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The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors 总被引：34，自引：0，他引：34
S M Goyert E Ferrero W J Rettig A K Yenamandra F Obata M M Le Beau 《Science (New York, N.Y.)》1988,239(4839):497-500
CD14 is a myelomonocytic differentiation antigen expressed by monocytes, macrophages, and activated granulocytes and is detectable with the monoclonal antibodies MO2, MY4, and LeuM3. Analyses of complementary DNA and genomic clones of CD14 show that it has a novel structure and that it maps to chromosome 5 within a region containing other genes encoding growth factors and receptors; it may therefore represent a new receptor important for myeloid differentiation. In addition, the CD14 gene is included in the "critical" region that is frequently deleted in certain myeloid leukemias. 相似文献
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Comparison of Ni/Zn Accumulation Ability of Thlaspi japonicum from Three Different Areas in Hokkaido
Takafumi Mizuno Hitoshi Obata Kenji Horie Shiro Nosaka Naoharu Mizuno 《Soil Science and Plant Nutrition》2005,51(4):589-594
Thlaspi japonicum is a Japanese Ni-hyperaccumulator plant growing in areas with serpentine soil containing a high level of Ni. In the present study, we investigated the ability of wild Thlaspi japonicum plants inhabiting non-ultramafic soil areas of Hokkaido to accumulate Ni/Zn. Wild T. japonicum plants growing on Rebun Island (Rebun-T) accumulated small amounts of Ni, while the plants cultivated on ultramafic rock soil accumulated large amounts of Ni, like T. japonicum growing on Mt. Yubari (Yubari-T), and this change was also observed for T. japonicum growing on Mt. Tengu (Tengu-T). All the T. japonicum plants transplanted on both ultramaflc soil or Andosol accumulated over 100 mg kg−1 Zn, especially the Ni/Zn content of Tengu-T plants tended to be higher than that of the plants growing in the other two areas. In contrast, transplanting of Yubari-T plants from ultramafic soil with a high level of Ni to soil with a lower-Ni content decrease of the Ni concentration in the leaves. Wild Rebun-T plants showed a smaller biomass than the Yubari-T and Tengu-T plants, and some individuals of the Rebun-T population were smaller than those of the other populations, with tiny radical leaves. Zinc content of the small leaves was not significantly different from that in large leaves. These results suggested that T. japonicum plants are able to accumulate high Ni/Zn accumulation, regardless ecotype, habitat and leaf size. 相似文献
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Shigeru NINOMIYA Masato AOYAMA Yumiko UJIIE Ryo KUSUNOSE Atsutoshi KUWANO 《Journal of Equine Science》2008,19(3):53-56
The objective of this study was to investigate the effect of straw, sawdust, coconut husk
(husk), and coconut fiber (fiber) on the welfare of stable horses by observing their
resting behavior. Twenty horses with ages ranging from 3 to 21 years were used at the
Equine Research Institute of the Japan Racing Association, Utsunomiya, Japan. Five horses
were allocated to each bedding condition. The behavior of each horse was recorded by video
camera for 3 days and was continuously sampled from 17:00 to 05:00. The total duration,
the number of bouts, and the mean and the maximum duration of bouts in standing rest,
sternal lying, and lateral lying were calculated and analysed by the Kruskal-Wallis test
and post hoc Steel-Dwass test. There was no difference in the standing rest and the
sternal lying among beddings. Significant differences were observed in these values in the
lateral lying among the different beddings (P<0.05). The values of the means of the
total duration, the number of bouts, and the mean and the maximum duration of bout in the
lateral lying were greater when husk was used as the bedding material than when sawdust
were used (P<0.05). The results of the observations show that the new bedding materials
would be as usable as straw. However, lateral lying was observed less frequently when
sawdust were used as bedding; this indicates that use of sawdust as bedding material will
decrease the welfare of stabled horses. 相似文献
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To confirm ability forming the basement membrane of the regenerated laminar epidermis
(rLE) in chronic laminitis, expression of type VII and type XVII collagen mRNAs in the rLE
was studied applying sequences of two type of murine collagens. On northern blot analysis,
complement DNA (cDNA) probes adjusted from the murine type VII and type XVII collagen
could hybridize with the equine mRNAs, and each signal was detected as single-bands at
approximately 9.5 kb and 5.6 kb, respectively. Contrasting with the expression level of
equine glyceraldehyde-3-phosphate dehydrogenease mRNA, the band of type VII collagen mRNA
in laminitis was stronger than normal, but the type XVII collagen mRNA in laminitis was
less than normal. By in situ hybridization, positive signals in response to the murine
type VII and type XVII collagen mRNA probes could be detected in the equine laminitic rLE
region. From these results, it is concluded that the keratinocytes constructing the rLE in
chronic stage of laminitis can express type VII and type XVII collagen mRNAs and these
expression patterns were different from the normal. 相似文献
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A review of seed production and stock enhancement for commercially important portunid crabs in Japan
Katsuyuki Hamasaki Yasuhiro Obata Shigeki Dan Shuichi Kitada 《Aquaculture International》2011,19(2):217-235
We reviewed the present status of seed production for stock enhancement and evaluated the impact of stocking on commercial
catches in Japan, of portunid crabs particularly Portunus trituberculatus and Scylla paramamosain. The mean survival rate from hatching to first-stage crabs was around 10%, and 20–30% of the larval culture trials conducted
in recent years could not harvest juveniles during seed production. To achieve reliable mass seed production technologies,
measures for controlling disease and the nutritional condition of larvae in seed production tanks are required to be developed.
The main spawning season extends from April/May to July. Reflecting their life cycle characteristics such as high growth rates,
crabs recruit to the fishery after September and largely contribute to the commercial landings until December in the hatching
year. The main release season of juveniles is from June to July. Consequently, released juveniles are expected to contribute
to commercial landings in the release year. Analyses of catch and release statistics in two small bays estimated the yield
from released individuals (YPR, yield per release) at 2.4 g for P. trituberculatus and 3.3–7.7 g for S. paramamosain, which were similar to values reported from tagging surveys. On a major regional basis, catch and release histories of P. trituberculatus highlighted the impact of hatchery releases on commercial landings as 33.6 g YPR in the Seto Inland Sea, where catches and
releases have been greatest. Although the YPR estimates were different between small bays and major regional seas, Japanese
stock enhancement programmes should have had an impact on portunid crab production, dependent on the magnitude of the releases. 相似文献
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At 114 ranches in the Hidaka District of Hokkaido, a total of 1,118 Thoroughbred foals
that were born from January to June 2003 were examined at different times from May to
September of the same year to ascertain the occurrence of clubfoot. Clubfoot was seen in a
total of 179 foals (16%) at 89 ranches (78%). Also, 124 of the 179 foals (69.3%) had
clubfoot of grade II or higher, and it was found that grade I was likely to be overlooked
or rapidly advance. In the present study, the occurrence of clubfoot was higher than
expected in the investigated region. Hence, it is necessary to establish accurate
diagnostic techniques and clubfoot guidelines to minimize the impact. 相似文献
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Hitoshi Obata Noriyuki Inoue Motoaki Matsuoka Masanao Umebayashi 《Soil Science and Plant Nutrition》2013,59(2):439-442
As a result of Cd treatment, K concentrations decreased in Cd sensItive maize and kidney bean calli (Obata et al. 1994) and in intact roots of kidney bean plants (Obata et al. unpublished). Potassium may be extruded from the roots or the absorption of K may be depressed by the Cd treatment in these Cd sensitive plants. Obata et al. (1996) observed that Cd inhibited both the efflux of H+ and influx of K+ following K+ addition in intact roots of bean. Thus Cd may affect the activity of proteins essential to ion movement., i.e. ioncarriers, channels and ATPase embedded in the membranes and/or may affect the permeability of the lipids of the membrane. 相似文献