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Late watergrass (Echinochloa phyllopogon): mechanisms involved in the resistance to fenoxaprop-p-ethyl 总被引：1，自引：0，他引：1
Bakkali Y Ruiz-Santaella JP Osuna MD Wagner J Fischer AJ De Prado R 《Journal of agricultural and food chemistry》2007,55(10):4052-4058
Fenoxaprop-p-ethyl (FE), 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy] propanoate, ethyl ester (R), is an aryloxyphenoxypropionate herbicide for postemergence control of annual and perennial grasses in paddy fields; its site of action is acetyl-coenzyme A carboxylase (ACCase), an enzyme in fatty acids biosynthesis. The possible mechanism(s) of resistance to FE in a resistant biotype of Echinochloa phyllopogon was examined, namely, absorption, translocation, and metabolism of FE and ACCase susceptibility to fenoxaprop acid (FA). Studies of the in vitro inhibition of ACCase discounted any differential active site sensitivity as the basis of resistance to FE. There were differences in absorption rates between biotypes from 3 to 48 h after application (HAA). Biotypes did not differ in either the amounts or the rates of FE translocated; 98% of applied [14C]FE remaining in the treated leaf. However, there was a good correlation between the rate of herbicide metabolism and the plant resistance. The R biotype produced 5-fold less FA and approximately 2-fold more nontoxic (polar) metabolites 48 HAA than the S biotype. Moreover, the higher rate of GSH conjugation in the resistant biotype as compared to the susceptible one indicates that GSH and cysteine conjugation is the major mechanism of resistance of the R biotype against FE toxicity. 相似文献
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Bakkali Kassimi L Madec F Guy M Boutrouille A Rose N Cruciere C 《The Veterinary record》2006,159(16):511-514
Samples of serum from 76 gilts, 1440 sows, 1473 piglets and 3093 finishing pigs from 96 farrow-to-finish herds were tested for antibodies to encephalomyocarditis virus (EMCV) in microtitre serum neutralisation tests employing two strains of virus, one associated with myocarditis and the other with reproductive failure. The total seroprevalence of EMCV infection was 2.48 per cent. There was no significant difference between the seroprevalence of the reproductive failure strain (1.6 per cent) and the myocardial strain (1.85 per cent). The seroprevalence was higher in the gilts (6.57 per cent) and sows (5.13 per cent) than in the piglets (1 per cent) and finishing pigs (1.84 per cent), and the highest titres were observed in the sows (1:540) and finishing pigs (1:640). In the gilts, the difference in seroprevalence between the reproductive failure strain (3.95 per cent) and the myocardial strain (5.33 per cent) was wider than in the other groups. 相似文献
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E Korta A Bakkali L A Berrueta B Gallo F Vicente V Kilchenmann S Bogdanov 《Journal of agricultural and food chemistry》2001,49(12):5835-5842
A study on the possible degradation of amitraz, bromopropylate, coumaphos, chlordimeform, cymiazole, flumethrin, and tau-fluvalinate during the storage of honey was carried out by HPLC. Except amitraz, the other acaricides are stable in this medium for at least 9 months. Degradation studies of amitraz in honey and beeswax were carried out; the degradation products detected in both matrices were 2,4-dimethylphenylformamide (DMF) and N-(2,4-dimethylphenyl)-N'-methylformamidine (DPMF). The reaction rate constants and the half-lives of the amitraz degradation in honey and wax were calculated. Amitraz was nearly completely degraded within 1 day in beeswax and within 10 days in honey. When amitraz-spiked combs are recycled into new beeswax, DMF was found to be the principal degradation product left in pure wax. 相似文献
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M.A. Tnibar DMV PhD J.A. Auer Dr. Med. Vet. MS S. Bakkali DVM 《Journal of Equine Veterinary Science》2001,21(4)
This study was intended to document normal ultrasonographic appearance of the equine elbow and anatomic landmarks useful in clinical imaging. Both forelimbs of five equine cadavers and both forelimbs of six live adult horses were used (4 Arabian-Barbes, 3 Arabs, 2 Anglo-Arabs, 1 Selle Français, 1 Anglo-Hispano-Arab, three to 18 years old). To facilitate the reading of the scans, a zoning system was developed for some anatomic structures. Ultrasonography was performed with a real-time B-mode semi-portable sector scanner using 7.5 & 5 MHz transducers. On one cadaver limb, MRI was performed on a system at 1.5 Tesla, T1 weighted spin echo, TR of 475 msec, RE of 15 msec, image matrix size 179 × 256 pixels. Ultrasonography images were compared with gross anatomy and with MRI scans to provide the normal ultrasonographic representation of the equine elbow. The lateral collateral ligament, the triceps brachii tendon with its subtendinous bursa, the proximal tendon of the ulnaris lateralis and the articular cartilage of the humeral trochlea were easy to examine ultrasonographically. The medial collateral ligament and the distal biceps brachii tendon required more expertise to assess. Ultrasonographic appearance and course of these structures are described. The 7.5 MHz transducer was best to be used. Ultrasonographic findings correlated well with MRI scans and with gross anatomy in the cadavers' limbs. 相似文献
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Mohamed A. Tnibar DMV PhD Joerg A. Auer Dr.Med.Vet. MS Saoussane Bakkali DMV 《Veterinary radiology & ultrasound》1999,40(1):44-57
This study was intended to document normal ultrasonographic appearance of the equine shoulder and anatomic landmarks useful in clinical imaging. Both forelimbs of five equine cadavers and both forelimbs of six live adult horses were used. To facilitate understanding of the images, a zoning system assigned to the biceps brachii and to the infraspinatus tendon was developed. Ultrasonography was performed with a real-time B-mode semiportable sector scanner using 7.5- and 5-MHz transducers. On one cadaver limb, magnetic resonance imaging (MRI) was performed using a system at 1.5 Tesla, T1-weighted spin-echo sequence. Ultrasonography images were compared to frozen specimens and MRI images to correlate the ultrasonographic findings to the gross anatomy of the shoulder. Ultrasonography allowed easy evaluation of the biceps brachii and the infraspinatus tendon and their bursae, the supraspinatus muscle and tendons, the superficial muscles of the shoulder, and the underlying humerus and scapula. Only the lateral and, partially, the caudal aspects of the humeral head could be visualized with ultrasound. Ultrasonographic appearance, orientation, and anatomic relationships of these structures are described. Ultrasonographic findings correlated well with MRI images and with gross anatomy in the cadavers' limbs. 相似文献
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