Pathotyping and antimicrobial susceptibility testing of Escherichia coli isolates from neonatal calves     

Khawaskar  Damini P.  Sinha  D. K.  Lalrinzuala  Michael V.  Athira  V.  Kumar  Manish  Chhakchhuak  Lalsangzuala  Mohanapriya  K.  Sophia  I.  Abhishek  Kumar  O. R. Vinodh  Chaudhuri  Pallab  Singh  B. R.  Thomas  Prasad 《Veterinary research communications》2022,46(2):353-362

Neonatal calf mortality is a major concern to livestock sector worldwide. Neonatal calf diarrhoea (NCD), an acute severe condition causes morbidity and mortality in calves. Amongst various pathogens involved in NCD, E. coli is considered as one of the major causes. The study was targeted to characterize E. coli isolates from neonatal calves for diarrhoeagenic Escherichia coli (DEC) types (pathotyping), antimicrobial resistance (AMR) profiling and to correlate with epidemiological parameters. From neonates, a total of 113 faecal samples were collected, out of that 308, lactose fermenting colonies were confirmed as E. coli. Pathotypable isolates (12.3%) were represented by STEC (6.1%), EPEC (2.9%), ETEC (1.9%), EAEC (0.9%) and EHEC (0.3%). Occurrence of STEC was more in non-diarrhoeic calves, whereas ETEC was observed more in diarrhoeic calves. EPEC occurrence was observed in both diarrhoeic and non-diarrhoeic calves. Fishers extract test showed no significant association for occurrence of DEC types to type of dairies, health status, species, breed, age and sex of neonatal calves. Two hundred and eighty isolates were tested for antimicrobial susceptibility. The isolates showed maximum resistance towards ampicillin (55.4%) followed by tetracycline (54.3%), while minimum resistance was observed towards meropenem (2.5%). Multidrug resistant E. coli isolates were found to be 139 (49.6%), and Extended-spectrum beta-lactamase (ESBL) producers were 120 (42.9%). DEC pathotypes like STEC, ETEC, EHEC and EAEC that are also multidrug resistant present in neonatal calves have zoonotic potential and hence are of public health significance.

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Effects of altitude on circadian rhythm of adult locomotor activity in Himalayan strains of Drosophila helvetica     

Keny Vanlalhriatpuia  Vanlalnghaka Chhakchhuak  Satralkar K Moses  SB Iyyer  MS Kasture  AJ Shivagaje  Barnabas J Rajneesh  Dilip S Joshi 《Journal of circadian rhythms》2007,5(1):1-11

Background  

We recently reported that the altitude of origin altered the photic and thermal sensitivity of the circadian pacemaker controlling eclosion and oviposition rhythms of high altitude Himalayan strains of Drosophila ananassae. The present study was aimed at investigating the effects of altitude of origin on the pacemaker controlling the adult locomotor activity rhythm of D. helvetica.  相似文献