Tests of anthelmintic activity (utilizing experimental challenge) against the migratory stages of Strongyloides ransomi in pigs     

S E Leland  G E Combs 《American journal of veterinary research》1965,26(113):932-938

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Development of an assay to determine the bioavailability of potassium in feedstuffs for the young pig     

N R Combs  E R Miller  P K Ku 《Journal of animal science》1985,60(3):709-714

A series of four trials was conducted to verify the published requirement of .26% total K in the diet and to identify response variables useful in an assay of the bioavailability of K in feedstuffs for the young pig. Purified diets were supplemented with K at four levels as KC2H3O2 in three trials and as KHCO3 in the fourth trial. In the first three trials, the requirement was estimated by least-squares analysis of a linear-plateau response of average daily gain. Additional measures in each trial were taken for linear response to dietary K levels. The three estimates of K requirement obtained were .30, .33 and .26% total K in the diet. These three estimates were not found to be inconsistent with the published value of .26% total K in the diet. Various urinary and hematological measures also were examined during the four trials for linear response to dietary K levels. Plasma K was the only hematological response to show a significant linear relationship to dietary K levels. Urinary K concentrations and daily excretion showed a highly significant linear response to dietary K levels. Based on these results, a K bioavailability assay using urinary K measures as the primary response variable and plasma K as the secondary response variable seems the most promising.  相似文献   

Luteoma in two mares treated by ovariectomy     

E. Combs  T. Beachler  J. R. Troy  A. Olds-Sanchez  J. M. Howard  A. Fales-Williams  M. Yaeger  D. M. Tatarniuk 《Equine Veterinary Education》2022,34(8):e318-e322

A 15-year-old Paint mare (Case 1) and a 15-year-old Arabian mare (Case 2) were presented for aggressive and undesired behaviour. Reproductive evaluation revealed, initially, an enlarged ovary with a smaller/normal sized contralateral ovary in each case. Granulosa cell tumour (GCT) panel testing revealed elevated inhibin B in both cases and elevated anti-Mullerian hormone (AMH) levels only in Case 1 determined from currently established reference ranges. Based on a presumptive diagnosis of GCT, bilateral standing ovariectomy was elected for both mares. In each case neoplastic tissue consistent with luteoma was detected only on histological examination in the smaller/normal sized left ovary; the right ovary appearing normal. Long-term follow-up was performed 1 year and 5 years post-operatively by telephone. The owners were satisfied with the outcome and each patient demonstrated resolution of aggressive stallion-like behaviour. Each case returned to the owners' intended use. In conclusion, luteoma should be considered as a differential diagnosis for ovarian neoplasms in horses related to behavioural abnormalities, even in normal-sized ovaries.  相似文献   

Efficacy of vaginal spaying and anabolic implants on growth and carcass characteristics in beef heifers   总被引：2，自引：0，他引：2  

M J Garber  R A Roeder  J J Combs  L Eldridge  J C Miller  D D Hinman  J J Ney 《Journal of animal science》1990,68(5):1469-1475

Ninety crossbred beef heifers averaging 260 kg were blocked by weight and allotted randomly to 15 pens of six heifers each, with three replicates per treatment. The treatments were spayed heifers (S); intact heifers (I); S + Synovex-H7 (SH); I + Synovex-H (IH); and S + Synovex-S7 (SS). The heifers were spayed vaginally with a Willis instrument; intact heifers were rectally palpated for reproductive soundness. Heifers were fed a growing diet (55 d), re-implanted and subsequently fed a finishing ration (73 or 101 d). All heifers were observed for estrus daily at approximately 0600 and 2000 until d 69. A jugular vein blood sample was obtained from each heifer on d 48, 55, 62 and 69 for blood progesterone analysis. Results of blood progesterone analysis and reproductive tract examination indicated that two spayed heifers were incompletely spayed, a 96% success rate. The SH and SS heifers continued to exhibit estrous behavior despite being successfully spayed. Heifers implanted with Synovex-H had greater (P less than .01) ADG and were more efficient (P less than .03) than nonimplanted heifers. The SS heifers had greater ADG (P less than .05) during the finishing phase than SH heifers, but no advantage of SS over SH was apparent during the growing phase. The overall ADG response to implantation was fourfold greater (P less than .07) in the spayed heifers than in the intact heifers (32 vs 8%). Heifers implanted with Synovex-H had greater adjusted hot carcass weight (P less than .02) and ribeye area (P less than .002) than nonimplanted heifers. For adjusted live weight and ribeye area, the response to implantation was approximately threefold greater in the spayed heifer than the intact heifer. These results demonstrate that spaying and implanting heifers can increase rates and efficiency of gain even though behavioral estrus is not eliminated.  相似文献   

Fat supplementation of diets containing a high level of oats for growing-finishing swine.     

R O Myer  G E Combs 《Journal of animal science》1991,69(12):4665-4669

Two 2 x 2 factorial arrangement trials were conducted to evaluate the effectiveness of fat supplementation in improving the energy value of diets containing a high level of a fibrous feedstuff (oats) for growing-finishing swine. Corn-soybean meal-based diets were used that contained either 0 or 40% ground oats and either 0 or 3% added fat. Each trial used 120 pigs (27 kg) with each treatment assigned to five pens of six pigs each. Growing diets (.80% lysine for basal diet) were given from 27 to 55 kg live weight and finishing diets (.64% lysine) from 55 to 102 kg. Diets were formulated to a constant calculated ME to lysine ratio within the growing and finishing phases. Apparent digestibilities of DM and energy were determined for the growing and finishing diets by the indigestible marker (chromic oxide) method. The inclusion of oats in the diets resulted in poorer (P less than .01) feed conversion efficiency and reduced (P less than .01) apparent DM and energy digestibilities. The addition of fat improved (P less than .01) feed conversion efficiency but had no effect (P greater than .10) on DM or energy digestibility. The improvements noted for feed conversion efficiency were similar (P greater than .10) regardless of the dietary oat content. The 3% dietary fat supplementation was equally effective in improving feed conversion efficiency whether the diets did contain or did not contain ground oats for growing-finishing swine.  相似文献   

A mathematical model of the United States beef production system     

W.C. Miller  G.M. Ward  T.P. Yorks  D.L. Rossiter  J.J. Combs 《Agricultural Systems》1980,5(4):295-307

Dynamic linear programming was used to model the US beef production system, to determine the cattle cycle effects on feeder cattle supplies and to select feeding options that would maximise USDA choice and prime quality grade beef production. The model represented the US as a five-region beef production system with inter-regional transportation of offspring for feeding purposes. Cow weights, offspring weaning weights and feed efficiency were different for each region, but the feeding activities were the same in each region except for region two. In region two the feeding of grain to steer and heifer offspring was not an industry practice. Dynamic properties of the model were achieved through constraints that transferred animals from year zero (initial condition) to year five using calving, cow culling, replacement heifer and death loss rates as controlling parameters. The results of model exercises that used historical parameter values indicate that there will be a significant decrease in the supply of beef at all grade levels over the next five years. They also suggest that it is more economically efficient to feed calves from the southeastern and northern parts of the USA if they are transported to the southwestern region.  相似文献   

Effect of raw and heated soybeans on gain, nutrient digestibility, plasma amino acids and other blood constituents of growing swine     

G E Combs  R G Conness  T H Berry  H D Wallace 《Journal of animal science》1967,26(5):1067-1071

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Typing of Australian isolates of Treponema hyodysenteriae by serology and by DNA restriction endonuclease analysis.     

B G Combs  D J Hampson  S J Harders 《Veterinary microbiology》1992,31(2-3):273-285

A total of 91 isolates of Treponema hyodysenteriae which were obtained from 62 piggeries located around Australia were typed by serology and by DNA restriction endonuclease analysis (REA). The isolates fell into eight serogroups, of which groups B and D were the most common. Isolates with different REA patterns were recognised within serogroups, whilst a few isolates with the same REA pattern were placed into different serogroups. Some of the latter isolates were either from the same piggery or from farms with epidemiological links, thus indicating the bacteria may have altered their antigenic properties. A total of 31 different REA patterns were recognised amongst the Australian isolates. These comprised eight major patterns, with four of these being subdivided on the basis of minor differences in banding. Where a number of isolates were obtained from individual piggeries these all had the same REA pattern, and in one piggery isolates with the same pattern were recovered over a five year period. Plasmid bands were observed in 70 of the Australian isolates (77%), and in six of the seven overseas isolates included in the study for comparison. These plasmids did not affect the REA pattern. Of the States from which substantial numbers of isolates were examined, the greatest number of different strains (12 amongst 19 piggeries) were found from Victoria, and there were 10 REA patterns in strains from 24 piggeries in Queensland. Despite the large total number of different strains of T. hyodysenteriae in Australia, only three were found in more than one State.  相似文献   

Effects of additional feed during late gestation on reproductive performance of sows: a cooperative study   总被引：4，自引：0，他引：4  

G L Cromwell  D D Hall  A J Clawson  G E Combs  D A Knabe  C V Maxwell  P R Noland  D E Orr  T J Prince 《Journal of animal science》1989,67(1):3-14

A cooperative research study involving 1,080 litters was conducted at eight stations to determine the effects of additional feed during the last 23 d of gestation on reproductive performance of sows and on preweaning performance of their pigs. Primiparous and multiparous sows were fed fortified corn- or sorghum-soybean meal diets (14% crude protein). Control sows received 1.82 kg/d from March through November and 2.27 kg/d from December through February. Treated sows were fed an additional 1.36 kg of feed/d from d 90 of gestation to farrowing. Sows were allowed to consume the same diet ad libitum during a 21-d lactation. Additional feed in late gestation resulted in greater (P less than .001) sow weight gain from d 90 to d 110 of gestation (16.8 vs 9.0 kg) and greater (P less than .001) parturition-lactation weight loss (21.3 vs 16.4 kg). Total weight gain from breeding to 21 d of lactation favored sows that received extra feed (27.5 vs 22.7 kg; P less than .001). Sows receiving extra feed had more live pigs at farrowing (10.05 vs 9.71, P = .06) and at 21 d postpartum (8.35 vs 8.06, P = .09), and the pigs were heavier at birth (1.48 vs 1.44 kg, P = .003) and at 21 d (5.37 vs 5.20 kg, P = .006). Lactation feed intake and number of days from weaning to estrus were not affected by treatment. The results indicate that additional feed in late gestation improves reproductive performance in sows. In this study, the cost of an additional 31 kg of feed/sow was more than offset by the value of the additional sow weight gain (approximately 5 kg), the additional .3 of a pig/litter at weaning and the additional 2.6 kg of total litter weaning weight.  相似文献   

The selenium requirement of the puppy     

Wedekind KJ  Yu S  Combs GF 《Journal of animal physiology and animal nutrition》2004,88(9-10):340-347

Current selenium (Se) recommendations for the puppy are based on extrapolation from other species (0.11 mg Se/kg diet). The purpose of this study was to experimentally determine the Se requirement in puppies. Thirty beagle puppies (average = 8.8 weeks old) were utilized in a randomized complete block design with age, litter and gender used as blocking criteria. Puppies were fed a low Se (0.04 mg Se/kg diet) torula yeast-based diet for 14 days (pre-test period) after which this same diet was supplemented with five levels of Na2SeO3 for 21 days (experimental period) to construct a response curve (0, 0.13, 0.26, 0.39 or 0.52 mg Se/kg diet). Response variables included Se concentrations and Se-dependent glutathione peroxidase activities (GSHpx) in serum as well as serum total triiodothyronine (TT3), serum total thyroxine (TT4) and serum free T4 (FT4). No significant changes in food intake and body weight gain occurred, and no clinical signs of Se deficiency were observed. A breakpoint for serum GSHpx could not be determined in our study due to analytical difficulties. A broken-line, two-slope response in serum Se occurred with a breakpoint at 0.17 mg Se/kg diet. When Se from the basal diet was added to this estimate, the breakpoint for serum Se equated to 0.21 mg Se/kg diet. TT3 increased linearly with increasing Se intake, whereas TT4 was unchanged. However, the ratio of TT4 : TT3 decreased linearly in response to supplemental Se. In summary, although we estimated the selenium requirement for the puppy based on serum Se, our 0.21 mg Se/kg diet estimate is higher than that seen for adult dogs, kittens, rats or poultry (0.13, 0.15, 0.15 and 0.15 mg Se/kg diet respectively). This difference may be due to the fact that GSHpx was used as the biomarker of Se status.  相似文献