Periorchitis after tetramisole treatment in bulls implanted with Setaria labiatopapillos     

T A Powe  R D Powers 《Journal of the American Veterinary Medical Association》1985,186(6):588-589

Thirteen mixed-breed beef bulls, 1 to 4 years old, were used to determine the effect of live and dead filarial nematodes, Setaria labiatopapillosa, placed in the vaginal cavity of the testes. When dead worms were used, granulomatous lesions developed on the tunica vaginalis parietalis in 7 of 8 testes. The lesions were similar to those seen in some clinical cases of periorchitis. Similar lesions developed in 5 of 6 testes after live worms were implanted in the vaginal cavity of the testes and tetramisole (8 mg/kg) was injected subcutaneously 6 days after implantation. When live worms were implanted and tetramisole was not given, lesions developed in 3 of 6 testes. It was concluded that the granulomatous reaction was a local response to dead or killed S labiatopapillosa.  相似文献   

Effects of Natural EstradioI-17β and Synthetic 17α- Ethynylestradiol on Direct Feminization of European Sea Bass Dicentrarchus labrax     

Sergei  Gorshkov Galina  Gorshkova Barbara  Colorni Hillel  Gordin 《Journal of the World Aquaculture Society》2004,35(2):167-177

To produce a monosex female population of European sea bass Dicentrarchus labrax, fry were fed dry diets containing dosages of 12.5, 25, and 50 mg/kg food of either the natural estrogen estradiol-170β(E₂) or the synthetic estrogen 17α-ethynylestradiol (EE₂) for 60 d starting at 88 d post-hatch (dph). A complete feminization (100%) was achieved in all E₂-treated groups at the age of 11 mo (330 dph). All affected fish had ovaries similar in size and histological structure to those of control females. In the E₂-treated groups, feminized fish were heavier and longer than untreated controls (males and females combined). In control groups females exhibited significantly higher body weight and total length than males. Untreated females from control groups and females from the group treated with E₂ at 12.5 mg/kg food had similar body weight, suggesting that in sea bass growth is related to phenotypic sex. In the Entreated groups, survival rates were similar to those of the control fish. A relatively high percentage of females was obtained in the EE₂-treated groups (from 38.6 to 96.5%). However, the gonadal development in these fish was significantly suppressed and a dose-dependent reduction of gonadal sizes was evident. Treatments with the EE₂ (12-5, 25, and 50 mg/kg food) resulted in many fish having abnormal (2.9-5.4-39.8%, respectively) and sterile (0.6-6.0-21.6%, respectively) gonads. Effects also included significantly lower weight and shorter length when compared with controls. Furthermore, fish fed with EE₂ at the dosage of 50 mg/kg food had high mortality rate. A simple protocol was developed for the complete feminization in sea bass in which the fry (80-100 dph) were fed to satiation two times daily with a diet containing 12.5 me of E₂/ks food for a period of 60 d.  相似文献   

Möglichkeiten zur Förderung und zum Einsatz von Nützlingen an Stadtbäumen     

Barbara Jäckel  Hartmut Balder  Kristina Hasselmann 《Gesunde Pflanzen》2002,54(7):218-226

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Carrot red leaf associated RNA in carrots in the United Kingdom     

A. Morton  N. J. Spence †  N. Boonham  D. J. Barbara 《Plant pathology》2003,52(6):795-795

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Preliminary study of plasma vascular endothelial growth factor (VEGF) during low- and high-dose radiation therapy of dogs with spontaneous tumors     

Melanie C. Wergin  Med. Vet.    Kurt Ballmer-Hofer  PhD    Malgorzata Roos  PhD    Roger E. Achermann  Med. Vet.    Natalie Inteeworn  Med. Vet.    Margarete K. Akens  Med. Vet.    Hans Blattmann  PhD    Barbara Kaser-Hotz  Dr. Med. Vet. 《Veterinary radiology & ultrasound》2004,45(3):247-254

High plasma vascular endothelial growth factor (VEGF) concentrations are associated with radiation resistance and poor prognosis. After an exposure to ionizing radiation in cell culture an early phase and a late phase of increased VEGF have been documented. The activation was dependent on the radiation dose. Therefore, the purpose of this study was to measure baseline plasma VEGF and changes in VEGF over the course of fractionated radiation therapy in dogs with spontaneous tumors. Dogs with tumors had a significantly higher pretreatment plasma VEGF than did dogs without tumors. Immediately after irradiation no increased plasma VEGF was observed. Over the course of radiation therapy there was an increased plasma VEGF in dogs treated with low doses per fraction/high total dose, whereas plasma VEGF remained stable in dogs irradiated with high doses per fraction/low total dose. The regulatory mechanisms are very complex, and therefore the value of plasma VEGF measurements as an indirect marker of angiogenesis induced by radiotherapy is limited.  相似文献   

Characterization of a wild-type strain of Francisella tularensis isolated from a cat.     

Thomas J Inzana  Gretchen E Glindemann  Gerald Snider  Susan Gardner  Lisa Crofton  Barbara Byrne  Joseph Harper 《Journal of veterinary diagnostic investigation》2004,16(5):374-381

Francisella tularensis type A is the primary cause of tularemia in animals and humans in North America. The majority of research on F. tularensis has been done with the attenuated live vaccine strain (LVS), which is a type B, but very few wild-type F. tularensis strains have been characterized. A gram-negative coccobacillus that was isolated in pure culture from the lungs of a cat that died after being lost for 5 days was received for identification at the Virginia-Maryland Regional College of Veterinary Medicine Teaching hospital. The isolate (strain TI0902) was not identified (or was misidentified) by commercial identification systems; however, it was identified as F. tularensis subspecies tularensis (type A) by sequencing a portion of the 16S ribosomal RNA gene. Furthermore, repetitive extragenic palindromic sequences-polymerase chain reaction amplified a 4-kb DNA fragment from TI0902 that was characteristic of F. tularensis type A but not type B. The electrophoretic profile of the lipopolysaccharide of strain TI0902 was identical to that of the LVS by Western blotting with antiserum to LVS. The protein-enriched outer membrane of strain TI0902 contained 6-8 proteins, which were similar in molecular size to those from the LVS. Electron microscopy of negatively stained and alcian blue-stained LVS and TI0902 cells showed that both strains were coccobacillary in shape and may be encapsulated. However, after mouse challenge, the TI0902 strain was clearly more virulent than the LVS strain. Results of this study indicate that the genotype and phenotype of wild-type F. tularensis type A strain TI0902 is similar, but not identical, to that of the LVS strain. Further studies will help determine whether pathogenesis and host-pathogen interactions are also similar between the 2 strains.  相似文献   

Treatment of canine haemangiosarcoma with suberoylanilide hydroxamic acid, a histone deacetylase inhibitor     

L. A. Cohen  B. Powers  S. Amin  D. Desai 《Veterinary and comparative oncology》2004,2(4):243-248

A case report is presented by describing the treatment of a 12‐year‐old dog – diagnosed with haemangiosarcoma (HSA) – with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) inhibitor. The drug was administered orally, on a daily basis, approximately 2 weeks post‐splenectomy at a dose of 3 mg kg^?1. HSA is a lethal malignancy of the endothelium, which is usually disseminated by the time it is diagnosed. Median survival time, usually, is no longer than 80 days. Following treatment with SAHA, no sign of malignant growth could be discerned by means of diagnostic abdominal ultrasound, chest X‐ray or with the help of clinical symptoms, over a period of >1000 days. The precise mechanism by which HDAC inhibitors exert their anti‐cancer effects is uncertain, but evidence suggests that exposure to SAHA generates hyperacetylated chromosomal histones, which, in turn, facilitates the expression of tumour suppressor genes turned off by epigenetic mechanisms during neoplastic transformation of the endothelium.  相似文献   

A perspective on the measurement of time in plant disease epidemiology   总被引：2，自引：1，他引：2  

D. J. Lovell †  S. J. Powers  S. J. Welham  S. R. Parker 《Plant pathology》2004,53(6):705-712

The growth and development of plant pathogens and their hosts generally respond strongly to the temperature of their environment. However, most studies of plant pathology record pathogen/host measurements against physical time (e.g. hours or days) rather than thermal time (e.g. degree-days or degree-hours). This confounds the comparison of epidemiological measurements across experiments and limits the value of the scientific literature.  相似文献   

Prognostic value of echocardiographic indices of left atrial morphology and function in dogs with myxomatous mitral valve disease          下载免费PDF全文

Marco Baron Toaldo  Giovanni Romito  Carlo Guglielmini  Alessia Diana  Nazzareno G. Pelle  Barbara Contiero  Mario Cipone 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(3):914-921

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Validation of the Accutrend Plus point‐of‐care triglyceride analyzer in horses,ponies, and donkeys          下载免费PDF全文

Michaela C. Pongratz Dr. med vet  DECEIM  FVH  Hannah K. Junge Dr. med vet  Barbara Riond Dr. med vet  FVH  Colin C. Schwarzwald Dr. med vet  PhD  DACVIM  DECEIM 《Journal of Veterinary Emergency and Critical Care》2016,26(5):682-690

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