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Three groups of horses and ponies (N = 13, 13 and 12) were treated with ivermectin paste (0.2 mg/kg p.o.), avermectin B1 solution (0.2 mg/kg p.o.), or fenbendazole suspension (10 mg/kg via nasogastric tube). The avermectin B1 was a 1% solution in a propylene glycolglycerol formal base. Faecal strongyle egg counts were performed before, and 14, 28, 42, 56 and 70 d, after treatment. Full-thickness skin biopsies from the neck, pectoral and umbilical regions were examined for Onchocera microfilaria before treatment, and again 14 and 70 d later. Ivermectin therapy produced a significant (P less than 0.01) decrease in mean strongyle egg counts 14, 28, 42 and 56 d after treatment. Avermectin B1 therapy resulted in significant (P less than 0.01) decreases in mean strongyle egg counts 14, 28 and 42 d after treatment. All horses given ivermectin or avermectin B1 had zero strongyle egg counts 14 and 28 d after treatment. Fenbendazole failed to significantly decrease strongyle egg counts. Both ivermectin and avermectin B1 resulted in zero microfilaria counts in all horses 14 d after treatment. On day 70 the percentage decrease in microfilaria counts were 100% and 99.6% respectively. Fenbendazole failed to significantly decrease microfilaria counts. The oral administration of this formulation of avermectin B1 appeared to be highly efficacious against intestinal strongyles and Onchocera microfilaria. The duration of anti-strongyle activity was, however, significantly (P less than 0.01) shorter than that of ivermectin paste. 相似文献
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Bertolini S Maurella C Bona C Ingravalle F Desiato R Baioni E Chiavacci L Caramelli M Ru G 《Veterinary research》2012,43(1):63
ABSTRACT: A sudden increase in the incidence of scrapie in Italy in 1997 was subsequently linked to theuse of a potentially infected vaccine against contagious agalactia. The relative risk for theexposed farms ranged between 6 and 40. The aim of this study was to assess the long-termimpact of exposure to the potentially scrapie-contaminated vaccine on the Italian classicalscrapie epidemic. We carried out a retrospective cohort study, fitting mixed-effects Poissonregression models, dividing national geographic areas into exposure categories on the basis ofthe vaccine circulation levels. We took into account the sensitivity of the surveillance systemapplied in the different areas. The population attributable fraction (PAF) was used to assessthe impact on the total population of farms associated with the effect of circulation of thevaccine. The provinces where the vaccine was more often sold were noted to have a higherlevel of disease when compared to those provinces where the vaccine was sold less often(incidence rate ratio [IRR]: 2.7; 95% confidence interval [CI]: 1.1-6.5). The populationattributable fraction was high (68.4%). Standardization techniques allowed to account for thepotential of geographical variability in the sensitivity of the Italian surveillance system.Although the number of the directly exposed farms was limited, an important long-termimpact of the vaccine circulation could be quantified in terms of secondary outbreaks likelydue to the exchange of animals from directly exposed flocks. 相似文献
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Surgical resection of a dysgerminoma in a mare 总被引:1,自引:1,他引:0
A mare was referred for further evaluation of a mass found in the left caudal abdomen during a routine postpartum reproductive palpation. The mare was clinically normal with no history of health problems. Ultrasonographic examination of the mass confirmed its presence, but the origin of the mass could not be accurately determined. Routine haematology and serum biochemistry results were within normal limits. The mare was initially treated conservatively with antibiotics, but the mass continued to increase in size, so it was surgically excised. The mass involved the left ovary. The mare showed transient abdominal pain after surgery, but developed no other complications and was in foal 7 months later. On histology, the mass was diagnosed as a dysgerminoma, a rare ovarian tumour of germ cell origin. 相似文献
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De Bona Gicele Sbardelotto Vincenzi Simone De Marchi Fabiola Angelini Elisa Bertazzon Nadia 《植物病害和植物保护杂志》2021,128(3):715-724
Journal of Plant Diseases and Protection - In the present study, a commercial chitosan soluble in acid solution and obtained from shrimp shell waste, with a molecular weight of 173 kDa and... 相似文献
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牛传染性疱疹病毒4(BoHV-4)是一种微疱疹病毒,普遍存在于牛群中,可以从感染牛的血清和牛奶中分离出来.研究结果表明,某些人体细胞对BoHV-4也有易感性,目前试验观察到人体细胞不会对BoHV-4持续感染,同时可以防止肿瘤坏死α-因子导致的细胞凋零.总之,所有现象表明,BoHV-4有害于公共健康.为了对人体通过牛奶和血清感染BoHV-4的率进行评估,对BoHV-4适当加热处理.对牛奶巴氏消毒以及血清加热脱补体作用进行灭活,可消除BoHV-4的传染性.因此,试验结果表明,经过适当处理可显著降低牛奶和血清中BoHV-4对人体感染的机率. 相似文献
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TD ST GEORGE 《Australian veterinary journal》1989,66(12):393-395
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Candido MV Silva LC Moura J Bona TD Montiani-Ferreira F Santin E 《Journal of zoo and wildlife medicine》2011,42(3):437-443
The Cracidae family of neotropical birds is regarded as one of the most severely threatened in the world. They traditionally have been extensively hunted, and, thus, ex situ efforts for their conservation are recommended and involve the optimization of their care in captivity. Nutrition is a fundamental aspect of husbandry, which influences survival and reproduction in captivity. In this study, a total of 29 animals, including 3 species (Penelope obscura, Penelope superciliaris, and Aburria jacutinga), were subjected to monthly physical examination and blood sampling before and after dietary conversion from the traditional diet of broiler feed, fruits, and vegetables to a nutritionally balanced commercial diet specifically designed for wild Galliformes. The diet change produced differences in several parameters tested, including an increase (P < 0.05) in hemoglobin concentration for all species. Increases (P < 0.05) in erythrocyte count, packed cell volume, and body weight were observed in P. obscura, with a concomitant decrease in the standard deviation for such parameters that show improved uniformity. Globulins and lipase also were reduced (P < 0.05) in P. obscura. Although leukocyte count was lowered and eosinophils were increased in all 3 species after dietary conversion, only these 2 changes were significant (P < 0.05) in P. superciliaris. A. jacutinga had higher (P < 0.05) blood glucose concentrations than the other species, but diet had no effect on this parameter. Blood uric acid concentrations were higher (P < 0.05) after conversion to the commercial diet in P superciliaris. The provision of a commercial extruded diet as a single food source was beneficial, which led to a general improvement in clinical aspects and group uniformity in these 3 species of Cracidae. 相似文献