound measurements, DSO, and any eventual relationship between these in Ragusano donkey jackasses. Eight Ragusano donkey stallions underwent a morphometric evaluation of the testes by ultrasound to calculate the TV, and daily semen collection for 10 consecutive days. TV ranged from 250 to 500 cm3 and no significant differences could be observed between the left and right testes. Only ejaculates from 4 to 10 days were analyzed, given that there was evidence that the sperm extragonadal reserve interfered with the total number of sperm in ejaculates during the early days. DSO in the Ragusano donkey ranged from 7 to 23 × 109 sperms. The seminal parameters showed high values of motility, viability, and low abnormality percentages. Age, TVs, and sperm parameters were not significantly correlated. The correlation between TV and DSO was poor (P = .1) in this study and this may suggest that TV and DSO might simply not be highly correlated in the donkey. 相似文献
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Michela Pugliese Vito Biondi Annamaria Passantino Francesca Licitra Angela Alibrandi Antonina Zanghi Francesca Conte Gabriele Marino 《Animal Science Journal》2021,92(1):e13546
The present study aimed to compare the welfare of dairy cows kept in two traditional husbandry systems (semi-intensive and intensive farming) in south-eastern Sicily. A total of 18 dairy farms (nine semi-intensive and nine intensive) were evaluated with a multicriteria system adapted for Sicilian conditions and obtained simplifying the model of the European Food Safety Authority (EFSA). Values of welfare measures, collected by inspections of the farms (general well-being indicators, ventilation system, resting areas [cubicles or bedding], flooring, milking parlours and waiting area, manger and watering equipment), and those of health categories (cases of abortions, hypocalcemia, displacement of abomasum, acidosis/ketosis, enteritis, hoof problems, and mastitis) obtained through the farm records, were compared using Mann–Whitney and Chi-squared tests, respectively. Data showed significant differences (p ≤ .05) about the variables related to welfare categories such as housing ventilation system, resting area, manger, and water equipment that were better in the semi-intensive system than the intensive system. No significant differences were observed about the variables related to health indicators. The results demonstrated that in Sicily the semi-intensive farm is better than the intensive to satisfy the conditions of animal welfare. 相似文献
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Antonina Klimenko Robin Huber Laurence Marcourt Estelle Chardonnens Alexey Koval Yuri S. Khotimchenko Emerson Ferreira Queiroz Jean-Luc Wolfender Vladimir L. Katanaev 《Marine drugs》2021,19(1)
Triple-negative breast cancer (TNBC) represents the deadliest form of gynecological tumors currently lacking targeted therapies. The ethanol extract of the North Pacific brittle star Ophiura sarsii presented promising anti-TNBC activities. After elimination of the inert material, the active extract was submitted to a bioguided isolation approach using high-resolution semipreparative HPLC-UV, resulting in one-step isolation of an unusual porphyrin derivative possessing strong cytotoxic activity. HRMS and 2D NMR resulted in the structure elucidation of the compound as (3S,4S)-14-Ethyl-9-(hydroxymethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid. Never identified before in Ophiuroidea, porphyrins have found broad applications as photosensitizers in the anticancer photodynamic therapy. The simple isolation of a cytotoxic porphyrin from an abundant brittle star species we describe here may pave the way for novel natural-based developments of targeted anti-cancer therapies. 相似文献
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Yevheniya Nechiporuk Vitaliy Novak Antonina Melnychenko Olga Bevz Volodymyr Dudka 《Anatomia, histologia, embryologia》2020,49(6):830-835
Both cats and dogs belong to animals with the same type of limb support but have different nature of movement. Despite belonging to digitigrade animals, cats and dogs have a different nature of motion. While moving, the medial joint surface in cats and lateral surface in dogs carry the larger pressure. The aim of the study was to compare the similar surfaces of the cat's and dog's tarsal joint capsule and to detect differences in its histostructure and vascularisation. For the study, we used the capsule of the tarsal joint of five cats and five dogs dissected with accordance to anatomical surfaces. Sections of the capsule joint were stained with haematoxylin–eosin. The sections were examined with a microscope at magnification ×250 and ×400. The statistical analysis of the results was done using Student's t test. During the research, a difference in histostructure and vascularisation of tarsal joint capsule in cats and dogs on respective surfaces were found. The medial surface of the tarsal joint capsule was the most saturated with hemomicrocirculatory bed structures in cats, whereas this was the lateral surface in dogs. The most active metabolic processes also take place in these areas of the joint capsule, which is important to know when prescribing therapeutic procedures and determining an optimal surgical access. 相似文献
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植物叶片生物源挥发性有机化合物的排放量在生物化学和大气过程中起到了很重要的作用。生物源挥发性有机化合物的排放量可能涉及数量不同多种化合物,是一种重要的植物信号传导方法。然而,一些挥发性化合物的排放量可能对区域内的空气质量产生负面的影响。为了更好的了解生物源挥发性有机物在植物生理学和化学生态学中的作用,更好的预测这些排放量将如何改变空气质量,必须要了解这些不同的化合物之间的潜在的联系。过去,对不同植物的生物挥发量进行直接比较是很困难的,因为调查和测量往往集中于一类数量有限的化合物中,并且在对不同功能组别的化合物的分离和检测的分析技术也较为缺乏。此外,相关性强的树种通常会挥发出相类似的化合物,这是使植物本身和与其他植物发出的生物源挥发性有机化合物的排放量难以辨明的原因。 相似文献
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van Breugel M Hirono M Andreeva A Yanagisawa HA Yamaguchi S Nakazawa Y Morgner N Petrovich M Ebong IO Robinson CV Johnson CM Veprintsev D Zuber B 《Science (New York, N.Y.)》2011,331(6021):1196-1199
Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules strictly required to template cilia and flagella. The highly conserved protein SAS-6 constitutes the center of the cartwheel assembly that scaffolds centrioles early in their biogenesis. We determined the x-ray structure of the amino-terminal domain of SAS-6 from zebrafish, and we show that recombinant SAS-6 self-associates in vitro into assemblies that resemble cartwheel centers. Point mutations are consistent with the notion that centriole formation in vivo depends on the interactions that define the self-assemblies observed here. Thus, these interactions are probably essential to the structural organization of cartwheel centers. 相似文献
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